Recent advances in magnesium alloys and its composites for bioimplant applications: Processing, matrix, reinforcement, and corrosion perspectives

Critical reviews in solid state and materials sciences/CRC critical reviews in solid state and materials sciences, Год журнала: 2024, Номер unknown, С. 1 - 42

Опубликована: Март 25, 2024

Magnesium alloys have received a lot of attention as prospective bioimplant material due to their biocompatibility, mechanical properties, and biodegradability. composites hold enormous promise replacement for permanent metallic implants, there is no need secondary surgeries after recovery. To address the corrosion biodegradation rate magnesium, different approaches can be adopted, such composite preparation surface modification. This comprehensive review emphasizes processing route, matrix, reinforcement Mg alloy composite, with aim enhancing mechanical, biological, chemical properties. It also discusses biocompatibility aspects composites. The article sheds light on potential magnesium become dominant player in field materials.

Язык: Английский

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Current status and recent advances in magnesium-matrix syntactic foams: Preparation, mechanical properties, and corrosion behavior

Journal of Materials Research and Technology, Год журнала: 2024, Номер 30, С. 8316 - 8344

Опубликована: Май 1, 2024

Over the last ten years, magnesium (Mg)-based syntactic foams (SFs) have gained significant attention and their popularity continues to grow. This is because they possess unique properties such as high mechanical strength are lightweight, making them potential candidates for applications in various industries, including aerospace, automotive, biomedical (especially orthopedics). article reviews discusses different fabrication techniques used producing magnesium-matrix (Mg-MSFs). These include stir casting, disintegrated melt deposition, powder metallurgy, infiltration. The review comprehensively analyzes microstructure specifications, properties, corrosion behavior exhibited by Mg-MSFs fabricated date. findings suggest that of these foams, microstructural characteristics, behavior, significantly influenced factors filler particle amounts Mg alloy-matrix techniques, process parameters, post-processing treatments (such annealing sintering). play a crucial role determining final characteristics foams. While hold substantial importance potential, limited body research exists this area. Therefore, more necessary understand structures, which will facilitate effective utilization both industrial applications.

Язык: Английский

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Multifunctional rare earth oxide/MBG composite microspheres as a carrier for bone tumor treatment

Journal of Alloys and Compounds, Год журнала: 2024, Номер 993, С. 174603 - 174603

Опубликована: Апрель 22, 2024

Язык: Английский

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Advanced polymer composites and polymer hybrids for cartilage tissue engineering

Polymer Composites, Год журнала: 2024, Номер unknown

Опубликована: Июнь 4, 2024

Abstract The repair and regeneration of cartilage is a challenge for scientists clinical surgery. Achieving cell adhesion regeneration, anti‐inflammatory, lubrication, targeted drug delivery controlled release simultaneously in treatment are the goals researchers. Polymer composites hybrids have potential to realize above functions tissue engineering. This review refers injuries, current techniques, their benefits limitations, focusing on most relevant state art advanced polymers frontier applications multifunctional polymer engineering discussed depth, including scaffold, bio‐lubricant, zwitterionic sustained release. A summary comprehensive properties such as processability, mechanical properties, biocompatibility, biodegradability, hydrophilicity, cytotoxicity, etc., mechanisms analyzed. Furthermore, some key challenges outstanding concerns polymer‐based materials presented followed by future perspectives. Highlights bionic property mechanism hybrids. Polymers biolubricant, delivery, Future perspectives composites, hybrids‐based materials.

Язык: Английский

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Study of Nanohydroxyapatite Coatings Prepared by the Electrophoretic Deposition Method at Various Voltage and Time Parameters

Materials, Год журнала: 2024, Номер 17(10), С. 2242 - 2242

Опубликована: Май 10, 2024

The aim of the work is to compare properties nanohydroxyapatite coatings obtained using electrophoretic deposition method (EDP) at 10 V, 20 and 30 with deposit times 2 5 min. primary sedimentation was used minimize risk formation particle agglomerates on sample surface. Evaluation coating performed by a Scanning Electron Microscope (SEM), Energy-Dispersive Spectroscopy (EDS), Atomic Force Microscopy (AFM), optical profilometer, drop shape analyzer, nanoscratch tester. All are homogeneous without any agglomerates. When low voltage (10 V) used, were uniform continuous regardless time. increase in resulted cracks coatings. wettability test shows hydrophilic behavior mean contact angle values range 20-37°. showed excellent adhesion substrate. application maximum force 400 mN did not cause delamination most It concluded that optimal for orthopedic implants (such as hip joint implants, knee or facial elements) V min because its homogeneity, promotes osseointegration great

Язык: Английский

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Effects of hydroxyapatite content on cytotoxicity, bioactivity and strength of metakaolin/hydroxyapatite composites

Arabian Journal of Chemistry, Год журнала: 2024, Номер 17(9), С. 105878 - 105878

Опубликована: Июнь 15, 2024

The development of new materials is a critical challenge in advancing bone repair technology. Nowadays, the use high strength geopolymers extended to various fields, including biomedical research. This study investigates influence hydroxyapatite (HAp) content on vitro properties and characteristics metakaolin/HAp (MK/HAp) composites for potential application as substitutes. MK/HAp with varying HAp contents were fabricated subjected cytotoxicity, bioactivity, physical mechanical testing. PrestoBlue assay results confirmed acceptable osteoblast cell compatibility all composites, viability increases increasing content. Simulated body fluid (SBF) immersion demonstrated enhanced bioactivity bone-like apatite formation composite surfaces compressive decreased mainly due reduced amount silica alumina increased porosity higher HAp. Based present results, relationship between variations indicates promising composite. substitute material should be 50% or match specific human bones.

