Study on the Role and Pathological and Immune Responses of Silver Nanoparticles Against Two Aeromonas salmonicida subsp. salmonicida Strains at Different Virulence Levels in Rainbow Trout (Oncorhynchus mykiss) DOI Creative Commons
Yu Guo,

Chaoli Zheng,

Yingfei Wang

и другие.

Fishes, Год журнала: 2025, Номер 10(1), С. 29 - 29

Опубликована: Янв. 13, 2025

Aeromonas species are among the main pathogens causing rainbow trout infections. Silver nanoparticles (AgNPs) have a broad spectrum of antimicrobial properties and usually produced by various green-synthesis methods. However, application commercialized AgNPs has not fully been clarified. Thus, objective this study was to evaluate antibacterial activities (range sizes 10–12 nm) on two contrasting A. salmonicida strains (I-1 I-4), isolated from trout; mechanism, histopathological alterations expression immune-related genes were investigated. In vitro, minimal inhibitory concentration (MIC) 10 µg/mL for I-1, lowered 9.5 I-4, respectively. shown disrupt both cell wall membrane I-1 resulting in lysis degradation. vivo, challenged immersed or intraperitoneally injected infection, AgNP-treated groups, showed delayed deaths lower mortalities compared control without any clinical signs pathological changes. Especially virulent enhanced expressions TNF-α, IL-1β, IL-10 IL-11 significantly reduced group, indicating lesser inflammation due AgNPs. This would lay theoretical foundation wide silver fish diseases.

Язык: Английский

Genomic insights into fish pathogenic bacteria: A systems biology perspective for sustainable aquaculture DOI
Raju Sasikumar, S. Saranya,

L. Lourdu Lincy

и другие.

Fish & Shellfish Immunology, Год журнала: 2024, Номер unknown, С. 109978 - 109978

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

7
Synthesis of Undoped and Mixed Binary Transition Metals (Ni-Co)-Doped Cupric Oxide Nanostructures: Structural Characteristics, Optical Behavior, and Biological Activity DOI

M. Karthikeyan,

J. Gajendiran,

S. Gnanam

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1321, С. 139895 - 139895

Опубликована: Сен. 3, 2024

Язык: Английский

Процитировано

5
Study on the Role and Pathological and Immune Responses of Silver Nanoparticles Against Two Aeromonas salmonicida subsp. salmonicida Strains at Different Virulence Levels in Rainbow Trout (Oncorhynchus mykiss) DOI Creative Commons
Yu Guo,

Chaoli Zheng,

Yingfei Wang

и другие.

Fishes, Год журнала: 2025, Номер 10(1), С. 29 - 29

Опубликована: Янв. 13, 2025

Aeromonas species are among the main pathogens causing rainbow trout infections. Silver nanoparticles (AgNPs) have a broad spectrum of antimicrobial properties and usually produced by various green-synthesis methods. However, application commercialized AgNPs has not fully been clarified. Thus, objective this study was to evaluate antibacterial activities (range sizes 10–12 nm) on two contrasting A. salmonicida strains (I-1 I-4), isolated from trout; mechanism, histopathological alterations expression immune-related genes were investigated. In vitro, minimal inhibitory concentration (MIC) 10 µg/mL for I-1, lowered 9.5 I-4, respectively. shown disrupt both cell wall membrane I-1 resulting in lysis degradation. vivo, challenged immersed or intraperitoneally injected infection, AgNP-treated groups, showed delayed deaths lower mortalities compared control without any clinical signs pathological changes. Especially virulent enhanced expressions TNF-α, IL-1β, IL-10 IL-11 significantly reduced group, indicating lesser inflammation due AgNPs. This would lay theoretical foundation wide silver fish diseases.

Язык: Английский

Процитировано

0