Journal of Energy Storage, Год журнала: 2024, Номер 104, С. 114553 - 114553
Опубликована: Ноя. 15, 2024
Язык: Английский
Annals of 3D Printed Medicine, Год журнала: 2024, Номер 15, С. 100159 - 100159
Опубликована: Июнь 22, 2024
Three-dimensional (3D) bioprinting technology allows the production of porous structures with complex and varied geometries, which facilitates development equally dispersed cells orderly release signal components. This is in contrast to traditional methods used produce tissue scaffolding. To date, 3D has employed a range cell-laden materials, including organic synthetic polymers, construct scaffolding systems manufacture extracellular matrix (ECM). Still, there are several challenges meeting technical issues bio-ink formulations, such as printability bio-inks, customization mechanical biological properties bio-implants, guidance cell activities biomaterials, etc. The main objective this article discuss various strategies for preparing bio-inks mimic native tissue's environment. A discussion also been conducted about process parameters formulations printing, structure requirements, fabrication durable bio-scaffolds. present study reviews 3D-printing techniques. Conclusively, potential paths smart bioink/scaffolds have outlined regeneration.
Язык: Английский
Процитировано
17
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(14), С. 7810 - 7810
Опубликована: Июль 17, 2024
Nowadays, as a result of the frequent occurrence accidental injuries and traumas such bone damage, number people causing or fractures is increasing around world. The design fabrication ideal tissue engineering (BTE) materials have become research hotspot in scientific community, thus provide novel path for treatment diseases. Among used to construct scaffolds BTE, including metals, bioceramics, bioglasses, biomacromolecules, synthetic organic polymers, etc., natural biopolymers more advantages against them because they can interact with cells well, polymers be widely studied applied field BTE. In particular, alginate has excellent biocompatibility, good biodegradability, non-immunogenicity, non-toxicity, wide sources, low price, easy gelation, enabling itself biomaterial. However, pure hydrogel BTE scaffold material still many shortcomings, insufficient mechanical properties, disintegration physiological environments, lack cell-specific recognition sites, which severely limits its clinical application order overcome defects single hydrogels, researchers prepared composite hydrogels by adding one matrix certain proportion improve their bioapplicability. For this reason, review will introduce detail methods constructing alginate/polymer alginate/bioprotein polypeptide alginate/bioceramic alginate/nanoclay well biological trends materials, look forward future direction. These exhibit both unexceptionable biochemical high value repair regeneration, providing theoretical basis development sustainable alginate-based functional biomedical materials.
Язык: Английский
Процитировано
17
Small Structures, Год журнала: 2025, Номер unknown
Опубликована: Янв. 28, 2025
The increasing demand of advanced biomedical materials for bone repair and regeneration has spurred significant research in recent years. While traditional hydrogels offer promising biocompatibility easy fabrication, their application reconstruction is often impeded by inadequate structural integrity biological functions. Graphene oxide (GO) emerged as a transformative additive, renowned its exceptional mechanical chemical properties, well ability to enhance the hydrogels. In this study, incorporation GO into chitosan (CS) investigated, achieving bioinspired with enhanced strength stability, which are crucial supporting regeneration. Additionally, self‐assembled synthetic peptide nanofibers (PNFs) employed facilitate biomimetic mineralization hydrogels, critical process effective remodeling. This innovative composite hydrogel not only achieves but also exhibits osteogenic, pro‐angiogenic, antioxidant properties essential repair. novel method takes advantage distinctive GO, PNFs, biomass providing robust material solution potential significantly advance field tissue engineering.
Язык: Английский
Процитировано
1
Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 156498 - 156498
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
6
Nanomaterials, Год журнала: 2024, Номер 14(13), С. 1126 - 1126
Опубликована: Июнь 29, 2024
Phase change materials (PCMs) are that exhibit thermal response characteristics, allowing them to be utilized in the biological field for precise and controllable temperature regulation. Due considerations of biosafety spatial limitations within human tissue, amount PCMs used medical applications is relatively small. Therefore, researchers often augment with various enhance their performance increase practical value. The dispersion nanoparticles modify thermophysical properties has emerged as a mature concept. This paper aims elucidate role nanomaterials addressing deficiencies enhancing PCMs. Specifically, it discusses methods stabilization mechanisms PCMs, well effects on such conductivity, latent heat, specific heat capacity. Furthermore, explores how nano-additives contribute improved conductivity underlying enhanced heat. Additionally, potential biomedical fields proposed. Finally, this provides comprehensive analysis offers suggestions future research maximize utilization applications.
