Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2024, Номер unknown, С. 136091 - 136091
Опубликована: Дек. 1, 2024
Язык: Английский
Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2024, Номер unknown, С. 136091 - 136091
Опубликована: Дек. 1, 2024
Язык: Английский
European Polymer Journal, Год журнала: 2024, Номер 215, С. 113251 - 113251
Опубликована: Июнь 19, 2024
Meeting the escalating demands in biomedical applications has spurred creation of diverse scaffolds, where selection materials and manufacturing techniques stands as a linchpin fostering bone tissue formation. These scaffolds provide fundamental structural framework that supports cell growth differentiation. It is vital for repair, addressing various biological requisites such biocompatibility, biodegradability, mechanical properties becomes imperative. This comprehensive review discusses recent advancements 3D tailored specifically engineering applications. Stereolithography, fused deposition modelling, selective laser sintering, binder jetting, electron beam melting, bioprinting (including laser-based, inkjet extrusion bioprinting) are meticulously explored. Focusing on their respective applications, limitations, well advantages disadvantages within context regeneration. Furthermore, article underscores pivotal role material potential solution to address challenges associated with grafts. emphasizes need nuanced understanding significant considerations regardless type when designing or evaluating suitability integration into expansive realm engineering.
Язык: Английский
Процитировано
25Advanced Engineering Materials, Год журнала: 2024, Номер unknown
Опубликована: Сен. 8, 2024
This study is initiated with the aim of regulating release silver (Ag) as an antibacterial agent from micro‐arc oxidation (MAO) coating. Herein, external 5 wt% Tin(II) chloride (SnCl 2 ) containing biodegradable polycaprolactone (PCL) layer formed on 0.8 Ag‐incorporated MAO coating by dip method. SnCl addition into PCL provides a steady Ag concentrated simulated body fluid (1.5X SBF) underlying at 37 °C. When rate taken consideration, it quantified 0.0089 and 0.0586 ppm day −1 for PCL‐covered PCL‐free coatings, respectively. It finally concluded that preliminary result this can be promising minimizing in vivo adverse effects + ions arising rapid well maintaining efficacy prolonged periods, which ideal preventing risk postimplantation infections.
Язык: Английский
Процитировано
5Biomedical Materials, Год журнала: 2024, Номер 20(1), С. 012001 - 012001
Опубликована: Ноя. 22, 2024
Abstract Advancement in medicine and technology has resulted into prevention of countless deaths increased life span. However, it is important to note that, the modern lifestyle altered food habits, witnessed life-style stresses road accidents leading several health complications one primary victims bone health. More often than ever, healthcare professionals encounter cases massive fracture, loss generation critical sized defects. Surgical interventions, through use grafting techniques are necessary such cases. Natural grafts (allografts, autografts xenografts) however, have major drawbacks terms delayed rehabilitation, lack appropriate donors, infection morbidity that shifted focus investigators direction synthetic grafts. By employing biomaterials based on tissue engineering (BTE), provide a more biologically acceptable approach establishing phases healing. In BTE, various materials utilized support enhance regeneration. Biodegradable polymers like poly-(lactic acid), poly-(glycolic poly-( ϵ -caprolactone) commonly used for their customizable mechanical properties ability degrade over time, allowing natural growth. PEG employed hydrogels promote cell adhesion Ceramics, as hydroxyapatite beta-tricalcium phosphate ( β -TCP) mimic mineral attachment, with -TCP gradually resorbing new forms. Composite materials, including polymer-ceramic polymer-glasses, combine benefits both ceramics/glasses offer enhanced biological properties. collagen, gelatin, chitosan matrix attachment formation, also offering antimicrobial Hybrid decellularized retain structure factors, while functionalized scaffolds incorporate growth factors or bioactive molecules further stimulate healing integration. The current review article provides insights could yield revolutionary improvements orthopedic medical fields. introduction section this focuses statistical information requirements globally its impact economy. later section, anatomy human bone, defects diseases pertaining limitations were detailed. Biopolymers, bioceramics, biometals-based discussed depth sections followed. then concludes summary addressing trends future prospects potential transplants.
Язык: Английский
Процитировано
5International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136481 - 136481
Опубликована: Окт. 9, 2024
Язык: Английский
Процитировано
4Опубликована: Янв. 1, 2025
The repair of bone graft defects remains a challenging clinical issue, often accompanied by the risk infection in grafted area. To address this, we have developed novel GO-CS@ZnO composite material specifically designed for defect repair. key innovation this study lies successful synthesis and characterization material, which exhibits excellent antibacterial properties favorable biocompatibility. was synthesized using water bath method characterized XRD, FT-IR, XPS, SEM. material's hydrophilic confirmed through contact angle measurements. Rigorous testing demonstrated its strong properties, while cytotoxicity tests further good These findings highlight significant potential field repair, offering promising new approach to addressing challenge.
Язык: Английский
Процитировано
0Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Journal of Magnesium and Alloys, Год журнала: 2025, Номер unknown
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0Ceramics International, Год журнала: 2025, Номер unknown
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0Polymer Composites, Год журнала: 2025, Номер unknown
Опубликована: Июнь 2, 2025
ABSTRACT Carbon fiber composites are considered ideal candidates for orthopedic implants due to their elastic modulus being similar that of human bone, but the interfacial bonding between carbon fibers and matrix is still a challenge. In this work, multiscaled calcium phosphate dihydrate nanosheets/microsheets (CHPDnm) introduced on surface by one‐step pulsed electrodeposition method (PED), which significantly improves mechanical biofriction properties composites. CHPD nanosheets grow in situ fibers, fiber/matrix interface bonding. microsheets extend into enhance cohesion matrix. The improved synergistic effect microsheets. Compared pristine composites, flexural compressive strength CHPDnm‐reinforced epoxy resin/phenolic resin/pyrolytic (CHPDnm‐CE, CHPDnm‐CP, CHPDnm‐CC) enhanced 18.1%, 118.31%, 218.0% 53.3%, 32.33%, 41.3%, respectively. addition, CHPDnm‐CE, CHPDnm‐CC showed reduction 80.5%, 50.0%, 21.6% wear rate. This work provides practical strategy modification while broadening application as implants.
Язык: Английский
Процитировано
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