Frontiers in Bioengineering and Biotechnology,
Год журнала:
2024,
Номер
11
Опубликована: Янв. 10, 2024
Green
synthesis
of
metal
nanoparticles
(NPs)
has
received
extensive
attention
over
other
conventional
approaches
due
to
their
non-toxic
nature
and
more
biocompatibility.
Herein
we
report
gold
silver
NPs
(AuNPs@AV
AgNPs@AV)
prepared
by
employing
a
green
approach
using
crude
extract
Aconitum
violaceum
Jacquem.
ex
Stapf.
The
synthesized
were
characterized
Scanning
Electron
Microscopy
(SEM),
Transmission
(TEM),
Energy
Dispersive
X-ray
(EDX),
Diffraction
(XRD),
UV/Visible
spectroscopy,
Fourier
Transform
Infrared
(FTIR),
Photoelectron
Spectroscopy
(XPS),
Zeta
Potential.
Morphological
analysis
showed
spherical
triangular
shapes
the
with
average
size
<100
nm.
AuNPs@AV
AgNPs@AV
exhibited
effective
antibacterial
activities,
minimum
inhibitory
concentrations
(MICs)
95
70
μg/mL
against
Lactobacillus
acidophilus
(
L.
)
90
65
Escherichia
coli
E.
),
respectively.
Strong
antioxidant
effect
reported
DPPH
radical
PTIO
within
range
IC
50
values;
161–80
μg/ml
as
compared
standard
(23–11
μg/mL)
Moreover,
efficient
photocatalytic
activity
degraded
89.88%
93.7%
methylene
blue
(MB)
dye
under
UV
light,
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 3187 - 3215
Опубликована: Апрель 1, 2024
Abstract:
Green
synthesis
of
silver
(Ag)
and
gold
(Au)
nanoparticles
(NPs)
has
acquired
huge
popularity
owing
to
their
potential
applications
in
various
fields.
A
large
number
research
articles
exist
the
literature
describing
green
Ag
Au
NPs
for
biomedical
applications.
However,
these
findings
are
scattered,
making
it
time-consuming
researchers
locate
promising
advancements
unexplored
Unlike
other
review
articles,
this
systematic
study
not
only
highlights
recent
but
also
explores
The
article
discusses
approaches
highlighting
emerging
developments
novel
strategies.
Then,
reviews
important
synthesized
by
critically
evaluating
expected
advantages.
To
expose
future
direction
field,
describes
NPs.
Finally,
discuss
challenges
limitations
This
will
serve
as
a
valuable
reference
researchers,
working
on
Keywords:
nanoparticles,
environmental-friendly,
applications,
potentials
Journal of Functional Biomaterials,
Год журнала:
2024,
Номер
15(8), С. 207 - 207
Опубликована: Июль 25, 2024
Photothermal
therapy
(PTT)
can
overcome
cancer
treatment
resistance
by
enhancing
the
cell
membrane
permeability,
facilitating
drug
accumulation,
and
promoting
release
within
tumor
tissue.
Iron
oxide
nanoparticles
(IONPs)
have
emerged
as
effective
agents
for
PTT
due
to
their
unique
properties
biocompatibility.
Approved
of
anemia,
MRI
contrast
agents,
magnetic
hyperthermia
mediators,
IONPs
also
offer
excellent
light-to-heat
conversion
be
manipulated
using
external
fields
targeted
accumulation
in
specific
Optimizing
parameters
such
laser
wavelength,
power
density,
shape,
size,
iron
oxidation
state,
functionalization,
concentration
is
crucial
IONPs'
effectiveness.
In
addition
PTT,
enhance
other
modalities.
They
improve
oxygenation,
efficacy
radiotherapy
photodynamic
therapy.
trigger
ferroptosis,
a
programmed
death
pathway
mediated
iron-dependent
lipid
peroxidation.
Their
magneto-mechanical
effect
allows
them
exert
mechanical
force
on
cells
destroy
tumors,
minimizing
damage
healthy
This
review
outlines
strategies
management
photothermal
performance
efficiency
with
nanoparticles,
well
synergies
therapies.
