Talanta, Год журнала: 2025, Номер unknown, С. 127944 - 127944

Опубликована: Март 1, 2025

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants known for their toxicity, mobility, bioaccumulation. Efficient sample preparation analysis of these compounds critical monitoring. In this study, a novel analytical methodology is presented, integrating dynamic headspace extraction (DHS) thermal desorption (TD) with one-dimensional (1D) two-dimensional (2D) gas chromatography-time-of-flight mass spectrometry (GC-TOFMS) the quantification target volatile semi-volatile PFAS. Such an approach also enables non-targeted screening other classes in aqueous samples. The method was optimized validated nine (semi-)volatile PFAS, including fluorotelomer alcohols (FTOHs), acrylate (FTAc), alkyl sulfonamides (FOSA, FOSE). Three types adsorbent materials were evaluated during enrichment step, among which Tenax TA demonstrated superior recovery reproducibility. Extraction volumes 1 L, 2 5 L tested, providing most consistent recoveries achieved detection limits as low 2.17 ng L-1, indicating high sensitivity. case study involving water from industrial site, enhanced separation capabilities GC×GC-TOFMS enabled identification 115 additional environmentally relevant compounds, halogen-containing monoaromatics, polycyclic aromatic hydrocarbons. This integrated DHS-TD-GC×GC-TOFMS provides robust suitable solution targeted PFAS monitoring, combining sensitivity selectivity simultaneous - particularly advantageous feature monitoring chemicals real

Язык: Английский