Anti-Aging Eastern Europe, Год журнала: 2024, Номер 3(4), С. 207 - 211
Опубликована: Дек. 28, 2024
Frailty, a multidimensional syndrome marked by diminished physiological reserve and increased vulnerability, hasemerged as critical concern in systemic sclerosis (SSc). Both age-related inflamm-aging disease-related chronicinflammation contribute to the higher prevalence of frailty SSc patients compared their age-matched counterparts. Frailty is strongly associated with adverse outcomes, including skin involvement, disability, physical inactivity, hospitalization rates, malnutrition, severe gastrointestinal symptoms, interstitial lung disease, elevated mortality. This hypothesis posits an overlooked factor progression severity SSc. Early identification at its pre-frailty stage essential. Implementing targeted preventative strategies could mitigate impact, significantly enhancing long-term disease management clinical outcomes for
Язык: Английский