Heliyon,
Год журнала:
2023,
Номер
9(6), С. e16919 - e16919
Опубликована: Июнь 1, 2023
Currently,
the
incidence
of
metabolic
disorders
is
increasing,
setting
a
challenge
to
global
health.
With
major
advancement
in
diagnostic
tools
and
clinical
procedures,
much
has
been
known
etiology
their
corresponding
pathophysiologies.
In
addition,
use
vitro
vivo
experimental
models
prior
studies
promoted
numerous
biomedical
breakthroughs,
including
discovery
development
drug
candidates
treat
disorders.
Indeed,
chemicals
isolated
from
natural
products
have
extensively
studied
as
prospective
manage
diabetes,
obesity,
heart-related
diseases,
cancer,
partly
due
antioxidant
anti-inflammatory
properties.
Continuous
efforts
made
parallel
improve
bioactivity
bioavailability
using
selected
delivery
approaches.
Here,
we
provide
insights
on
recent
progress
role
inflammatory-mediated
responses
initiation
disorders,
with
particular
reference
diabetes
mellitus,
cancer.
discussed
management
cancers
lists
potential
biological
targets
for
high
throughput
screening
development.
Lastly,
findings
observed
preclinical
identifying
suitable
approaches
phytochemical
systems
that
are
be
used
treatment
Journal of Multidisciplinary Applied Natural Science,
Год журнала:
2023,
Номер
4(1), С. 108 - 119
Опубликована: Окт. 7, 2023
A
green
synthesis
method
utilizing
Musa
paradisiaca
peel
extract
as
a
reducing
and
stabilizing
agent
was
employed
to
produce
iron
oxide
nanoparticles.
The
synthesized
nanoparticles
were
extensively
characterized
using
FTIR,
XRD,
DLS,
SEM,
EDX,
TEM
techniques.
FTIR
analysis
confirmed
the
presence
of
metal
functional
groups
derived
from
extract.
XRD
results
indicated
magnetite
(Fe3O4)
and/or
maghemite
(γ-Fe2O3)
phases,
signifying
high
degree
crystallinity.
DLS
provided
valuable
insights
into
size
distribution
polydispersity
nanoparticles,
revealing
an
average
particle
diameter
43.35
nm
index
0.612.
SEM
examination
uncovered
aggregated
formations,
where
irregularly
shaped
exhibited
either
close
packing
or
loose
association,
resulting
in
formation
larger
aggregates.
These
environmentally
friendly
could
potentially
hold
great
promise
for
variety
biological
applications,
including
potential
drug
delivery
antimicrobial
applications.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 18, 2025
This
study
presents
a
novel
adsorbent
for
the
removal
of
Gefitinib
from
water
using
1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic
acid
modified
SiO2@SPION
nanoparticles
(as
SPION@CPFO-PAC).
Several
investigations
were
conducted
to
examine
chemical
characteristics,
morphological
aspects,
thermal
stability,
and
magnetic
behavior
produced
nano
adsorbent.
Based
on
analysis
findings,
exhibited
superparamagnetic
properties.
The
findings
TEM
SEM
pictures
indicate
that
synthesis
technique
resulted
in
creation
uniform
nanoparticles,
mostly
spherical
shape,
with
an
average
size
20–25
nm.
These
exhibit
well-defined
structure
possess
excellent
stability.
Under
optimal
conditions
(100
ng/mL-10
mL
Gefitinib,
dosage
=
0.02
g,
t
30
min),
drug
elimination
percentage
reached
92.02%.
results
these
adsorption
studies
described
Freundlich
isotherm,
pseudo-second-order
model
well
kinetics
adsorption.
thermodynamic
investigation
indicates
process
is
spontaneous
exothermic,
as
shown
by
ΔH
ΔG
values
at
various
temperatures.
examined
capacity
retrieve
nanoadsorbent
found
it
could
be
efficiently
separated
reused
four
consecutive
cycles
without
significant
decrease
effectiveness.
