The effect of deprescribing interventions on mortality and health outcomes in older people: An updated systematic review and meta‐analysis DOI Creative Commons
Hui Wen Quek, Amy Page, Kenneth Lee

и другие.

British Journal of Clinical Pharmacology, Год журнала: 2024, Номер unknown

Опубликована: Авг. 20, 2024

Abstract Aims Previous systematic reviews suggest that deprescribing may improve survival, particularly in frail older people. Evidence is rapidly accumulating, suggesting a need for an updated review of the literature. Methods We 2016 and meta‐analysis to include studies published from inception 26 April 2024 specified databases. Studies which people had at least one medication deprescribed were included grouped by study designs targeted medications. The risk bias was assessed using Cochrane tool Newcastle‐Ottawa tool. Odds ratios (OR) or mean differences calculated as effect measures either Mantel–Haenszel generic inverse‐variance method with fixed‐ random‐effects meta‐analyses. primary outcome mortality. Secondary outcomes adverse drug withdrawal events, physical health, cognitive function, quality life on regimen. Subgroup analyses performed based age intervention types. Results A total 259 (reported 286 papers) this review. Deprescribing polypharmacy did not result significant reduction mortality both randomized (OR 0.96, 95% confidence interval [CI] 0.84–1.09) non‐randomized 0.70, CI 0.36–1.38). Further subgroup demonstrated young old (aged 65–79) 0.71, 0.51–0.99) when patient‐specific interventions applied 0.79, 0.63–0.99). Conclusions can be achieved potentially important benefits terms improved are initiated early old.

Язык: Английский

Systematic literature review of the impact of psychiatric pharmacists DOI Creative Commons
Jessica L. Ho,

Jenna Roberts,

Gregory H. Payne

и другие.

Mental Health Clinician, Год журнала: 2024, Номер 14(1), С. 33 - 67

Опубликована: Фев. 1, 2024

Pharmacists focusing on psychotropic medication management and practicing across a wide variety of healthcare settings have significantly improved patient-level outcomes. The Systematic Literature Review Committee the American Association Psychiatric was tasked with compiling comprehensive database primary literature highlighting impact psychiatric pharmacists

Язык: Английский

Процитировано

6
Withdrawal of antihypertensive drugs in older people DOI
Danijela Gnjidic, Aili Langford, Vanessa Jordan

и другие.

Cochrane library, Год журнала: 2025, Номер 2025(3)

Опубликована: Март 31, 2025

Язык: Английский

Процитировано

0
The effect of deprescribing interventions on mortality and health outcomes in older people: An updated systematic review and meta‐analysis DOI Creative Commons
Hui Wen Quek, Amy Page, Kenneth Lee

и другие.

British Journal of Clinical Pharmacology, Год журнала: 2024, Номер unknown

Опубликована: Авг. 20, 2024

Abstract Aims Previous systematic reviews suggest that deprescribing may improve survival, particularly in frail older people. Evidence is rapidly accumulating, suggesting a need for an updated review of the literature. Methods We 2016 and meta‐analysis to include studies published from inception 26 April 2024 specified databases. Studies which people had at least one medication deprescribed were included grouped by study designs targeted medications. The risk bias was assessed using Cochrane tool Newcastle‐Ottawa tool. Odds ratios (OR) or mean differences calculated as effect measures either Mantel–Haenszel generic inverse‐variance method with fixed‐ random‐effects meta‐analyses. primary outcome mortality. Secondary outcomes adverse drug withdrawal events, physical health, cognitive function, quality life on regimen. Subgroup analyses performed based age intervention types. Results A total 259 (reported 286 papers) this review. Deprescribing polypharmacy did not result significant reduction mortality both randomized (OR 0.96, 95% confidence interval [CI] 0.84–1.09) non‐randomized 0.70, CI 0.36–1.38). Further subgroup demonstrated young old (aged 65–79) 0.71, 0.51–0.99) when patient‐specific interventions applied 0.79, 0.63–0.99). Conclusions can be achieved potentially important benefits terms improved are initiated early old.

Язык: Английский

Процитировано

3