Piezoelectric Biomaterials for Use in Bone Tissue Engineering—A Narrative Review DOI Open Access
Sandeep Choudhury, Debaprasad Das, Sandipan Roy

и другие.

Journal of Biomedical Materials Research Part B Applied Biomaterials, Год журнала: 2025, Номер 113(4)

Опубликована: Март 17, 2025

ABSTRACT To examine natural bone's bioelectrical traits, notably its piezoelectricity, and to look into how these characteristics influence bone growth repair. In the context of exploring potential piezoelectric biomaterials, such as biopolymers bio‐ceramics, towards orthopedic regeneration applications, research seeks evaluate significance piezoelectricity‐driven osteogenesis. The paper reviews recent on electrical dielectric properties, surface polarization/electrical stimulation effects interacting with cell activity effectiveness biomaterials support tissues' regenerative process. study includes a number materials, collagen, polyvinylidene fluoride (PVDF) barium titanate. applications organic polymers, polymers are particularly highlighted. Piezoelectric being shown in studies enhance cellular metabolism vitro well promote tissues vivo, especially when paired electric field or interface polarization. bio‐ceramics like magnesium silicate titanate, collagen PVDF, have possibilities for applications. However, there several challenges regarding manufacturing specific compositions having desired properties. This review highlighted special emphasis bioceramics. Therefore, types materials huge because they can mimic properties allow better advances tissue engineering medicine. date, little is known about their mechanism action, modifications needed improve efficacy clinical uptake.

Язык: Английский

On the Structural and Biological Effects of Hydroxyapatite and Gold Nano-Scale Particles in Poly(Vinylidene Fluoride) Smart Scaffolds for Bone and Neural Tissue Engineering DOI Creative Commons
Angelika Zaszczyńska, Marzena Zychowicz,

Dorota Kołbuk

и другие.

Molecules, Год журнала: 2025, Номер 30(5), С. 1041 - 1041

Опубликована: Фев. 25, 2025

Piezoelectric materials, due to their ability generate an electric charge in response mechanical deformation, are becoming increasingly attractive the engineering of bone and neural tissues. This manuscript reports effects addition nanohydroxyapatite (nHA), introduction gold nanoparticles (AuNPs) via sonochemical coating, collector rotation speed on formation electroactive phases biological properties electrospun nanofiber scaffolds consisting poly(vinylidene fluoride) (PVDF). FTIR, WAXS, DSC, SEM results indicate that nHA increases content fiber alignment. The rotational not only alignment but also PVDF PVDF/nHA fibers. Increased orientation each additives resulted increased SFE water uptake. In vitro tests conducted MG-63 hiPSC-NSC cells showed adhesion cell proliferation. PVDF-based composites with AuNPs promising candidates for development advanced tissue applications, combining electrical functionality activity support regeneration.

Язык: Английский

Процитировано

0
Piezoelectric Biomaterials for Use in Bone Tissue Engineering—A Narrative Review DOI Open Access
Sandeep Choudhury, Debaprasad Das, Sandipan Roy

и другие.

Journal of Biomedical Materials Research Part B Applied Biomaterials, Год журнала: 2025, Номер 113(4)

Опубликована: Март 17, 2025

ABSTRACT To examine natural bone's bioelectrical traits, notably its piezoelectricity, and to look into how these characteristics influence bone growth repair. In the context of exploring potential piezoelectric biomaterials, such as biopolymers bio‐ceramics, towards orthopedic regeneration applications, research seeks evaluate significance piezoelectricity‐driven osteogenesis. The paper reviews recent on electrical dielectric properties, surface polarization/electrical stimulation effects interacting with cell activity effectiveness biomaterials support tissues' regenerative process. study includes a number materials, collagen, polyvinylidene fluoride (PVDF) barium titanate. applications organic polymers, polymers are particularly highlighted. Piezoelectric being shown in studies enhance cellular metabolism vitro well promote tissues vivo, especially when paired electric field or interface polarization. bio‐ceramics like magnesium silicate titanate, collagen PVDF, have possibilities for applications. However, there several challenges regarding manufacturing specific compositions having desired properties. This review highlighted special emphasis bioceramics. Therefore, types materials huge because they can mimic properties allow better advances tissue engineering medicine. date, little is known about their mechanism action, modifications needed improve efficacy clinical uptake.

Язык: Английский

Процитировано

0