Dubai Medical Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 8, 2024
Introduction:
Amyotrophic
lateral
sclerosis
(ALS),
a
neurodegenerative
disease
that
causes
muscle
weakness,
paralysis,
and
death,
develops
when
motor
neurons
begin
to
die.
There
are
few
proven
treatments
for
ALS,
because
the
is
incurable,
exact
cause
unknown,
making
it
devastating
condition.
According
recent
research,
marine
algae
may
contain
bioactive
substances
can
be
used
treat
ALS.
Methods:
The
comprehensive
review
of
publications
focused
on
compounds
extracted
from
various
species
algae,
including
their
mechanisms
action
against
oxidative
stress,
neuroinflammation,
apoptosis
in
were
reviewed
scientific
journals
(ScienceDirect,
Springer,
Taylor
&
Francis,
MDPI)
indexed
several
databases
(Scopus,
Web
Science,
PubMed,
Google
Scholar,
so
on).
Discussion:
Compounds
derived
polyunsaturated
fatty
acids,
fucoxanthin,
polysaccharides,
exhibit
potential
neuroprotective
effects
by
modulating
neuroinflammation
stress
levels.
Fucoxanthin,
fucosterol,
alginate
demonstrated
mitigating
damage
inflammation,
which
critical
factors
pathogenesis
Conclusion:
Bioactive
obtained
demonstrate
considerable
as
therapeutic
agents
owing
capacity
influence
multiple
pathways
linked
neuroinflammation.
Further
investigation
required
comprehend
medicinal
value,
well
develop
novel
alternative
Agriculture,
Год журнала:
2024,
Номер
14(5), С. 685 - 685
Опубликована: Апрель 27, 2024
This
study
aimed
to
investigate
how
diets
supplemented
with
DHA-rich
algae
affect
the
expression
of
liver
lipid
synthesis
genes
in
dairy
goat
bucks.
The
results
revealed
that
when
algae,
weight
and
serum
HDL-C
were
significantly
increased
(p
<
0.05),
as
well
LDL-C
was
decreased
0.05).
Transcriptome
sequencing
indicated
supplementation
alters
gene
expression.
differentially
expressed
predominantly
enriched
fatty
acid
metabolism
biosynthesis
unsaturated
acids.
desaturation
transcription
factors
(SCD,
FADS1,
INSIG1),
de
novo
acids
(FASN),
transport
(LDLR),
cholesterol
steroid
(HMGCR,
HMGCS1,
SQLE)
oxidation
(ALDH3B1)
In
conclusion,
this
research
provided
preliminary
evidence
dietary
supplements
altered
Saanen
Advances in medical technologies and clinical practice book series,
Год журнала:
2024,
Номер
unknown, С. 117 - 146
Опубликована: Сен. 25, 2024
Cancer
is
a
pathological
condition
characterized
by
the
uncontrolled
growth
and
dissemination
of
certain
cells
inside
body.
Currently,
cancer
poses
significant
global
challenge.
The
marine
ecosystem
bountiful
reservoir
biologically
potent
compounds
that
carry
enormous
promise
for
treatment
various
ailments,
particularly
cancer.
anticancer
properties
natural
have
been
previously
demonstrated
in
both
laboratory
animal
investigations.
field
marine-based
pharmaceuticals
has
begun
to
an
influence
on
current
pharmacology.
Various
anti-cancer
therapies
are
developed
from
components
officially
approved
clinical
usage.
This
book
chapter
specifically
examines
bioactive
obtained
habitats
properties.
It
also
explores
therapeutic
applications
these
molecules
wide
range
innovative
sources
species
purposes.
Dubai Medical Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 8, 2024
Introduction:
Amyotrophic
lateral
sclerosis
(ALS),
a
neurodegenerative
disease
that
causes
muscle
weakness,
paralysis,
and
death,
develops
when
motor
neurons
begin
to
die.
There
are
few
proven
treatments
for
ALS,
because
the
is
incurable,
exact
cause
unknown,
making
it
devastating
condition.
According
recent
research,
marine
algae
may
contain
bioactive
substances
can
be
used
treat
ALS.
Methods:
The
comprehensive
review
of
publications
focused
on
compounds
extracted
from
various
species
algae,
including
their
mechanisms
action
against
oxidative
stress,
neuroinflammation,
apoptosis
in
were
reviewed
scientific
journals
(ScienceDirect,
Springer,
Taylor
&
Francis,
MDPI)
indexed
several
databases
(Scopus,
Web
Science,
PubMed,
Google
Scholar,
so
on).
Discussion:
Compounds
derived
polyunsaturated
fatty
acids,
fucoxanthin,
polysaccharides,
exhibit
potential
neuroprotective
effects
by
modulating
neuroinflammation
stress
levels.
Fucoxanthin,
fucosterol,
alginate
demonstrated
mitigating
damage
inflammation,
which
critical
factors
pathogenesis
Conclusion:
Bioactive
obtained
demonstrate
considerable
as
therapeutic
agents
owing
capacity
influence
multiple
pathways
linked
neuroinflammation.
Further
investigation
required
comprehend
medicinal
value,
well
develop
novel
alternative
