Industrial Crops and Products, Год журнала: 2024, Номер 222, С. 119949 - 119949
Опубликована: Ноя. 4, 2024
Язык: Английский
Industrial Crops and Products, Год журнала: 2024, Номер 222, С. 119949 - 119949
Опубликована: Ноя. 4, 2024
Язык: Английский
Polymer-Plastics Technology and Materials, Год журнала: 2024, Номер 64(4), С. 397 - 438
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
9Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Polymers for Advanced Technologies, Год журнала: 2025, Номер 36(4)
Опубликована: Апрель 1, 2025
ABSTRACT Smart polymeric micelles have emerged as versatile nanocarriers in targeted drug delivery, driven by their unique ability to encapsulate therapeutic agents and deliver them with precision specific sites. This review delves into the recent advancements design, functionality, biomedical applications of these nanostructures, emphasizing role enhancing efficacy while minimizing systemic toxicity. The begins discussing principles behind stimuli‐responsive micelles, exploring mechanisms triggered pH, redox conditions, temperature, light achieve controlled release. It highlights advances functionalization strategies, including surface modifications targeting ligands stimuli‐sensitive linkages, which enhance specificity adaptability pathological microenvironments. Subsequent sections focus on cutting‐edge applications, particularly cancer therapy, regenerative medicine, theranostics, showcasing potential addressing complex clinical challenges. Emerging technologies, such multi‐stimuli‐responsive systems hybrid are explored for overcome limitations loading, stability, release profiles. Despite significant progress, current technologies still face challenges, achieving consistent reproducible loading efficiencies, maintaining stability physiological environments, controlling precise kinetics, ensuring scalable cost‐effective production methods. concludes a discussion challenges future perspectives field, need integrating advanced polymer chemistry, nanotechnology, biomedicine develop next‐generation smart micelles. By providing comprehensive overview, this article aims underscore transformative advancing medicine interventions.
Язык: Английский
Процитировано
0Biomaterials, Год журнала: 2024, Номер 316, С. 123021 - 123021
Опубликована: Дек. 15, 2024
Язык: Английский
Процитировано
1Industrial Crops and Products, Год журнала: 2024, Номер 222, С. 119949 - 119949
Опубликована: Ноя. 4, 2024
Язык: Английский
Процитировано
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