Updates on the neurological manifestations of SARS-CoV-2 infection
Current Opinion in Infectious Diseases,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 1, 2025
Purpose
of
review
Since
its
emergence
in
2020,
the
COVID-19
pandemic
has
created
a
global
surge
survivors
experiencing
neurologic
effects
from
SARS-CoV-2
infection.
This
aims
to
provide
an
updated
synthesis
acute
and
chronic
neurological
manifestations
COVID-19,
outline
current
therapeutic
strategies
for
these
conditions.
Recent
findings
Epidemiological
studies
have
shown
that
patients
with
symptoms
during
infection
tend
poorer
hospital
functional
outcomes.
While
risk
adverse
including
cognitive
dysfunction,
headache,
autonomic
fatigue
are
thought
be
greatest
following
original
strain
alpha
variant,
they
remain
prevalent
after
subsequent
less
virulent
strains
as
well.
Some
recent
work
also
found
link
between
structural
brain
changes.
However,
ongoing
trials
show
promising
results
pharmacologic
nonpharmacologic
treatments
targeting
postacute
sequelae
COVID-19.
Summary
Lingering
still
pose
considerable
individual,
healthcare
system,
socioeconomic
repercussions.
Both
preventive
multimodal
treatment
approaches
necessary
address
Further
research
is
required
assess
lasting
impacts
on
nervous
particularly
potential
contribution
development
neurodegenerative
diseases.
Язык: Английский
All-cause healthcare resource utilization and costs among community-managed adults with long-COVID in France, 2020–2023
Journal of Medical Economics,
Год журнала:
2025,
Номер
28(1), С. 535 - 543
Опубликована: Апрель 8, 2025
The
clinical
and
economic
burden
of
long
COVID
is
poorly
understood.
We
aim
to
assess
all-cause
healthcare
resource
utilization
(HCRU)
costs
in
the
primary
care
setting
among
adults
with
France.
A
retrospective
cohort
study
using
electronic
records
(EHRs)
confirmed
and/or
probable
COVID-19
patients
from
Health
Improvement
Network
(THIN)
data
between
March
2020
December
2022
was
conducted.
Long
identified
per
World
Organization
(WHO)
definition
as
suggestive
symptoms
present
≥3
months
following
acute
SARS-CoV-2
infection.
Patients'
characteristics,
HCRU,
direct
indirect
(National
Insurance-based
prices)
were
summarized.
Costs
previous
infection
who
developed
COVID,
did
not
develop
(COVID
only),
contemporaneous
controls
without
compared
(Non-COVID).
30,122
(11.6%)
adults;
mean
(SD)
age
50
(17)
years,
63.6%
female
27.5%
had
a
Charlson
Comorbidity
Index
score
>2.
During
post-infection
follow-up
(mean
=
13
months),
97.3%
general
practitioner
consultations
(GP)
62.4%
nursing
care.
highest
during
first
post-diagnosis
year
patient
€2,443
(total
cost
€52
million),
including
for
GP
(€208)
specialist
(€170)
consultations,
outpatient
procedures
(€413),
retail
pharmacy
use
(€595),
biological
testing
(€147),
medical
device
usage
(€172).
Patients
additional
€163
€176
when
only
Non-COVID
cohorts,
respectively.
Since
THIN
database
generated
EHRs,
there
possibility
measurement/documentation
errors
missing
values
which
could
compromise
validity
accuracy
certain
results.
associated
non-negligible
French
system.
These
findings
reinforce
importance
optimizing
long-term
allocation
infected
SARS-CoV-2.
Язык: Английский
Long COVID in 2025: a clinical viewpoint
Life Sciences,
Год журнала:
2025,
Номер
unknown, С. 123633 - 123633
Опубликована: Апрель 1, 2025
Язык: Английский
Gastrointestinal manifestations of long COVID
Life Sciences,
Год журнала:
2024,
Номер
unknown, С. 123100 - 123100
Опубликована: Сен. 1, 2024
Язык: Английский
Digital Approaches in Post-COVID Healthcare: A Systematic Review of Technological Innovations in Disease Management
Biology Methods and Protocols,
Год журнала:
2024,
Номер
9(1)
Опубликована: Янв. 1, 2024
Abstract
Post-COVID
conditions
(PCC)
emerged
during
the
pandemic,
prompting
a
rise
in
use
of
Digital
Health
Technologies
(DHTs)
to
manage
lockdowns
and
hospital
overcrowding.
Real-time
tracking
information
analyses
were
crucial
strengthening
global
research
response.
This
study
aims
map
modern
digital
approaches
estimating
prevalence,
predicting,
diagnosing,
treating,
monitoring,
prognosis
PCC.
review
was
conducted
by
searching
PubMed
Scopus
databases
for
keywords
synonyms
related
DHTs,
Smart
Healthcare
Systems,
PCC
based
on
World
Organization
definition.
Articles
published
from
1
January
2020
21
May
2024
screened
eligibility
predefined
inclusion
criteria,
PRISMA
framework
used
report
findings
retained
studies.
Our
search
identified
377
studies,
but
we
23
studies
that
artificial
intelligence
(AI),
infodemiology
diagnose,
estimate
predict,
treat,
monitor
Notably,
few
interventions
infodemics
identify
clinical
presentations
disease,
while
most
utilized
Electronic
Records
AI
tools
diagnosis
prevalence.
However,
found
scarcely
monitoring
symptoms,
involving
SHS
non-existent
low-
middle-income
countries
(LMICs).
These
show
several
DHTs
healthcare,
there
is
an
urgent
need
further
complex
health
conditions,
particularly
LMICs.
Enhancing
integrating
provide
promising
avenues
managing
epidemics
complications,
such
as
Язык: Английский