
Research Square (Research Square), Год журнала: 2023, Номер unknown
Опубликована: Ноя. 25, 2023
Язык: Английский
Research Square (Research Square), Год журнала: 2023, Номер unknown
Опубликована: Ноя. 25, 2023
Язык: Английский
Psychiatry Research, Год журнала: 2024, Номер 335, С. 115886 - 115886
Опубликована: Март 28, 2024
Язык: Английский
Процитировано
25European Journal of Trauma & Dissociation, Год журнала: 2024, Номер 8(1), С. 100378 - 100378
Опубликована: Янв. 7, 2024
Язык: Английский
Процитировано
16Journal of Clinical Medicine, Год журнала: 2023, Номер 12(9), С. 3289 - 3289
Опубликована: Май 5, 2023
The vast majority of injured patients suffer from pain. Systematic assessment pain on admission to the emergency department (ED) is a cornerstone translating best treatment strategies for patient care into practice. Pain must be measured with severity scales that are validated in clinical practice, including specific populations (such as children and older adults). Although primary ED trauma focuses resuscitation, diagnosis treatment, management remains critical element professionals not prepared provide effective early therapy. To date, most EDs have protocols take account patient's hemodynamic status condition give preference non-pharmacological approaches where possible. When selecting medications, focus those least disruptive status. relief may still necessary hemodynamically unstable patients, but caution should exercised, especially when using opioids, absorption impaired or shock exacerbated. analgesic dose ketamine certainly an attractive option. Fentanyl clearly superior other opioids initial resuscitation it has minimal effects does cause central nervous system depression. Inhaled analgesia techniques ultrasound-guided nerve blocks also increasingly solutions. A multimodal approach, which involves use two more drugs different mechanisms action, plays important role All policies promote adoption procedures all patients.
Язык: Английский
Процитировано
27Trauma Surgery & Acute Care Open, Год журнала: 2025, Номер 10(1), С. e001336 - e001336
Опубликована: Янв. 1, 2025
Background Up to 20–40% of survivors any traumatic injury develop post-traumatic stress disorder (PTSD) or depression after injury. Firearm may be at even higher risk for adverse outcomes. We aimed characterize PTSD and risk, pain symptoms, ongoing functional limitations in firearm early hospital discharge. Methods seen the Trauma Quality Life (TQOL) outpatient follow-up clinic 1–2 weeks discharge were invited participate a survey assessing both mental physical health The included Brief Pain Inventory (BPI), Injured Survivor Screen (ITSS), Beck Depression (BDI), Checklist DSM-5 (PCL-5), 12-item Short Form Survey Physical Health component (SF-12) Results 306 patients TQOL Clinic, 175 responded survey. mean age was 32 years (SD=12), 81% male, 79% black. On ITSS, 69% 48% screened positive depression, respectively. Patients reported mild symptoms with an average BDI score 14.3 (SD=11.8) elevated PCL-5 43.8 (SD=12.8). severe BPI scores more likely screen PTSD. Respondents scored >2 SD below US national on SF-12 quality life (M=28.7). 12% across all four domains pain, PTSD, function. Conclusion Early discharge, over two-thirds development nearly half function significantly decreased. centers need prioritize early, multidisciplinary care treat prevent poor chronic survivors. Level evidence III.
Язык: Английский
Процитировано
1World Journal of Psychiatry, Год журнала: 2023, Номер 13(6), С. 331 - 339
Опубликована: Июнь 19, 2023
There are various types of traumatic stimuli, such as catastrophic events like wars, natural calamities earthquakes, and personal trauma from physical psychological neglect or abuse sexual abuse. Traumatic can be divided into type I II trauma, their impacts on individuals depend not only the severity duration traumas but also individuals' self-evaluation events. Individual stress reactions to include posttraumatic disorder (PTSD), complex PTSD trauma-related depression. Trauma-related depression is a reactive with unclear pathology, occurring due in childhood has gained increasing attention, because it persisted for long time does respond conventional antidepressants shows good partial response psychotherapy, which similar pattern observed PTSD. Because associated high risk suicide chronic propensity relapse, necessary explore its pathogenesis therapeutic strategy.
Язык: Английский
Процитировано
19Frontiers in Psychology, Год журнала: 2024, Номер 15
Опубликована: Июль 17, 2024
The long-term impact of COVID-19 on the mental health and well-being college students, specifically trends over time after full removal restrictions, has not been well-studied.
Язык: Английский
Процитировано
5Neuroscience Bulletin, Год журнала: 2025, Номер unknown
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0Frontiers in Aging, Год журнала: 2025, Номер 6
Опубликована: Фев. 5, 2025
Introduction Observational studies have reported that patients with Alzheimer’s disease (AD) a greater burden of comorbidities typically associated stress-related psychiatric disorders. However, the contribution hereditary factors to this comorbidity remains unclear. We evaluated phenotypic associations using observational data from UK Biobank. Method Our study focused on investigating shared risk variants and genetic etiology underlying AD three disorders: post-traumatic stress disorder, anxiety major depressive disorder. By leveraging summary statistics genome-wide association studies, we investigated global correlations linkage disequilibrium score regression, covariance analysis, high-definition likelihood. Genome-wide cross-trait analysis based subsets cross-phenotype were performed discover significant between Results A positive correlation was observed disorder regression (rg = 0.231; P 0.018), 0.138; < 0.001), likelihood 0.188; 0.001). Association revealed thirteen in six genes disorder; seven four 23 Functional annotation gene-set enrichment indicated 12 for all disorders enriched spleen, pancreas, whole blood. Conclusion These results advance our knowledge origins pave way advancements diagnosis, management, prevention AD.
Язык: Английский
Процитировано
0Neuroscience Bulletin, Год журнала: 2025, Номер unknown
Опубликована: Фев. 9, 2025
Язык: Английский
Процитировано
0European Journal of Trauma and Emergency Surgery, Год журнала: 2025, Номер 51(1)
Опубликована: Фев. 13, 2025
Язык: Английский
Процитировано
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