Journal of Biomechanics,
Год журнала:
2024,
Номер
179, С. 112484 - 112484
Опубликована: Дек. 13, 2024
A
search
in
Scopus
within
"Article
title,
Abstract,
Keywords"
unveils
2,444
documents
focused
on
the
biomechanics
of
Abdominal
Aortic
Aneurysm
(AAA),
mostly
AAA
wall
stress.
Only
24
investigated
kinematics,
an
important
topic
that
could
potentially
offer
significant
insights
into
AAA.
In
this
paper,
we
present
image-based
approach
for
patient-specific,
vivo,
and
non-invasive
kinematic
analysis
using
patient's
time-resolved
3D
computed
tomography
angiography
(4D-CTA)
images,
with
objective
to
measure
displacement
strain
during
cardiac
cycle.
Our
relies
regularized
deformable
image
registration
estimating
displacement,
estimation
local
as
ratio
its
normal
radius
curvature,
surface
fitting
non-deterministic
outlier
detection
curvature.
We
verified
our
against
synthetic
ground
truth
data
created
by
warping
a
3D-CTA
realistic
field
obtained
from
finite
element
biomechanical
model.
applied
assess
displacements
strains
ten
patients.
results
indicated
99th
percentile
circumferential
strain,
among
all
patients,
ranged
2.62%
5.54%,
average
4.45%
standard
deviation
0.87%.
also
observed
are
significantly
lower
than
those
healthy
aorta.
work
demonstrates
registration-based
measurement
direction
is
sufficiently
accurate
reliably
estimate
these
displacements.
Biomechanics and Modeling in Mechanobiology,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 26, 2024
An
ascending
aortic
aneurysm
is
an
often
asymptomatic
localized
dilatation
of
the
aorta.
Aortic
rupture
a
life-threatening
event
that
occurs
when
stress
on
wall
exceeds
its
mechanical
strength.
Therefore,
patient-specific
finite
element
models
could
play
important
role
in
estimating
risk
rupture.
This
requires
not
only
geometry
aorta
but
also
nonlinear
anisotropic
properties
tissue.
In
this
study,
we
presented
methodology
to
estimate
from
magnetic
resonance
imaging
(MRI).
As
theoretical
framework,
used
which
added
noise
simulate
clinical
data
real
patient
and
different
healthy
aneurysmal
tissues
collected
literature.
The
proposed
considered
properties,
zero
pressure
geometry,
heart
motion,
external
tissue
support.
addition,
analyzed
as
homogeneous
material
heterogeneous
model
with
for
descending
parts.
was
applied
pre-surgical,in
vivo
MRI
who
underwent
surgery
during
sample
obtained.
results
were
compared
those
obtained
ex
biaxial
test
patient's
sample.
showed
promising
after
successfully
recovering
all
cases.
study
demonstrates
variable
optimization
process
can
affect
result.
particular,
variables
such
principal
strains
found
obtain
more
realistic
materials
than
displacement
field.
Cuadernos de Educación y Desarrollo,
Год журнала:
2024,
Номер
16(13), С. e6742 - e6742
Опубликована: Дек. 2, 2024
Estudos
de
simuladores
do
sistema
cardiovascular
(SCV)
têm
auxiliado
amplamente
nas
áreas
anatômica,
fisiológica
e
sistêmica,
principalmente
pela
validação
testes
in
vitro.
Apesar
explorados
em
modelos
auxiliares
intervenções
emuladores
cardiopatias,
há
atualmente
uma
carência
dispositivos
para
treinamento
interpretação
condições
patológicas.
Esta
revisão
buscou
relacionar
artigos
sobre
o
tema,
baseados
fluido-mecânicos,
com
objetivo
conceituar
desenvolvimento
um
dispositivo
aprendizado
simulado
na
área
da
saúde.
Realizou-se
busca
fontes
pesquisa
principais
bases
dados,
utilizando
palavras-chave
inglês,
inicialmente,
acordo
os
termos
aplicados
títulos
resumos:
"cardiovascular
and
circulatory
model".
Posteriormente,
foram
utilizadas
as
palavras
"lumped/mock/benchwork"
qualquer
campo
e,
por
fim,
"fluido"
completar
escopo
busca.
Foram
realizadas
triagens
quantitativa
qualitativa.
Ao
final,
identificados
17
que
continham
a
ideia
inicial
proposta,
classificados
especificidade
entre
sistemas
circulatório,
híbrido.
Nos
últimos
anos,
surgiu
necessidade
capacitação
humana
interpretar
resultados
clínicos.
Os
estudos
simulações
podem
ser
integrados
utilizados
refinar
aprimorar
ajudando
no
entendimento
das
patologias
auxiliando
nessa
ambientes
pré-intervenções
ou
aprendizado.
O
emprego
ferramentas
computacionais
novas
tecnologias
IoT
é
consenso
maioria
dos
observados.
A
diversidade
mostra
possibilidade
simulador
integrado,
efetivo,
multidisciplinar
economicamente
acessível.
Journal of Biomechanics,
Год журнала:
2024,
Номер
179, С. 112484 - 112484
Опубликована: Дек. 13, 2024
A
search
in
Scopus
within
"Article
title,
Abstract,
Keywords"
unveils
2,444
documents
focused
on
the
biomechanics
of
Abdominal
Aortic
Aneurysm
(AAA),
mostly
AAA
wall
stress.
Only
24
investigated
kinematics,
an
important
topic
that
could
potentially
offer
significant
insights
into
AAA.
In
this
paper,
we
present
image-based
approach
for
patient-specific,
vivo,
and
non-invasive
kinematic
analysis
using
patient's
time-resolved
3D
computed
tomography
angiography
(4D-CTA)
images,
with
objective
to
measure
displacement
strain
during
cardiac
cycle.
Our
relies
regularized
deformable
image
registration
estimating
displacement,
estimation
local
as
ratio
its
normal
radius
curvature,
surface
fitting
non-deterministic
outlier
detection
curvature.
We
verified
our
against
synthetic
ground
truth
data
created
by
warping
a
3D-CTA
realistic
field
obtained
from
finite
element
biomechanical
model.
applied
assess
displacements
strains
ten
patients.
results
indicated
99th
percentile
circumferential
strain,
among
all
patients,
ranged
2.62%
5.54%,
average
4.45%
standard
deviation
0.87%.
also
observed
are
significantly
lower
than
those
healthy
aorta.
work
demonstrates
registration-based
measurement
direction
is
sufficiently
accurate
reliably
estimate
these
displacements.
