DUS4L suppresses invasion and metastasis in LUAD via modulation of PI3K/AKT and ERK/MAPK signaling through GRB2

International Immunopharmacology, Год журнала: 2024, Номер 142, С. 113043 - 113043

Опубликована: Авг. 30, 2024

Limited research has focused on the role of dihydrouridine synthases (DUS) family members in human tumors. Our previous findings indicated an impact synthase 4 like (DUS4L) cell proliferation and apoptosis lung adenocarcinoma (LUAD) A549 cell, yet its broader functions regulatory mechanisms LUAD remain elusive.

Язык: Английский

Histopathological analysis potential for unveiling hormone signaling in endocrine-related tumors

Endocrine Oncology, Год журнала: 2024, Номер 4(1)

Опубликована: Янв. 1, 2024

Elucidating the mechanisms of action steroid hormones will contribute to development therapeutic strategies for hormone-dependent tumors. Recent advances in genetic engineering have revealed complex and diverse hormone signaling; however, these techniques are limited

Язык: Английский