Язык: Английский

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Ultrasonic-Assisted Electrodeposition of Cu-TiO₂ Nanocomposite Coatings with Long-Term Antibacterial Activity

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(48), С. 66695 - 66705

Опубликована: Ноя. 19, 2024

Bacterial adhesion, colonization, and spread on aluminum alloy surfaces pose significant risks to human health public safety. To address these issues, this investigation employed an ultrasonic-assisted electrodeposition method synthesize long-lasting antibacterial Cu-TiO2 nanocomposite coatings porous anodized oxide (AAO) substrates. Leveraging the cavitation effect of ultrasound, approach fostered dispersive incorporation TiO2 nanoparticles into resulting composite coating, thereby expediting crystallization process refining granular structure. With optimal concentration 4 g/L nanoparticles, resultant C-4T coating displayed a dense homogeneous microstructure, with predominantly localized at grain boundaries Cu grains. Rigorous testing revealed that surface sample maintained enduring efficacy 96.8%, even after outer layer was worn away. This high level durability stems from continuous release ions reactive oxygen species (ROS) coating's region (CR) composed AAO film Cu-TiO2. The film, serving as "nanocontainers," offers ideal deposition carrier for uniform coating. These agents actively disrupt integrity chemical composition Escherichia coli (E. coli) cells, leading bacterial cell damage death, conferring superior persistent effects specific polishing. study advances field durable treatments opens avenues sanitary use in medical sectors.

Язык: Английский

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Advanced ultrasounds-assisted natural deep eutectic solvents green strategy for the sustainable extraction of biocompatible nano-hydroxyapatite from fish scales

Journal of Molecular Liquids, Год журнала: 2025, Номер unknown, С. 127515 - 127515

Опубликована: Апрель 1, 2025

Язык: Английский

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ZnO and Cu/ZnO-modified Magnesium orthopedic implant with improved osteoblast cellular activity: An in-vitro study

Journal of Materials Research and Technology, Год журнала: 2023, Номер 28, С. 935 - 950

Опубликована: Дек. 7, 2023

Mg-based biomaterials, due to their desirable mechanical integrity, natural bioabsorbability, and osteopromotive characteristics, are promising candidates for both orthopedic applications, such as the surgical fixation of injured musculoskeletal tissues, cardiovascular applications like coronary artery stents. In present study, nano- micro-sized ZnO Cu/ZnO bioactive fatparticles were used fabricate biocomposites using friction stir processing (FSP). FSP resulted in significant microstructural modification terms grain refinement, uniform redistribution secondary phase particles homogenous dispersion particles. Long-term biodegradation results through H2 evolution method illustrated that rate bioabsorbable WE43 alloy was significantly reduced by addition addition, fabricated with nano-sized lower comparison those Furthermore, superior in-vitro biocompatibility contact MC3T3-E1 mouse osteoblast cells. Mg–ZnO–N Mg–Cu/ZnO–N showed improved cell adhesion elongated spread morphology Live/dead staining MTT assay indicated number healthy cells viability after 24 h incubation increased distribution Moreover, Zn2+ Cu2+ ions higher ALP activity. Our findings propose Mg–ZnO Mg–Cu/ZnO can be bone tissue regeneration applications.

Язык: Английский

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UCNPs-labeled electrospun scaffolds used to monitor in vivo degradation and bone tissue regeneration

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 237, С. 113860 - 113860

Опубликована: Март 20, 2024

Biodegradable electrospun bone repair materials are effective means to treat defects. However, because the substrates mostly organic polymer materials, there is a lack of real-time and intuitive monitoring methods for their degradation in vivo. Therefore, it great significance develop vivo traced postoperative observation degradation. In this research, polycaprolactone/up-conversion nanoparticles/magnesium oxide (PCL/UCNPs/MgO) composite scaffolds were prepared by based on luminescence characteristics up-conversion nanoparticles (UCNPs) under near infrared excitation osteogenic ability MgO. The vitro results showed that with increase time, gradually degraded its intensity decreased. addition UCNPs can effectively monitor scaffolds. addition, had biocompatibility, among which PCL-1%UCNPs-1%MgO (P1U1M) obvious effect promoting differentiation mouse embryonic osteoblasts cells (MC3T3-E1) vitro. conclusion, P1U1M have potential induce regeneration at defect sites, It may be candidate material area.

Язык: Английский

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