Smart SPIONs for Multimodal Cancer Theranostics: A Review DOI

Piyush Pawar,

Arati Prabhu

Molecular Pharmaceutics, Год журнала: 2025, Номер unknown

Опубликована: Апрель 14, 2025

Despite significant advancements in anticancer research, the performance statistics of current therapeutic regimens yield unsatisfactory outcomes. Issues such as high metastasis rates, drug resistance, limited efficacy, and severe side effects underscore urgent need for safer more effective strategies tumor mitigation. One promising approach lies use superparamagnetic iron oxide nanoparticles (SPIONs) hybridized cancer therapy, leveraging their unique properties functional versatility to enhance treatment efficacy safety. They can serve platforms various well diagnostic applications, enhancing imaging techniques magnetic resonance imaging. This paper presents an in-depth compilation application nanoparticulate SPIONs amalgamates multimodal therapeutics. Physical phenomena light, heat, sound, magnetism be coupled delivery systems developing targeted, precision medicine against cancer. Integration noninvasive technologies photodynamic photothermal hyperthermia, sonodynamic therapy hold great promise counteracting daunting challenges within

Язык: Английский

Smart SPIONs for Multimodal Cancer Theranostics: A Review DOI

Piyush Pawar,

Arati Prabhu

Molecular Pharmaceutics, Год журнала: 2025, Номер unknown

Опубликована: Апрель 14, 2025

Despite significant advancements in anticancer research, the performance statistics of current therapeutic regimens yield unsatisfactory outcomes. Issues such as high metastasis rates, drug resistance, limited efficacy, and severe side effects underscore urgent need for safer more effective strategies tumor mitigation. One promising approach lies use superparamagnetic iron oxide nanoparticles (SPIONs) hybridized cancer therapy, leveraging their unique properties functional versatility to enhance treatment efficacy safety. They can serve platforms various well diagnostic applications, enhancing imaging techniques magnetic resonance imaging. This paper presents an in-depth compilation application nanoparticulate SPIONs amalgamates multimodal therapeutics. Physical phenomena light, heat, sound, magnetism be coupled delivery systems developing targeted, precision medicine against cancer. Integration noninvasive technologies photodynamic photothermal hyperthermia, sonodynamic therapy hold great promise counteracting daunting challenges within

Язык: Английский

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