Ceramics International, Год журнала: 2024, Номер unknown
Опубликована: Дек. 1, 2024
Язык: Английский
Molecules, Год журнала: 2024, Номер 29(5), С. 1172 - 1172
Опубликована: Март 6, 2024
Implant-associated infections (IAIs) represent a major health burden due to the complex structural features of biofilms and their inherent tolerance antimicrobial agents immune system. Thus, viable options eradicate embedded on medical implants are surgical operations long-term repeated antibiotic courses. Recent years have witnessed growing interest in development robust reliable strategies for prevention treatment IAIs. In particular, it seems promising develop materials with anti-biofouling antibacterial properties combating IAIs implants. this contribution, we exclusively focus recent advances modified functionalized implant surfaces inhibiting bacterial attachment eventually biofilm formation orthopedic Further, highlight progress coatings (including self-assembled nanocoatings) preventing Among recently introduced approaches efficient durable coatings, use safe biocompatible excellent activities local delivery combinatorial treating overcoming resistance.
Язык: Английский
Процитировано
21
Microbiological Research, Год журнала: 2024, Номер 282, С. 127656 - 127656
Опубликована: Фев. 28, 2024
Язык: Английский
Процитировано
14
Small, Год журнала: 2024, Номер 20(46)
Опубликована: Авг. 19, 2024
Titanium and titanium alloys remain the gold standard for dental orthopedic implants. These materials are heavily used because of their bioinert nature, robust mechanical properties, seamless integration with bone. However, implant-associated infections (IAIs) one leading causes implant failure. Eradicating an IAI can be difficult since bacteria form biofilms on medical implant, protecting bacterial cells against systemic antibiotics host's immune system. If infection is not treated promptly aggressively, device failure inevitable, to costly multi-step revision surgeries. To circumvent this dire situation, scientists engineers continue develop novel strategies protect surface implants from bacteria. In review, details emerging prevent in reported. include anti-adhesion properties provided by polymers, superhydrophobic, superhydrophilic, liquid-infused coatings, as well coatings employed lyse Additionally, commercially available technologies those under preclinical trials examined while discussing current future trends.
Язык: Английский
Процитировано
11
Nanoscale Horizons, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
This review discusses commonly used semiconductor photocatalytic antibacterial materials, methods for improving their photocatalysis performance and application bone infection treatment.
Язык: Английский
Процитировано
1
Biomaterials Science, Год журнала: 2024, Номер 12(17), С. 4471 - 4482
Опубликована: Янв. 1, 2024
Hydrophilic antifouling coatings based on zwitterionic polymers have been widely applied for the surface modification of bone implants to combat biofilm formation and reduce likelihood implant-related infections. However, their long-term effectiveness is significantly limited by lack effective precise antibacterial activity. Here, a pH-responsive smart coating (PSB/GS coating) was designed robustly fabricated onto titanium-base using facile two-step method. First, dopamine (DA) poly(sulfobetaine methacrylate-
Язык: Английский
Процитировано
4
Progress in Organic Coatings, Год журнала: 2025, Номер 201, С. 109132 - 109132
Опубликована: Фев. 13, 2025
Язык: Английский
Процитировано
0
ACS Applied Bio Materials, Год журнала: 2025, Номер unknown
Опубликована: Фев. 17, 2025
Recent investigations have demonstrated that opportunistic fungi, such as Candida albicans, are associated with the contamination of implantable devices, biofilm formation, and consequent resistance to antimicrobial treatment. Preventing formation on device surfaces represents a significant challenge in medicine dentistry. This study aimed evaluate effects cold atmospheric plasma (CAP) treatment Ti-6Al-4V alloy surfaces, sterilized an autoclave at 120 °C for 20 min surgical-grade paper packaging, focusing their potential optimize surface physicochemical properties reduce C. albicans colonization. X-ray photoelectron spectroscopy (XPS) revealed Ti–O–H peaks oxidation titanium (Ti3+ Ti4+) CAP-treated surfaces. Sessile drop tests improvement wettability, reduction contact angle (68.94° vs 36.1°, p < 0.05). Microbiological assays showed colony-forming units (CFUs) (42,500 ± 8,838 24,000 7,920; 0.05) decrease pseudohyphae (32.7 9.7 11.6 1.8; Scanning electron microscopy (SEM) further confirmed yeast aggregates treated incubated fungal strains 90 min. Data normality was assessed using Shapiro-Wilk test, statistical comparisons were performed t significance level 0.05. These findings suggest CAP is promising tool enhancing wettability reducing implants sealed paper, offering benefits medical dental applications.
Язык: Английский
Процитировано
0
International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141862 - 141862
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Progress in Organic Coatings, Год журнала: 2024, Номер 196, С. 108706 - 108706
Опубликована: Авг. 5, 2024
Язык: Английский
Процитировано
3
Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 245, С. 114208 - 114208
Опубликована: Сен. 3, 2024
Язык: Английский
Процитировано
2