Journal of The Electrochemical Society,
Год журнала:
2024,
Номер
171(9), С. 097508 - 097508
Опубликована: Сен. 2, 2024
Biosensors
are
inevitable
tools
for
biomedical
applications,
including
disease
diagnosis,
monitoring,
and
drug
management.
Integrated
with
nanotechnology,
these
biosensors
have
improved
patient
outcomes
by
providing
rapid
strategic
prognosis,
remote
access,
decreasing
the
burden
of
present-day
healthcare
facilities.
Due
to
enhanced
surface-to-volume
ratio
tunable
physicochemical
properties
nanomaterials,
nanotechnology-based
emerged
as
transformative
in
sector,
offering
unparalleled
sensitivity
specificity
detecting
analyzing
biological
molecules
targeted
diagnosis.
This
review
explores
advancements
biosensor
technology,
emphasizing
integration
various
metal
nanoparticles,
carbon
quantum
dots,
enhance
device
performance
terms
sensitivity,
selectivity,
stability.
We
discuss
operational
principles
different
types-
such
electrochemical,
optical,
solid-state,
DNA-based
sensors
their
applications
healthcare,
from
early
detection
personalized
treatment
Moreover,
delves
into
challenges,
alternate
solutions,
future
prospects
development,
highlighting
role
artificial
intelligence,
bioinformatics,
5
G
communication
creating
next-generation
smart
applications.
ACS Chemical Neuroscience,
Год журнала:
2025,
Номер
16(5), С. 895 - 907
Опубликована: Фев. 20, 2025
Ischemic
stroke
remains
a
leading
cause
of
morbidity
and
mortality
worldwide,
early
diagnosis
is
critical
for
improving
clinical
outcomes.
This
paper
presents
an
optical
design
framework
combining
speckle
contrast
spectroscopy
(SCOS)
with
multiwavelength
reflectance
to
monitor
subtle
changes
in
cerebral
blood
flow
during
ischemic
events.
The
research
aims
enable
precise
tissue
interrogation
using
high-resolution,
low-scatter
imaging.
Key
the
system's
accuracy
1.55
μm
small
beam
waist,
grating
density
1300
grooves/mm,
15.53
depth
focus.
calculated
effective
focal
length
8333.33
enhances
resolution
4.07
μm,
detection
minor
properties.
We
investigate
sensitivity
various
near-infrared
wavelengths
(660,
785,
800,
976
nm)
ischemic-induced
changes,
particular
emphasis
on
nm
wavelength,
which
demonstrates
superior
penetration
increased
variations
perfusion
ischemia.
Optical
markers
such
as
spot-size
widening,
spatial
intensity
shifts,
central
decrease
are
identified
reliable
indicators
Our
findings
suggest
that
analysis,
particularly
range,
provides
practical,
noninvasive
approach
continuously
monitoring
strokes.
technique
indicates
potential
real-time
perfusion,
allows
continuous,
management
strokes,
patient
outcomes
decision-making.
ACS Omega,
Год журнала:
2024,
Номер
9(50), С. 48918 - 48987
Опубликована: Дек. 6, 2024
Biosensors
are
transforming
healthcare
by
delivering
swift,
precise,
and
economical
diagnostic
solutions.
These
analytical
instruments
combine
biological
indicators
with
physical
transducers
to
identify
quantify
biomarkers,
thereby
improving
illness
detection,
management,
patient
surveillance.
widely
utilized
in
for
the
diagnosis
of
chronic
infectious
diseases,
tailored
treatment,
real-time
health
monitoring.
This
thorough
overview
examines
several
categories
biosensors
their
uses
detection
numerous
including
glucose,
proteins,
nucleic
acids,
infections.
commonly
classified
based
on
type
transducer
employed
or
specific
biorecognition
element
utilized.
review
introduces
a
novel
classification
substrate
morphology,
offering
comprehensive
perspective
biosensor
categorization.
Considerable
emphasis
is
placed
advancement
point-of-care
biosensors,
facilitating
decentralized
diagnostics
alleviating
strain
centralized
systems.
Recent
advancements
nanotechnology
have
significantly
improved
sensitivity,
selectivity,
downsizing
rendering
them
more
efficient
accessible.
The
study
problems
such
as
stability,
reproducibility,
regulatory
approval
that
must
be
addressed
enable
widespread
implementation
clinical
environments.
amalgamation
wearable
devices
smartphones,
emphasizing
prospects
ongoing
surveillance
individualized
medical
care.
viewpoint
clarifies
distinct
types
particular
roles,
together
recent
developments
"smart
biosensor"
sector,
facilitated
artificial
intelligence
Internet
Medical
Things
(IoMT).
approach
seeks
deliver
evaluation
present
condition
technology
healthcare,
developments,
prospective
paths,
significance
influencing
future
Journal of The Electrochemical Society,
Год журнала:
2024,
Номер
171(9), С. 097508 - 097508
Опубликована: Сен. 2, 2024
Biosensors
are
inevitable
tools
for
biomedical
applications,
including
disease
diagnosis,
monitoring,
and
drug
management.
Integrated
with
nanotechnology,
these
biosensors
have
improved
patient
outcomes
by
providing
rapid
strategic
prognosis,
remote
access,
decreasing
the
burden
of
present-day
healthcare
facilities.
Due
to
enhanced
surface-to-volume
ratio
tunable
physicochemical
properties
nanomaterials,
nanotechnology-based
emerged
as
transformative
in
sector,
offering
unparalleled
sensitivity
specificity
detecting
analyzing
biological
molecules
targeted
diagnosis.
This
review
explores
advancements
biosensor
technology,
emphasizing
integration
various
metal
nanoparticles,
carbon
quantum
dots,
enhance
device
performance
terms
sensitivity,
selectivity,
stability.
We
discuss
operational
principles
different
types-
such
electrochemical,
optical,
solid-state,
DNA-based
sensors
their
applications
healthcare,
from
early
detection
personalized
treatment
Moreover,
delves
into
challenges,
alternate
solutions,
future
prospects
development,
highlighting
role
artificial
intelligence,
bioinformatics,
5
G
communication
creating
next-generation
smart
applications.