Promoted Non-enzymatic Glucose Sensor Based on Synergistic Effect of Hydrothermal Synthesized Ni(OH)2-Graphene Nanocomposite DOI
Yuqing Cai, Qingyan Cui, Huanrong Zhang

и другие.

Chemical Research in Chinese Universities, Год журнала: 2024, Номер unknown

Опубликована: Сен. 14, 2024

Язык: Английский

Multifunctional Hydrogel Microneedles (HMNs) in Drug Delivery and Diagnostics DOI Creative Commons
Hossein Omidian, Sumana Dey Chowdhury

Gels, Год журнала: 2025, Номер 11(3), С. 206 - 206

Опубликована: Март 15, 2025

Hydrogel microneedles (HMNs) have emerged as a transformative platform for minimally invasive drug delivery and biosensing, offering enhanced bioavailability, controlled release, real-time biomarker detection. By leveraging swelling hydrogels, nanomaterial integration, stimuli-responsive properties, HMNs provide precision medicine capabilities across diverse therapeutic diagnostic applications. However, challenges remain in mechanical stability, hydrogel-based MNs must balance flexibility with sufficient strength skin penetration. Drug retention release require optimization to prevent premature diffusion ensure sustained effects. Additionally, biosensing accuracy is influenced by variability interstitial fluid extraction signal transduction. Clinical translation hindered regulatory hurdles, scalability concerns, the need extensive safety validation human trials. This review critically examines key materials, fabrication techniques, functional testing frameworks of while addressing these limitations. Furthermore, we explore future research directions smart wearable MNs, AI-assisted hybrid drug–device platforms optimize transdermal medicine. Overcoming barriers will drive clinical adoption HMNs, paving way next-generation patient-centered therapeutics diagnostics.

Язык: Английский

Процитировано

2
Innovative Nanozyme-Based Detection Methods for Biomarkers in Interstitial Fluid DOI

Jiuhong Zhao,

Junjie Tian, Xiaoyu Zhang

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118248 - 118248

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

1
Engineering sampling microneedles for biomolecules sensing DOI
Yun Cheng, Xi Luan,

Jiawu Weng

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 156130 - 156130

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

4
Interfacing hydrogel microneedle patch for diagnosis DOI

Mengyao Miao,

Qiaoli Wu,

Xingwu Zhou

и другие.

Surfaces and Interfaces, Год журнала: 2024, Номер unknown, С. 105474 - 105474

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

4
3D-printed microneedles for sensing applications: emerging topics and future trends DOI Creative Commons
Kelcilene B. R. Teodoro, Tamires S. Pereira, Ana Laura M.M. Alves

и другие.

Advanced Sensor and Energy Materials, Год журнала: 2025, Номер unknown, С. 100139 - 100139

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Microneedle-Based Delivery of Metal Oxide Nanoparticles DOI
Jaison Jeevanandam, Tracy Ann Bruce‐Tagoe, Michael K. Danquah

и другие.

Series in bioengineering, Год журнала: 2025, Номер unknown, С. 299 - 315

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Facet Engineering of Cu2O for Efficient Electrochemical Glucose Sensing DOI
Chenhuinan Wei, Yang Zhang, Zhuo Wang

и другие.

Analytica Chimica Acta, Год журнала: 2024, Номер 1336, С. 343525 - 343525

Опубликована: Дек. 6, 2024

Язык: Английский

Процитировано

1
Promoted Non-enzymatic Glucose Sensor Based on Synergistic Effect of Hydrothermal Synthesized Ni(OH)2-Graphene Nanocomposite DOI
Yuqing Cai, Qingyan Cui, Huanrong Zhang

и другие.

Chemical Research in Chinese Universities, Год журнала: 2024, Номер unknown

Опубликована: Сен. 14, 2024

Язык: Английский

Процитировано

0