A comprehensive review on advances in nanoparticle-mediated cancer therapeutics: Current research and future perspectives
V.C. Deivayanai,
P. Thamarai,
S. Karishma
и другие.
Cancer Pathogenesis and Therapy,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 1, 2024
Язык: Английский
Drug Delivery Systems Based on Metal–Organic Frameworks for Tumor Immunotherapy
Pharmaceutics,
Год журнала:
2025,
Номер
17(2), С. 225 - 225
Опубликована: Фев. 10, 2025
Metal–organic
frameworks
(MOFs)
are
a
class
of
inorganic-organic
hybrid
nanoparticles
formed
by
the
coordination
metal
ions/clusters
and
organic
ligands.
Due
to
their
high
porosities,
large
surface
areas,
adjustable
structures,
responsiveness
light/sound,
etc.,
MOFs
have
shown
great
clinical
potential
in
field
tumor
therapy.
Tumor
immunotherapy
exerts
antitumor
effects
through
reshaping
immune
microenvironment,
showing
significant
preclinical
advantages.
Based
on
mechanisms
immunity
activation,
agents
can
be
divided
into
chemotherapeutic
agents,
immunomodulators,
enzymes,
vaccines
oligonucleotide
drugs,
etc.
Herein,
we
review
MOFs-based
drug
delivery
systems
for
immunotherapy.
The
classification
MOFs,
followed
activation
mechanisms,
first
introduced.
Drug
based
with
different
also
summarized,
especially
synergetic
triggered
loadings.
Furthermore,
merits
drawbacks
strategies
promote
applications
discussed.
Язык: Английский
PEGylated Elesclomol@Cu(Ⅱ)-based Metal‒organic Framework with Effective Nanozyme Performance and Cuproptosis Induction Efficacy for Enhanced PD-L1-based Immunotherapy
Materials Today Bio,
Год журнала:
2024,
Номер
29, С. 101317 - 101317
Опубликована: Окт. 30, 2024
Язык: Английский
A simple two-dimensional metal–organic framework–based phototherapy nanoplatform with a triple-synergistic mechanism for enhanced wound infection treatment
Journal of Colloid and Interface Science,
Год журнала:
2025,
Номер
694, С. 137656 - 137656
Опубликована: Апрель 19, 2025
Язык: Английский
Hyaluronic acid-modified doxorubicin-covalent organic framework nanoparticles triggered pyroptosis in combinations with immune checkpoint blockade for the treatment of breast cancer
Shengsheng Zhao,
Binglong Bai,
Bingzi Zhu
и другие.
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 143265 - 143265
Опубликована: Апрель 1, 2025
Язык: Английский