Assay and Drug Development Technologies, Год журнала: 2025, Номер unknown

Опубликована: Март 13, 2025

RNA interference through small interfering (siRNA) has shown great promise as a potential cancer treatment strategy in recent years. However, the delivery of siRNA to target cells efficiently remains significant challenge. This review aims highlight advances nanotechnology-enabled for treatment, bridging gap between bench research and clinical application. A comprehensive literature search was conducted identify studies focused on utilization nanotechnology treatment. Key databases, including PubMed, Scopus, Web Science, were used, relevant articles screened. Several nanotechnology-based platforms have emerged years, providing enhanced selectivity, improved stability, controlled release profiles. The primary types nanocarriers discussed include lipid-based nanoparticles, inorganic polymeric exosomes. Nanotechnology-based systems represent promising avenue Although progress been made preclinical studies, translating these findings applications poses several challenges, scale-up production, safety, targeted delivery. Nevertheless, developments this field hold revolutionizing therapy, hope more effective personalized options future.

Язык: Английский