Optical and Quantum Electronics, Год журнала: 2024, Номер 57(1)
Опубликована: Дек. 2, 2024
Язык: Английский
Materials Today Bio, Год журнала: 2024, Номер 26, С. 101028 - 101028
Опубликована: Март 24, 2024
The expansion applications of semiconducting polymer dots (Pdots) among optical nanomaterial field have long posed a challenge for researchers, promoting their intelligent application in multifunctional nano-imaging systems and integrated nanomedicine carriers diagnosis treatment. Despite notable progress, several inadequacies still persist the Pdots, including development simplified near-infrared (NIR) nanoprobes, elucidation inherent biological behavior, integration information processing nanotechnology into biomedical applications. This review aims to comprehensively elucidate current status Pdots as classical nanophotonic material by discussing its advantages limitations terms biocompatibility, adaptability microenvironments vivo, etc. Multifunctional surface chemistry play crucial roles realizing Pdots. Information visualization based on physicochemical properties is pivotal achieving detection, sensing, labeling probes. Therefore, we refined underlying mechanisms constructed multiple comprehensive original mechanism summaries establish benchmark. Additionally, explored cross-linking interactions between nanomedicine, potential yet complete metabolic pathways, future research directions, innovative solutions integrating treatment strategies. presents possible expectations valuable insights advancing specifically from chemical, medical, photophysical practitioners' standpoints.
Язык: Английский
Процитировано
8
ACS ES&T Engineering, Год журнала: 2024, Номер 4(6), С. 1469 - 1478
Опубликована: Апрель 2, 2024
Optical detection techniques are frequently used in environmental monitoring due to their high sensitivity and stability; however, decrease the optical interferences from matrix remains challenging. Herein, dissolved organic matter (DOM), a surface-enhanced Raman scattering (SERS)-silent region (1800–2800 cm–1) sensor has been studied for of NO2– (a model pollutant) presence DOM. 4-Ethynylaniline (4-EA) was selected as sensing molecule. The signal band (2205 internal standard 4-EA (1985 SERS-silent quantitative analysis NO2–. Since can well avoid overlapping with DOM signal, dual-silent ratio I2205/I1985 exhibits outstanding anti-interference ability toward different common matter. Compared traditional UV–vis detection, this method maintains higher (with limit 10–7 M) better accuracy (detection recovery ranges 89.9 109.7%) real samples. Furthermore, SERS successfully employed an survey local river. These findings imply that nanosensor provides way develop accurate monitoring.
Язык: Английский
Процитировано
7
The Science of The Total Environment, Год журнала: 2024, Номер 931, С. 172848 - 172848
Опубликована: Май 3, 2024
Water contamination represents a significant ecological impact with global consequences, contributing to water scarcity worldwide. The presence of several pollutants, including heavy metals, pharmaceuticals, pesticides, and pathogens, in resources underscores pressing concern, prompting the European Union (EU) establish Watch List monitor level these substances. Nowadays, standard methods used detect quantify contaminants are mainly liquid or gas chromatography coupled mass spectrometry (LC/GC–MS). While methodologies offer precision accuracy, they require expensive equipment experienced technicians, cannot be on field. In this context, chalcogenide quantum dots (QDs)-based sensors have emerged as promising, user-friendly, practical, portable tools for environmental monitoring. QDs semiconductor nanocrystals that possess excellent properties, demonstrated versatility across various sensor types, such fluorescent, electrochemical, plasmonic, colorimetric ones. This review summarizes recent advances (2019–2023) use sensing, highlighting development capable efficiently anions, endocrine disrupting compounds, organic dyes, toxic gases, nitroaromatics, pathogens.
Язык: Английский
Процитировано
7
Talanta, Год журнала: 2024, Номер 273, С. 125873 - 125873
Опубликована: Март 4, 2024
Язык: Английский
Процитировано
6
Chemosensors, Год журнала: 2024, Номер 12(4), С. 58 - 58
Опубликована: Апрель 8, 2024
Pharmaceutical opioids are intravenously or orally administered analgesics. While they effective in relieving chronic and acute pain, their narrow window of therapeutic use contributes to the high occurrence abuse. The associated abuse this family drugs can be correlated increase dependency, overdose, death users. negative effects extend beyond physical psychological experienced by user unregulated synthesis sale, which contribute socioeconomic challenges a biproduct global public health epidemic. From clinical point-of-care applications, detection real-time monitoring drug is critical fight decrease improve settings. Chromatographic separations chromatography–mass spectrometry traditional methods opioid analyses, but cost, long analysis time, absence portability highlight need for development fast, situ, analysis, community services. This review highlights recent electrochemical optical (FTIR, Raman, colorimetric, fluorescent) advances biosensors pharmaceutical illicit analysis. Specifically, an emphasis placed on metabolites biological samples vitro cellular assays diagnosis forensic applications. prospects role sensors, biosensors, sensors promoting diagnosis, study, point-of-care, services reduce harm also provided.
