Cell Response to Oxidative Stress in Antarctic Filamentous Fungi DOI Creative Commons

Radoslav Abrashev,

Jeny Miteva‐Staleva, Yana Gocheva

и другие.

Applied Sciences, Год журнала: 2025, Номер 15(9), С. 5149 - 5149

Опубликована: Май 6, 2025

Antarctica, with its harsh environmental conditions, is home to a wide variety of microorganisms, including filamentous fungi. The survival Antarctic mycoflora has led increasing interest in their adaptation. Extreme low temperatures, water availability, frequent freeze–thaw cycles, strong winds, ultraviolet radiation, etc., are all prerequisites for accelerated production reactive oxygen species (ROS) and the occurrence oxidative stress (OS). fungi have effective mechanisms cope damaging effects ROS. While distribution, morphology, physiology, biotechnological potential these well documented, role adaptation poorly understood. This been one main research topics our team long time, number papers on results published. review summarizes existing literature induction psychrophilic, psychrotolerant, mesophilic by extreme conditions. most recent relevant studies reporting relationship between cold OS biomarkers ROS key intracellular biomolecules presented. contribution both enzymatic non-enzymatic antioxidant defenses fungal cell response discussed.

Язык: Английский

In Vivo Pathogenicity Characterization of Viable Opportunistic Fungi Aspergillus thermomutatus and Rhodotorula mucilaginosa Recovered from Maritime Antarctic Permafrost DOI Creative Commons
Eldon Carlos Queres Gomes, Vívian N. Gonçalves, Marliete Carvalho da Costa

и другие.

Environment & Health, Год журнала: 2025, Номер 3(4), С. 436 - 442

Опубликована: Фев. 3, 2025

In this study, we evaluated the pathogenic potential of fungi Aspergillus thermomutatus and Rhodotorula mucilaginosa obtained from maritime Antarctic permafrost using in vivo experiments on immunocompromised BALB/c mice. Despite low mortality observed, immunosuppressed animals infected with A. R. exhibited fluctuations body mass induced changes neuropsychiatric state Fungi were recovered lungs, spleen, blood, brain mice at densities similar to but slightly lower than inoculum up 5 days post-inoculation. infection an inflammatory process lungs target organs mucilaginosa, a notable fungal load was detected brains animals. These results suggest that viable isolates such as originating permafrost, which is exposed increasing melt caused by rising temperatures region, may present significant potential. This highlights climate change Antarctica facilitate release dispersal other microorganisms capable infecting humans

Язык: Английский

Процитировано

0
Cell Response to Oxidative Stress in Antarctic Filamentous Fungi DOI Creative Commons

Radoslav Abrashev,

Jeny Miteva‐Staleva, Yana Gocheva

и другие.

Applied Sciences, Год журнала: 2025, Номер 15(9), С. 5149 - 5149

Опубликована: Май 6, 2025

Antarctica, with its harsh environmental conditions, is home to a wide variety of microorganisms, including filamentous fungi. The survival Antarctic mycoflora has led increasing interest in their adaptation. Extreme low temperatures, water availability, frequent freeze–thaw cycles, strong winds, ultraviolet radiation, etc., are all prerequisites for accelerated production reactive oxygen species (ROS) and the occurrence oxidative stress (OS). fungi have effective mechanisms cope damaging effects ROS. While distribution, morphology, physiology, biotechnological potential these well documented, role adaptation poorly understood. This been one main research topics our team long time, number papers on results published. review summarizes existing literature induction psychrophilic, psychrotolerant, mesophilic by extreme conditions. most recent relevant studies reporting relationship between cold OS biomarkers ROS key intracellular biomolecules presented. contribution both enzymatic non-enzymatic antioxidant defenses fungal cell response discussed.

Язык: Английский

Процитировано

0