Язык: Английский
Процитировано
5
Journal of Materials Research and Technology, Год журнала: 2024, Номер 33, С. 7391 - 7405
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
4
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 585 - 656
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Advanced Functional Materials, Год журнала: 2025, Номер unknown
Опубликована: Май 6, 2025
Abstract Flexible electronics are of great interest in wearable bioelectronics, biomedicine, and robotics, with hydrogel emerging as an ideal candidate due to its excellent biocompatibility, stretchability, flexibility, making it suitable for applications electronics, clinical medicine, soft robotics. However, traditional hydrogels limited by restricted application scenarios, poor controllability, insufficient smart responsiveness. In contrast, phase transition hydrogels, characterized their reversible properties multifunctional adaptability, represent a promising advancement flexible electronics. This review systematically examines the various reaction types detailing underlying mechanisms materials involved. Furthermore, principles optical devices analyzed. Additionally, roles thermal management robotics explored. Finally, prospects challenges hydrogel‐based discussed, emphasizing need further optimization molecular structure cross‐linking system design, precise tuning temperature rate, enhancement long‐term stability, seamless integration conventional silicon‐based
Язык: Английский
Процитировано
0
Polysaccharides, Год журнала: 2025, Номер 6(2), С. 43 - 43
Опубликована: Май 23, 2025
The multifactorial modification of the structure and properties alginate matrix was conducted using partially acetylated cellulose nanocrystals. Fourier-transform infrared spectroscopy thermogravimetric analysis indicated absence chemical interactions between polymer filler. surface texture examined optical microscopy scanning electron microscopy, along with a reconstruction its 3D model. With an increase in content nanoparticles composite, following revealed. Firstly, roughness density arrangement elements increased, while their size decreased. Secondly, at pH values < 7, puncture resistance whereas swelling coefficient films In Hanks solutions, low solubility established, as well higher > 7. Thirdly, contribution donor centers to free energy, cytocompatibility composite films, adhesion fibroblasts increased. hematological tests composites showed procoagulant effect. Summarizing data, we propose model that explains influence nanocrystals concentration on formation observed composites’ physicochemical biological properties. main driving forces structurization are factor excluded volume heterogeneous colloidal system.
Язык: Английский
Процитировано
0
Gels, Год журнала: 2025, Номер 11(6), С. 426 - 426
Опубликована: Июнь 1, 2025
Multifunctional hydrogels represent an emerging technological advancement in cancer therapeutics, integrating diagnostic imaging capabilities with therapeutic modalities into comprehensive, multifunctional systems. These exhibit exceptional biocompatibility, biodegradability, high water retention capacity, and tunable mechanical properties, enabling precise drug delivery while minimizing systemic side effects. Recent innovations stimuli-responsive components facilitate intelligent, controlled release mechanisms triggered by various stimuli, including changes pH, temperature, magnetic fields, near-infrared irradiation. Incorporating agents, such as nanoparticles, fluorescent dyes, radiolabeled isotopes, substantially improves tumor visualization real-time monitoring. effectively integrate chemotherapy, photothermal therapy, photodynamic immunotherapy, their synergistic combinations, demonstrating superior outcomes compared to conventional methods. Particularly, injectable situ-forming provide sustained local postoperatively, reducing recurrence. However, challenges persist, initial burst release, instability, regulatory barriers, scalability concerns. Current research emphasizes advanced nanocomposite formulations, biofunctionalization strategies, innovative manufacturing technologies like 3D bioprinting clinical translation. This review comprehensively summarizes recent advancements, applications, future perspectives of hydrogel systems for enhanced treatment, underscoring potential revolutionize personalized oncology.
Язык: Английский
Процитировано
0