Variability in COVID-19 symptom presentation during pregnancy and its impact on maternal and infant outcomes across the pandemic
Julia Günther,
Yvonne Ziert,
Kristin Andresen
и другие.
International Journal of Infectious Diseases,
Год журнала:
2024,
Номер
146, С. 107157 - 107157
Опубликована: Июль 5, 2024
Язык: Английский
COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss
Human Reproduction Update,
Год журнала:
2023,
Номер
30(2), С. 133 - 152
Опубликована: Ноя. 28, 2023
Abstract
BACKGROUND
Pregnant
women
infected
with
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
are
more
likely
to
experience
preterm
birth
and
their
neonates
be
stillborn
or
admitted
a
neonatal
unit.
The
World
Health
Organization
declared
in
May
2023
an
end
the
disease
2019
(COVID-19)
pandemic
as
global
health
emergency.
However,
pregnant
still
becoming
SARS-CoV-2
there
is
limited
information
available
regarding
effect
of
infection
early
pregnancy
on
outcomes.
OBJECTIVE
AND
RATIONALE
We
conducted
this
systematic
review
determine
prevalence
loss
SARS-Cov-2
compare
risk
without
infection.
SEARCH
METHODS
Our
based
prospectively
registered
protocol.
search
PregCov19
consortium
was
supplemented
extra
electronic
specifically
up
10
March
PubMed,
Google
Scholar,
LitCovid.
included
retrospective
prospective
studies
infection,
provided
that
they
contained
losses
first
and/or
second
trimester.
Primary
outcome
miscarriage
defined
before
20
weeks
gestation,
however,
reported
22
24
were
also
included.
Additionally,
we
report
occur
at
trimester
specifying
gestational
age,
for
only
when
study
presented
stillbirths
foetal
separately
from
miscarriages.
Data
stratified
into
Secondary
outcomes
ectopic
(any
extra-uterine
pregnancy),
termination
pregnancy.
At
least
three
researchers
independently
extracted
data
assessed
quality.
calculated
odds
ratios
(OR)
differences
(RDs)
corresponding
95%
CI
pooled
using
random
effects
meta-analysis.
To
estimate
prevalence,
performed
meta-analysis
proportions.
Heterogeneity
by
I2.
OUTCOMES
120
comprising
total
168
444
infection;
which
18
233
Evidence
level
considered
low
moderate
certainty,
mostly
owing
selection
bias.
did
not
find
evidence
association
between
(OR
1.10,
0.81–1.48;
I2
=
0.0%;
RD
0.0012,
−0.0103
0.0127;
0%;
9
studies,
4439
women).
Miscarriage
occurred
9.9%
(95%
6.2–14.0%;
68%;
46
1797
women)
SARS
CoV-2
1.2%
0.3–2.4%;
34%;
33
studies;
3159
proportion
pregnancies
1.4%
0.02–4.2%;
66%;
14
950
Termination
0.6%
0.01–1.6%;
79%;
39
1166
WIDER
IMPLICATIONS
found
no
indication
increases
provide
better
estimates,
well-designed
needed
include
conception
consider
clinical
manifestation
severity
loss,
well
potential
confounding
factors
such
previous
loss.
For
practice,
should
advised
take
precautions
avoid
exposure
receive
vaccination.
Язык: Английский
Impact of COVID-19 on pregnant women's health: Consequences in obstetrics two years after the pandemic
Journal of Reproductive Immunology,
Год журнала:
2023,
Номер
158, С. 103981 - 103981
Опубликована: Июнь 15, 2023
Язык: Английский
Variantes de SARS CoV-2: Prevalencia y complicaciones en la población adulta
MQRInvestigar,
Год журнала:
2024,
Номер
8(1), С. 3040 - 3058
Опубликована: Фев. 26, 2024
Las
variantes
genéticas
del
SARS-CoV-2
han
estado
surgiendo
y
extendiéndose
por
todo
el
mundo.
La
región
de
las
Américas
ha
tenido
537.678
casos
confirmados;
representando
34,4
%
total
los
notificados
en
mundo
con
19
309
muertes
2020.
El
objetivo
esta
investigación
fue
analizar
la
prevalencia
complicaciones
población
adulta.
estudio
diseño
documental
carácter
descriptivo
corte
transversal
retrospectivo,
bases
datos
PubMed,
Scielo
Springer,
Google
Scholar,
ELSEVIER,
publicados
durante
últimos
5
años
idiomas
español,
inglés
portugués
a
partir
búsqueda
avanzada
términos
MeSH,
SARS-CoV-2,
COVID-19,
variantes,
adultos.
Entre
resultados
se
encontró
que
continente
asiático
predominaba
variante
ómicron,
americano
europeo
alfa
delta,
dichas
relacionaron
causas
neumonía
e
infecciones
maternas
más
graves,
ómicron
ataques
cardiacos
neumonía,
beta
insuficiencia
respiratoria
aguda.
afectaciones
salud
mental
depresión
ansiedad
tuvieron
mayor
impacto
tipo
desde
profesionales
hasta
personas
adultas
general.
