Membranes,
Год журнала:
2023,
Номер
13(5), С. 480 - 480
Опубликована: Апрель 29, 2023
Separation
is
one
of
the
most
energy-intensive
processes
in
chemical
industry,
and
membrane-based
separation
technology
contributes
significantly
to
energy
conservation
emission
reduction.
Additionally,
metal-organic
framework
(MOF)
materials
have
been
widely
investigated
found
enormous
potential
membrane
due
their
uniform
pore
size
high
designability.
Notably,
pure
MOF
films
mixed
matrix
membranes
(MMMs)
are
core
"next
generation"
materials.
However,
there
some
tough
issues
with
MOF-based
that
affect
performance.
For
membranes,
problems
such
as
flexibility,
defects,
grain
orientation
need
be
addressed.
Meanwhile,
still
exist
bottlenecks
for
MMMs
aggregation,
plasticization
aging
polymer
matrix,
poor
interface
compatibility,
etc.
Herein,
corresponding
methods
introduced
solve
these
problems,
including
inhibiting
regulating
synthesis
conditions,
enhancing
interaction
between
substrate.
A
series
high-quality
obtained
based
on
techniques.
Overall,
revealed
desired
performance
both
gas
(e.g.,
CO
Langmuir,
Год журнала:
2024,
Номер
40(43), С. 22477 - 22503
Опубликована: Окт. 17, 2024
The
porous
materials
known
as
metal-organic
frameworks
(MOFs)
stand
out
for
their
enormous
surface
area,
adaptable
pore
size
and
shape,
structural
variety.
These
characteristics
make
them
well-suited
various
applications,
especially
in
healthcare.
This
review
thoroughly
summarizes
recent
studies
on
the
use
of
MOFs
drug
delivery,
biosensing,
therapeutics.
may
encapsulate
medications,
target
certain
cells
or
tissues,
regulate
release
over
time.
Additionally,
have
potential
to
be
used
biosensing
allowing
selective
detection
chemical
biological
substances.
MOFs'
optical
electrical
modified
biosensors
that
track
physiological
data.
show
targeted
delivery
regulated
therapeutic
substances
cancer
treatment.
In
addition,
they
work
potent
antibacterial
agents,
providing
a
less
dangerous
option
than
traditional
antibiotics
increase
antibiotic
resistance.
For
practical
further
research
is
required
well
more
consideration
problems
with
toxicity
biocompatibility.
addition
addressing
difficulties
promising
possibilities
this
study
intends
provide
insights
into
healthcare
Despite
several
essential
reviews
it
was
necessary
look
most
therapy
combined
concept.
Chemosensors,
Год журнала:
2024,
Номер
12(7), С. 135 - 135
Опубликована: Июль 9, 2024
Electrochemical
biosensors
are
critical
in
advancing
biomedical
and
pharmaceutical
therapies
because
of
their
adaptability
cost-effectiveness.
Voltammetric
amperometric
sensors
particular
interest.
These
typically
consist
a
specialized
tip
or
biorecognition
element
transducer
that
converts
biological
data
into
readable
signals.
Efficient
biosensor
materials
essential
for
addressing
health
emergencies,
with
coordination
polymers
(CPs)
metal–organic
frameworks
(MOFs)
showing
promise.
Functionalization
strategies
necessary
to
enhance
the
usability
pristine
MOFs,
owing
issues
such
as
low
conductivity.
The
integration
conductive
MOFs
has
resulted
development
highly
efficient
biosensors.
Both
enzymatic
nonenzymatic
used
analyte
detection;
approaches
gaining
popularity
durability
accuracy.
CPs
have
been
applied
sensitive
electrochemical
detect
fatal
brain
tumors
glioblastomas
(GBM).
demonstrate
enhanced
selectivity
sensitivity,
highlighting
potential
technology
both
vivo
vitro
applications.
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 6, 2025
Abstract
Neurodegenerative
diseases,
particularly
Alzheimer's
disease
and
Parkinson's
disease,
present
formidable
challenges
in
modern
medicine
due
to
their
complex
pathologies
the
absence
of
curative
treatments.
Despite
advances
symptomatic
management,
early
diagnosis
remains
essential
for
mitigating
progression
improving
patient
outcomes.
