Ceramics International, Год журнала: 2024, Номер unknown
Опубликована: Дек. 1, 2024
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136481 - 136481
Опубликована: Окт. 9, 2024
Язык: Английский
Процитировано
2
Advanced Functional Materials, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 25, 2024
Abstract The infected chronic wound area has a unique microenvironment featuring hypoxia, excessive reactive oxygen species (ROS), and inflammatory conditions. Bacteria‐formed biofilms limit the anti‐inflammation efficiency of most therapeutics by hindering their penetration into deep tissues increasing drug resistance. unitary modulation pro‐inflammatory M1 macrophage polarization cannot relieve inflammation immediately. Here, “all in one” folic acid‐modified small organic molecule‐based nanoparticles (2TT‐ m C6B@CeO 2 @FA, PCFs) are developed, which possess dual‐targeting to bacteria macrophages, double photothermal therapy (PTT), enzymatic‐like activities. Based on considerable catalase‐ superoxide dismutase‐like activities, PCFs can efficiently scavenge ROS produce (O ). generated O automatically drive movement as nanomotors further promote rescue hypoxia. scavenging promotes macrophages polarized anti‐inflammatory M2 macrophages. study also identifies that FA‐modified target selectively eliminate through PTT, relieves healing. Transcriptome analysis confirms inhibit expression inflammatory‐related genes while cytokines. In vivo experiments identify benefit neovascularization neonatal tissue generation at sites.
Язык: Английский
Процитировано
1
Ceramics International, Год журнала: 2024, Номер 50(11), С. 20561 - 20572
Опубликована: Март 14, 2024
Язык: Английский
Процитировано
1
New Journal of Chemistry, Год журнала: 2024, Номер 48(25), С. 11465 - 11475
Опубликована: Янв. 1, 2024
A good biocompatible multifunctional Ti implant was constructed, which exhibits synergistic antibacterial activity through photothermal and NO effects, promotes osseointegration.
Язык: Английский
Процитировано
1
Surfaces and Interfaces, Год журнала: 2024, Номер 51, С. 104776 - 104776
Опубликована: Июль 11, 2024
Язык: Английский
Процитировано
1
Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 245, С. 114249 - 114249
Опубликована: Сен. 16, 2024
Язык: Английский
Процитировано
1
Опубликована: Авг. 6, 2024
Achieving the best aesthetic result is a key objective of implant-prosthetic therapy. To maximize outcome, ensuring that implant-supported restorations are in harmony with peri-implant soft tissues and bone essential. A comparative analysis zirconia titanium dental implants revealed both materials offer high success rates; however, they present distinct advantages limitations clinical practice. Titanium implants, surface modifications but without chemical composition changes, boast remarkable long-term survival. In contrast, while presenting biocompatibility qualities, have relatively incidence material-specific failure, ranging from 4% to 2% after 5-10 years. While generally show superior performance, benefit ongoing advancements aimed at improving their osseointegration longevity. This study emphasizes need for short-term studies, complemented by randomized controlled trials (RCTs), which essential optimizing implant patient satisfaction. Continued innovation research crucial advancing technology enhancing quality life patients requiring restorations. Finally, it important understand all disadvantages, so choice optimal material should be based on specific purpose.
Язык: Английский
Процитировано
0
Ceramics International, Год журнала: 2024, Номер unknown
Опубликована: Дек. 1, 2024
Язык: Английский
Процитировано
0