WHIGET and TETRAS Ratings of Action Tremor in Patients with Essential Tremor: Substantial Association and Agreement

Tremor and Other Hyperkinetic Movements, Год журнала: 2024, Номер 14, С. 14 - 14

Опубликована: Март 27, 2024

Background: Evaluating tremor severity is a critical component of diagnosing and clinically managing patients with essential (ET). We examined the comparability ratings derived from two frequently used rating scales: Washington Heights-Inwood Genetic Study Essential Tremor (WHIGET) scale Research Group Rating Scale (TETRAS). Methods: A trained assistant administered videotaped neurological examination, including eight items assessing upper limb action (arms outstretched, arms in wingbeat position, finger-nose-finger maneuver, drawing Archimedes spirals). An experienced movement disorders neurologist reviewed videos assigned WHIGET TETRAS ratings. calculated associations between using Spearman rank order correlations. Subsequently, we collapsed these into four categories (absent, mild, moderate, severe) then broader (absent/mild, moderate/severe). weighted Kappa coefficients to assess agreement category assignments based on WHIGET. Results: Spearman’s r’ s were significant for all (p’s ≤ 0.001, mean r = 0.89). Weighted Kappa’s revealed substantial near perfect (mean k 0.86, range 0.64 1.00). Conclusion: Analyses strength association rated scales. These data indicated that provided by each are highly comparable.

Язык: Английский

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Audible Tremor: Analysis of the Validity of Audible Information in Assessing Tremor Severity

Parkinsonism & Related Disorders, Год журнала: 2025, Номер 132, С. 107291 - 107291

Опубликована: Янв. 17, 2025

Язык: Английский

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Baseline Depressive Symptoms as a Predictor of Incident Dementia in a Prospectively Followed Cohort of Elders with Essential Tremor

Neurodegenerative Diseases, Год журнала: 2024, Номер 24(2), С. 80 - 90

Опубликована: Июль 9, 2024

Introduction: Essential tremor (ET) patients may exhibit a variety of non-motor features, including cognitive decline and depressive symptoms. Studies several neurodegenerative diseases link depression to decline, suggesting is an early marker dementia. We examined whether baseline symptoms predict incident dementia in elders with ET. Methods: Hundred forty-one ET cases aged 70 years or older at baseline, enrolled prospective study performance, took part evaluations 18, 36, 54, 72 months. Participants completed the Geriatric Depression Scale (GDS), 30-item self-report measure symptoms, battery neuropsychological tests functional assessments, from which we derived diagnoses each evaluation. Cox proportional hazards regression equations determined risk based on participants’ scores. Results: Mean age was 81.5 ± 6.7 years. Higher GDS scores were associated increased unadjusted model (hazards ratio [HR] = 1.11, 95% confidence interval [CI] 1.02–1.20, p 0.01) after controlling for age, education, number medications, onset (HR 1.13, CI 1.02–1.25, 0.02). Conclusion: Baseline predicted With one-point increase score, there 13% risk. Given published data that reported be twice as high compared controls, this association particularly worrisome population.

Язык: Английский

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Cranial Tremors in Essential Tremor: Prevalence, Anatomic Distribution and Predictors of Occurrence

Movement Disorders Clinical Practice, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 8, 2024

There are few published data on the prevalence, pattern of anatomic distribution and predictors various cranial tremors (eg, head, voice, jaw) in essential tremor (ET). Given high levels diagnostic misclassification ET, observed clinical patterns would be valuable.

Язык: Английский

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