Язык: Английский
Процитировано
6
Analytical and Bioanalytical Chemistry, Год журнала: 2024, Номер unknown
Опубликована: Июнь 6, 2024
Язык: Английский
Процитировано
6
Journal of Applied Physics, Год журнала: 2025, Номер 137(6)
Опубликована: Фев. 10, 2025
In this paper, we present a deep neural network model capable of simultaneously predicting the optical transmittance spectra three distinct gold nanostructures: nanodisks, truncated cones, and nanocones. Our achieved mean squared error loss as low 0.0015. By systematically varying geometric parameters, generated comprehensive dataset to train model, which captures complex dependencies between structure response. A key finding is redshift in resonance dip associated with increasing sidewall tilt. We further validated by comparing its predictions experimental results, showing excellent agreement. This work demonstrates powerful, data-driven approach for rapid design optimization plasmonic nanostructures, opening new possibilities nanophotonic applications.
Язык: Английский
Процитировано
0
Biosensors, Год журнала: 2024, Номер 14(1), С. 34 - 34
Опубликована: Янв. 10, 2024
Pap smear screening is a widespread technique used to detect premalignant lesions of cervical cancer (CC); however, it lacks sensitivity, leading identifying biomarkers that improve early diagnosis sensitivity. A characteristic the aberrant sialylation involves abnormal expression α2,6 sialic acid, specific carbohydrate linked glycoproteins and glycolipids on cell surface, which has been reported in CC lesions. This work aimed develop method differentiate lines primary fibroblasts using novel lectin-based biosensor acid based attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) chemometric. The was developed by conjugating gold nanoparticles (AuNPs) with 5 µg Sambucus nigra (SNA) lectin as biorecognition element. Sialic detection associated signal amplification 1500–1350 cm−1 region observed surface-enhanced absorption (SEIRA) effect from ATR-FTIR results. further analyzed for clustering samples applying principal component analysis (PCA) confidence ellipses at 95% interval. demonstrates feasibility employing SNA biosensors discriminate between tumoral non-tumoral cells, have potential CC.
Язык: Английский
Процитировано
4
BMC Chemistry, Год журнала: 2024, Номер 18(1)
Опубликована: Март 23, 2024
Abstract Gold and silver nanoparticles have witnessed increased scientific interest due to their colourful colloidal solutions exceptional applications. Comparing the localized surface plasmon resonance (LSPR) of gold is crucial for understanding optimizing optical properties. This comparison informs design highly sensitive plasmonic sensors, aids in selecting most suitable applications like surface-enhanced infrared spectroscopy (SEIRA) biomedical imaging, guides choice between based on catalytic photothermal Ultimately, study LSPR facilitates tailored use these diverse technological Two SEIRA methods combined with partial least squares regression (PLSR) chemometric tools were developed. development synthesis homogeneous, high-dense deposited metal nanoparticle islands over glass substrates be used as lab-on-chip sensors determination bisacodyl (BIS) its active metabolite plasma. SEM micrographs revealed formation metallic citrate-capped average sizes 29.7 15 nm, respectively. BIS placed nanoparticles’ coated directly measured, then PLSR modelling was quantitative determinations. Plasmonic showed better performance than those prepared using terms preparation time, enhancement factor, model prediction, results. offers a way determine concentration range 15–240 ng/mL human plasma inexpensive disposable glass-coated that can 1 h get results seconds good recovery 98.77 100.64%. The provided fast, simple, selective, molecular-specific procedures molecules pure form biological fluid.
Язык: Английский
Процитировано
4
Microchemical Journal, Год журнала: 2024, Номер 203, С. 110912 - 110912
Опубликована: Июнь 9, 2024
Язык: Английский
Процитировано
4