Traditional
diagnostic
methods,
such
as
MRI,
PET,
cerebrospinal
fluid
biomarker
analysis,
are
often
inadequate
detection
these
diseases.
Emerging
porous
materials,
including
metal–organic
frameworks
(MOFs),
covalent–organic
(COFs),
MXene,
zeolites,
silicon,
offer
promising
new
approaches
neurodegenerative
These
characterized
by
highly
tunable
physicochemical
properties,
have
potential
capture
concentrate
disease‐specific
biomarkers
amyloid‐beta
(Aβ),
tau
protein,
alpha‐synuclein
(α‐Syn).
The
integration
materials
into
advanced
biosensors
real‐time
holds
promise
revolutionizing
neurodiagnostic,
enabling
non‐invasive,
sensitive,
specific
platforms.
Furthermore,
incorporation
artificial
intelligence
(AI)
machine
learning
(ML)
techniques
analysis
sensor
data
enhances
accuracy
allows
more
efficient
interpretation
profiles.
AI
ML
can
optimize
feature
selection,
improve
pattern
recognition,
facilitate
prediction
progression,
making
them
indispensable
tools
personalized
medicine.
This
review
explores
diagnostics,
emphasizing
design,
functionality,
synergistic
role
advancing
clinical
applications.
Scientific Reports,
Год журнала:
2022,
Номер
12(1)
Опубликована: Июль 15, 2022
The
aim
of
this
work
was
to
provide
a
novel
approach
designing
and
synthesizing
nanocomposite
with
significant
biocompatibility,
biodegradability,
stability
in
biological
microenvironments.
Hence,
the
porous
ultra-low-density
materials,
metal-organic
frameworks
(MOFs),
have
been
considered
MIL-125(Ti)
has
chosen
due
its
distinctive
characteristics
such
as
great
biocompatibility
good
biodegradability
immobilized
on
surface
reduced
graphene
oxide
(rGO).
Based
results,
presence
transition
metal
complexes
next
drug
not
only
can
reinforce
structure
by
preparing
π-π
interaction
between
ligands
but
also
enhance
efficiency
preventing
spontaneous
release.
effect
utilizing
complex
beside
(Doxorubicin
(DOX))
loading,
release,
antibacterial
activity
prepared
nanocomposites
P.
aeruginosa
S.
aureus
model
bacterium
investigated
results
revealed
that
theory
leads
increasing
about
200%
activity.
In
addition,
uptake,
release
drug,
relative
cell
viabilities
(in
vitro
vivo)
nanomaterials
biomaterials
discussed.
collected
data,
median
size
156.2
nm,
their
PBS
DMEM
+
10%
FBS
screened
after
2.880
min,
nanocomposite's
reached
242.3
516
nm
respectively.
MTT
demonstrated
immobilizing
PdL
DOX
an
increase
more
than
15%
viability.
It
is
noticeable
AST:ALT
result
under
1.5.
Materials Today Bio,
Год журнала:
2023,
Номер
21, С. 100717 - 100717
Опубликована: Июнь 27, 2023
Bone
defects
induced
by
bone
trauma,
tumors
and
osteoarthritis
greatly
affect
the
life
quality
health
of
patients.
The
biomaterials
with
numerous
advantages
are
becoming
most
preferred
options
for
repairing
treating
orthopedic
diseases.
However,
their
effects
remains
unsatisfactory,
especially
in
suffering
from
tumor,
inflammation,
and/or
bacterial
infection.
There
several
strategies
to
functionalize
biomaterials,
but
a
more
general
efficient
method
is
essential
accomplishing
functionalization
biomaterials.
Possessing
high
specific
surface,
porosity,
controlled
degradability
variable
composition,
metal-organic
frameworks
(MOFs)
materials
inherently
advantageous
functionalizing
tremendous
improvements
having
been
achieved.
This
review
summarizes
recent
progresses
MOFs
functionalized
promoting
repair
therapeutic
effects.
In
specific,
utilizing
various
properties
diverse
materials,
integrated
achieve
enhanced
regeneration,
antibacterial,
anti-inflammatory
anti-tumor
functions.
Finally,
summary
prospects
on
development
MOFs-functionalized
were
discussed.