Se
concluye
mostró
una
alta
asiático,
cada
está
asociada
diferentes
tipos
pacientes
infectados
COVID-19
su
adultos
puesto
manifiesto
serie
efectos
negativos
significativos
The Maternal Psychic Impact of Infection by SARS-CoV-2 during Pregnancy: Results from a Preliminary Prospective Study
Healthcare,
Год журнала:
2024,
Номер
12(9), С. 927 - 927
Опубликована: Апрель 30, 2024
Due
to
a
higher
risk
of
maternal
complications
during
pregnancy,
as
well
pregnancy
such
stillbirth,
SARS-CoV-2
contamination
is
putative
stress
factor
that
could
increase
the
perinatal
mental
health
issues.
We
included
women
older
than
18
years,
who
delivered
living
baby
at
Geneva
University
Hospitals’
maternity
wards
after
29
weeks
amenorrhea
(w.a.)
and
excluded
did
not
read
or
speak
fluent
French.
compared
declared
having
had
COVID-19,
confirmed
by
positive
PCR
test
for
SARS-CoV-2,
with
not,
both
delivery
one
month
postpartum.
collected
clinical
data
auto-questionnaires
between
time
childbirth
third
day
postpartum
regarding
occurrence
depression,
peritraumatic
dissociation,
distress
childbirth,
measured,
respectively,
EPDS
(depression
score
>
11),
PDI
(peritraumatic
15),
PDEQ
(scales).
At
postpartum,
we
proportion
diagnosis
depression
(PPD)
birth-related
posttraumatic
disorder
(CB-PTSD),
using
PCL-5
CB-PTSD
criteria
according
DSM-5
PPD
CB-PTSD,
in
context
semi-structured
interview,
conducted
clinician
psychologist.
Off
257
included,
Hospitals
25
January
2021
10
March
2022,
41
(16.1%)
they
their
pregnancy.
Regarding
outcomes,
except
PTSD,
all
scores
provided
mean
values
group
been
infected
without
reaching
any
statistical
significance:
7.8
(±5.2,
8:4–10.5)
versus
6.5
(±4.7,
6:3–9),
p
=
0.139
***,
continuous
scores;
(25.0)
45
(21.1),
0.586
*,
dichotomous
(≥11);
118
(55.7)
26
(63.4),
0.359
18.3
(±6.8,
16:14–21)
21.1
(±10.7,
17:15–22),
0.231
(≥15);
14.7
(±5.9,
13:10–16)
15.7
(±7.1,
14:10–18),
0.636
64
(30.0)
17
(41.5),
0.151
2
(8.0)
5
(3.6),
0.289
diagnosis,
DSM-5.
performed
Chi-squared
Fisher’s
exact
tests,
depending
on
applicability
comparison
categorical
variables
Mann–Whitney
nonparametric
tests
variables;
<
0.05
was
considered
statistically
significant.
Surprisingly,
find
more
PTSD
noted
SARS-CoV-2:15
(10.6)
no
case
birth
related
were
(p
0.131
*).
Our
study
showed
outcomes
differently
distributed
infected.
However,
our
underpowered
explore
factors
associated
psychiatric
issues
exposure
infection
Future
longitudinal
studies
bigger
samples
diverse
populations
over
longer
period
are
needed
long-term
psychic
impact
COVID-19
Язык: Английский
Eighteen-Month Outcomes Among Pregnant and Nonpregnant Reproductive-Aged People Hospitalized for Coronavirus Disease 2019
Open Forum Infectious Diseases,
Год журнала:
2024,
Номер
11(7)
Опубликована: Июнь 28, 2024
Abstract
Background
Physiologic
and
immunologic
adaptations
in
pregnancy
may
increase
the
risk
of
adverse
outcomes
from
respiratory
viral
infections.
However,
data
are
limited
on
longer-term
after
severe
acute
syndrome
coronavirus
2
(SARS-CoV-2)
infection
prior
to
widespread
vaccine
availability.
Methods
Using
electronic
health
record
data,
we
retrospectively
compared
6-,
12-,
18-month
including
death
rehospitalization
between
pregnant
nonpregnant
reproductive-aged
individuals
hospitalized
for
SARS-CoV-2
2020
2021
at
academic
referral
hospitals.
Results
There
were
190
70
participants.
Mean
age
was
31
years
34
For
patients,
mean
gestational
disease
2019
(COVID-19)
diagnosis
36
weeks,
54%
delivered
by
cesarean,
97%
a
live
birth.
Compared
participants,
participants
had
higher
prevalence
baseline
comorbidities
proportion
received
mechanical
ventilation
(84%
vs
55%).
Index
hospitalization
complications
(31%
17%)
mortality
(3%
0%)
more
common
Over
18
months
following
index
hospitalization,
39
(21%)
5
(7%)
readmitted,
most
(28/44
[64%]).
Most
readmissions
occurred
within
6
months.
no
posthospitalization
deaths
group.
Conclusions
Pregnant
people
with
COVID-19
low
rate
hospitalization.
The
readmission
is
reassuring
that
not
be
long-term
population,
possibly
because
any
increased
conferred
resolves
soon
delivery.
Язык: Английский
Impact of COVID-19 in pregnancy on maternal and perinatal outcomes during the Delta variant period: a comparison of the Delta and pre-delta time periods, 2020–2021
Maternal Health Neonatology and Perinatology,
Год журнала:
2024,
Номер
10(1)
Опубликована: Сен. 30, 2024
Язык: Английский