Опубликована: Янв. 1, 2024
Язык: Английский
Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Янв. 26, 2025
The supercritical antisolvent (SAS) method can effectively improve the bioavailability of poorly water-soluble drugs. However, current equipment and processes were not fully developed, making industrialization difficult to achieve. Therefore, an externally adjustable annular gap nozzle its supporting designed. Curcumin was used as a model drug, ethanol solvent, carbon dioxide (SC-CO2) antisolvent. Building on single-factor experiments, Box-Behnken Design-Response Surface Methodology (BBD-RSM) employed systematically investigate effects four process parameters—crystallizer pressure (12–16 MPa), crystallizer temperature (313–323 K), solution concentration (1–2 mg/mL), CO2/solution flow rate ratio (133–173 g/g)—on morphology particle size curcumin particles. Using scanning electron microscopy (SEM) dynamic light scattering (DLS) analyses, morphologies mean diameter ranges examined. To look into how SAS affects TML's chemical physical characteristics, X-ray diffraction analysis (XRD) Fourier-transform infrared spectroscopy (FT-IR) further performed. Experimental results show that, had greatest effect size, followed by concentration, while least influence. optimum conditions are operational set with 15 MPa, 320 K, 1.2 mg/mL, 134 g/g, resulting in submicron particles average 808 nm being obtained. This study demonstrated feasibility associated process, showcasing significant potential for reducing enhancing
Язык: Английский
Процитировано
1
Nano Energy, Год журнала: 2024, Номер 129, С. 110082 - 110082
Опубликована: Авг. 3, 2024
Язык: Английский
Процитировано
8
Surface and Coatings Technology, Год журнала: 2025, Номер unknown, С. 131984 - 131984
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
IGI Global eBooks, Год журнала: 2025, Номер unknown, С. 1 - 30
Опубликована: Март 28, 2025
The convergence of the Internet Things (IoT) and Machine Learning (ML) is reshaping industries by enabling smarter, data-driven decision-making operational efficiencies. This chapter delves into foundational principles IoT, illustrating how interconnected devices generate vast amounts real-time data. It then explores role ML algorithms in analyzing this data to uncover patterns, optimize processes, enhance automation. discusses emerging trends such as adoption 5G networks for improved connectivity, federated learning decentralized processing, expanding artificial intelligence predictive analytics Additionally, it highlights importance continuous adaptation these rapidly evolving fields, well potential groundbreaking innovations both everyday applications industrial operations. By addressing opportunities challenges, provides a comprehensive understanding IoT are shaping future technology society.
Язык: Английский
Процитировано
0
Materials Chemistry and Physics, Год журнала: 2025, Номер 341, С. 130919 - 130919
Опубликована: Апрель 22, 2025
Язык: Английский
Процитировано
0
Journal of Manufacturing and Materials Processing, Год журнала: 2025, Номер 9(5), С. 144 - 144
Опубликована: Апрель 28, 2025
This paper designs a Dual path cold spray nozzle and studies its performance during the process through numerical simulations optimization experiments. The gas flow field inside particle acceleration were simulated using Fluent software2020R1. orthogonal experimental method was used to analyze effects of five geometric parameters on performance, determining optimal design parameter combination. Modeling simulation calculations based combination showed that average impact velocity increased by nearly 17 m/s, number particles exceeding theoretical critical 100, deposition efficiency improved 10%. Experimental results indicated compared single-channel nozzle, from 20.22% 28.26%, porosity 10.51% 9.12%, microhardness also increased. test data in good agreement with previous results, validating accuracy model providing an important reference for improvement subsequent parameters.
Язык: Английский
Процитировано
0
Surface and Coatings Technology, Год журнала: 2025, Номер unknown, С. 132274 - 132274
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
International Journal of Refrigeration, Год журнала: 2025, Номер unknown
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
Surface and Coatings Technology, Год журнала: 2024, Номер 483, С. 130711 - 130711
Опубликована: Апрель 2, 2024
Язык: Английский
Процитировано
3
Micromachines, Год журнала: 2024, Номер 15(4), С. 464 - 464
Опубликована: Март 29, 2024
In dye-sensitized solar cells (DSSCs), the counter electrode (CE) plays a crucial role as an electron transfer agent and regenerator of redox couple. Unlike conventional CEs that are generally made glass-based substrates (e.g., FTO/glass), polymer appear to be emerging candidates, owing their intrinsic properties lightweight, high durability, low cost. Despite great promise, current manufacturing methods on polymeric suffer from serious limitations, including conductivity, scalability, process complexity, need for dedicated vacuum equipment. present study, we employ evaluate fully additive route can enable fabrication DSSCs in high-throughput eco-friendly manner with improved performance. The proposed approach sequentially comprises: (1) material extrusion 3-D printing substrate; (2) conductive surface metallization through cold spray particle deposition; (3) over-coating thin-layer catalyzer graphite pencil. fabricated electrodes characterized terms microstructure, electrical photo-conversion efficiency. Owing its promising conductivity (8.5 × 104 S·m−1) micro-rough structure (Ra ≈ 6.32 µm), additively manufactured led ≈2.5-times-higher efficiency than traditional FTO/glass. results study suggest advance field by addressing limitations CE platforms.
Язык: Английский
Процитировано
2