Synthesis of Eco‐Friendly Nanostructured Lipid Carriers Decorated With Magnetic Nanoparticle Encapsulated Sesbania sesban Extract Against Vector Borne Culex pipiens (Diptera: Culicidae) and Musca domestica (Diptera: Muscidae) as Green Insecticides
Entomological Research,
Год журнала:
2025,
Номер
55(3)
Опубликована: Март 1, 2025
ABSTRACT
Mosquito‐borne
diseases
remain
a
significant
health
concern
amidst
current
microbial
outbreaks.
Phytochemicals
offer
environmentally
safe,
biodegradable,
and
targeted
pest
management.
Nanostructure
lipid
carriers
(NLCs),
second
generation
of
solid
nanoparticles,
are
gaining
attention
as
potential
diagnostic
therapeutic
tools.
Sesbania
leaves,
rich
in
fatty
acids,
phenolics,
terpenes,
were
analyzed
using
gas
chromatography–mass
spectrometry.
Magnetic
nanoparticles
(Se‐NLC‐MNPs)
modified
the
surface
extract,
encapsulated
NLC.
The
resulting
129.2
218.5
nm
size,
with
zeta
potentials
−6.20
43.9
mV,
respectively.
Transmission
electron
microscopy
showed
spherical
oval
shapes.
XRD
patterns
confirmed
successful
decoration
NLC
magnetic
nanoparticles.
extract
(Se)
its
nanoparticle
conjugates
tested
for
larvicidal
efficacy
against
Culex
pipiens
Musca
domestica
larvae,
at
doses
ranging
from
50
to
1500
ppm
0.1
5
mg/mL.
Se‐NLC‐MNPs
higher
larval
mortality
rates
compared
their
Se
formulation
extracts,
achieving
100%
third‐instar
larvae.
methanol
contained
more
other
organic
compounds
than
aqueous
making
it
harmful
insect
In
terms
relative
toxicity,
effective
Se‐NLC.
An
vitro
cytotoxicity
assay
WI38
cell
line
indicated
assay,
suggesting
these
develop
into
high‐performance,
acceptable
therapeutics
mosquito‐borne
diseases.
Язык: Английский
Study of the effect of dryness and storage on Ceratonia siliqua L. stem extracts and evaluation of their insecticidal activity
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Апрель 1, 2025
Abstract
Vector-borne
diseases
continue
to
transmit
many
dangerous
pathogens
humans.
After
decades
of
continuous
use
insecticides,
types
vectors
have
shown
the
ability
build
resistance
them.
This
has
necessitated
development
more
efficient
and
environmentally
friendly
alternatives
in
form
bioinsecticides.
Plants
contain
a
wide
range
phytochemicals
with
specific
targeting,
rapid
biodegradability,
environmental
sustainability
variety
medicinal
properties,
making
them
valuable
source
biologicals.
Moreover,
this
led
highly
effective
new
drugs.
study
aimed
identify
active
ingredients
Ceratonia
siliqua
L.,
gathered
from
two
consecutive
fruiting
seasons
which
were
then
divided
into
C.
fresh
(CSF),
dry
(CSd),
old
(stored)
stem
(CSO)
extracts
.
Metabolomics
profiling
was
performed
using
UPLC/MS
multivariate
data
analysis.
The
resulted
tentative
identification
54
secondary
metabolites.
These
compounds
included
flavonoids,
phenolic
acids,
withanolides,
terpenoids,
phenylpropanoids,
etc.
CSd
showed
highest
number
identified
components
followed
by
CSO
CSF.
%
nearly
equal
negative
ion
mode
for
three
while
positive
it
order
CSF
>
CSO.
several
exposure
periods,
plant
methanol
research
significant
insecticidal
activity
against
mosquito
larvae,
Cx.
pipiens
,
housefly
larvae
M.
domestica
(CSd)
demonstrated
(100
MO%)
(LC
50
=
0.09
0.07
mg/ml)
following
24-
48-hour
post-treatments
at
1.0
mg/ml.
(CSF)
most
on
2.32
1.80
mg/ml),
24
48
h
post-treatment
25
mg/ml
concentration.
Both
killing
house
fly
extract.
Therefore,
may
serve
as
an
bio-agent
vector-borne
infection
control.
Язык: Английский