Antibiotic Consumption Patterns in Urban Coari, Amazonas: High Azithromycin Use and COVID-19-Related Prescriptions

Pharmacoepidemiology, Год журнала: 2025, Номер 4(1), С. 3 - 3

Опубликована: Янв. 4, 2025

Background/Objectivses: Antibiotic consumption patterns in remote urban areas of the Amazon region are poorly understood. This study aimed to analyze antibiotic use adult population Coari, a municipality Amazonas, Brazil. Methods: A cross-sectional was conducted between October and November 2021 area Coari. 394 adults were interviewed using structured questionnaire. Data on use, sociodemographic factors, health service access, self-reported illnesses collected. Poisson regression used estimate prevalence ratios identify factors associated with use. Results: The 14.7% (n = 58). most frequently antibiotics azithromycin (26.9%), cefalexin (20.9%), amoxicillin (19.4%), ciprofloxacin (13.9%). Up 34.5% without prescription, especially among aged 18 39 (59.1%). main problems that led self-medication COVID-19 (28.6%), urinary infection (14.3%), sore throat (37.5%), intestinal (60.0%). Factors included age (adjusted PR 3.73; CI 1.37–10.09), having family member hospitalized 2.61; 1.39–4.89), contracted 2.41; 1.40–4.15), frequency visits by community agent home 0.35 0.15–0.81). Conclusions: high broad-spectrum (Watch), particularly azithromycin, for potentially inappropriate indications highlights need improve management regions Community agents, as key professionals services community, can play role promoting rational combating antimicrobial resistance Brazilian context.

Язык: Английский

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Arsenic-Induced Modulation of Virulence and Drug Resistance in Pseudomonas aeruginosa

Journal of Hazardous Materials, Год журнала: 2025, Номер 488, С. 137352 - 137352

Опубликована: Янв. 24, 2025

Язык: Английский

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A review of the environmental spread of Salmonella enterica serovars through water in Africa

Letters in Applied Microbiology, Год журнала: 2025, Номер 78(2)

Опубликована: Янв. 23, 2025

Salmonella is an enteric pathogenic bacterium in mammals that thrives sewage, soil, and aquatic environments because of its wide ecological adaptability. The spread infection associated with a lack clean water, poor hygiene, sanitation developing countries. However, the input Salmonella-contaminated surface water groundwater environmental dissemination antimicrobial-resistant obscure outside developed This study aimed to assess literature described from groundwater, treated Africa profiled bacteria for antimicrobial resistance (AMR). We seek highlight pitfalls S. enterica identification schemes determine entry routes into comprehend patterns through ecosystem. was frequently recovered not only but also unprotected springs river Africa. insufficiency standard methods limited speciation few studies determined isolates' AMR patterns. Integrating surveillance global can assist controlling typhoid fever generally reduce burden waterborne infections

Язык: Английский

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Aquatic photochemistry for different dissociation forms of cephalosporin antibiotics: Degradation kinetics, products and photo-modified toxicity

Environmental Pollution, Год журнала: 2025, Номер 371, С. 125926 - 125926

Опубликована: Фев. 25, 2025

Язык: Английский

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A review of antibiotic resistance genes in major river basins in China: Distribution, drivers, and risk

Environmental Pollution, Год журнала: 2025, Номер unknown, С. 125920 - 125920

Опубликована: Фев. 1, 2025

Язык: Английский

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