Hair Cortisol in Young Children with Autism and Their Parents: Associations with Child Mental Health, Eating Behavior and Weight Status
Journal of Autism and Developmental Disorders,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 22, 2025
Abstract
Children
with
autism
and
their
parents
face
daily
challenges
that
may
be
stressful
for
both.
However,
little
is
known
about
biological
stress
(hair
cortisol
concentrations
[HCC])
in
these
families
its
connection
to
children’s
health
outcomes.
This
study
investigates
children
associations
child
mental
health,
eating
behavior
BMI.
Stress
was
measured
102
young
(101
mothers,
86
fathers)
using
HCC
self-reported
parenting
(OBVL).
Child
through
symptoms
(ADOS-2,
SRS-2)
problem
(CBCL).
(CEBQ)
BMIz
were
also
measured.
had
higher
than
peers.
not
linked
behavior,
or
BMIz.
Maternal
(self-reported
HCC)
associated
behavior.
In
fathers,
correlated
(SRS-2)
problems.
Both
parents’
specifically
emotional
undereating
overeating.
conclusion,
levels
comparison
from
the
general
population,
suggest
differences
stress-regulation
autism.
Given
findings,
monitoring
research
clinical
practice
could
improve
our
understanding
of
The
association
between
parental
behaviors,
underscores
importance
considering
family
dynamics
(preventive)
interventions
further
addresses
physical
Язык: Английский
Hair Cortisol and Psychiatric Symptomatology in Children; Outcomes of Group CBT
Comprehensive Psychoneuroendocrinology,
Год журнала:
2024,
Номер
20, С. 100263 - 100263
Опубликована: Сен. 12, 2024
Язык: Английский
Impact of Physical Activity, Sedentary Behavior, and Basal Metabolic Rate on PTSD, Depression, and Emotional Instability
Brain Sciences,
Год журнала:
2024,
Номер
14(11), С. 1071 - 1071
Опубликована: Окт. 27, 2024
Objective:
This
study
aimed
to
investigate
the
potential
associations
between
physical
activity,
sedentary
behavior,
and
basal
metabolic
rate
(BMR)
with
post-traumatic
stress
disorder
(PTSD),
major
depressive
(MDD),
emotional
instability
(EI)
using
bidirectional
Mendelian
randomization
(MR).
Additionally,
it
sought
identify
key
molecular
mechanisms
underlying
through
a
comprehensive
bioinformatic
analysis.
Methods:
MR
analyses
utilizing
genome-wide
association
(GWAS)
data
were
conducted
estimate
effects
of
BMR
on
PTSD,
MDD,
EI.
Sensitivity
performed
assess
robustness
findings.
Concurrently,
analysis
was
executed
gene
expression
datasets
(GSE53987
GSE21138)
derived
from
emotionally
unstable
patients.
encompassed
differential
differentially
expressed
genes
(DEGs),
followed
by
an
functional
enrichment
uncover
pathways
associated
Results:
The
revealed
that
increased
activity
may
have
protective
effect
against
albeit
inconsistent
MDD
Sedentary
behavior
demonstrated
minimal
or
identified
114
DEGs
EI,
YWHAB,
SRRM2,
MST1,
HDAC10,
HSPA1A
highlighted
as
significant
genes.
these
unveiled
potentially
involved
in
pathology
instability.
Conclusions:
Physical
appears
protect
whereas
its
EI
are
less
definitive.
findings
offer
deeper
understanding
pinpointing
specific
serve
therapeutic
targets.
Further
research
is
warranted
elucidate
intricate
interactions
mechanisms.
Язык: Английский