Quantum Chemical (QC) Calculations and Linear Solvation Energy Relationships (LSER): Hydrogen-Bonding Calculations with New QC-LSER Molecular Descriptors DOI Creative Commons
Costas Panayiotou

Liquids, Год журнала: 2024, Номер 4(4), С. 663 - 688

Опубликована: Окт. 4, 2024

A new method, based on quantum chemical calculations, is proposed for the thermodynamically consistent reformulation of QSPR-type Linear Free-Energy Relationship (LFER) models. This permits extraction valuable information intermolecular interactions and its transfer in other LFER-type models, acidity/basicity scales, or even equation-of-state New molecular descriptors electrostatic are derived from distribution surface charges obtained COSMO-type calculations. The widely used very successful Abraham’s Solvation Energy (LSER) model selected as reference LSER calculations solute–solvent systems well solute self-solvation. Hydrogen-bonding free energies, enthalpies, entropies now a variety common solutes. capacity method to address role conformational changes solvation quantities discussed. perspectives with implementation also

Язык: Английский

Prediction of hydrogen-bonding interaction energies with new COSMO-based molecular descriptors DOI Creative Commons
Ioannis Zuburtikudis, William E. Acree, Costas Panayiotou

и другие.

Journal of Molecular Liquids, Год журнала: 2025, Номер unknown, С. 126907 - 126907

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

1

Radiation-Induced n-methylacetamide and β-Alanine radicals in aqueous solutions at different pH Levels: EPR spectroscopy and First-Principles calculations DOI
M. Janbazi

Journal of Molecular Liquids, Год журнала: 2025, Номер unknown, С. 127035 - 127035

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Unraveling the effect of choline-based choline based ionic liquids on the physicochemical properties and taste behavior of D( +)-glucose in aqueous solutions DOI Creative Commons

Sara Dorosti,

Hemayat Shekaari, Mohammad Bagheri

и другие.

BMC Chemistry, Год журнала: 2025, Номер 19(1)

Опубликована: Фев. 22, 2025

Язык: Английский

Процитировано

0

Vaporization enthalpy prediction of ionic liquids based on back-propagation artificial neural network DOI Creative Commons

Changzheng Ji,

Zhaochong Shi,

Yufeng Zheng

и другие.

Green Chemical Engineering, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Prediction of Hydrogen-Bonding Interaction Free Energies with Two New Molecular Descriptors DOI Creative Commons
William E. Acree, Costas Panayiotou

Liquids, Год журнала: 2025, Номер 5(2), С. 12 - 12

Опубликована: Апрель 17, 2025

This work is a continuation of our recent on the prediction hydrogen-bonding (HB) interaction enthalpies. In present work, simple method proposed for HB free energies. Quantum chemical (QC) calculations are combined with Linear Solvation Energy Relationship (LSER) approach determination novel QC-LSER molecular descriptors and development method. Each hydrogen-bonded molecule characterized by an acidity or proton donor capacity, αG, and/or basicity acceptor βG. These suffice energy when interacting molecules possess one acidic basic site. this case two molecules, 1 2, their overall cαG1βG2+βG1αG2, where c universal constant equal to (ln10)RT = 5.71 kJ/mol at 25 °C. holds true over full composition range, that is, regardless which solute solvent. complex multi-sited possessing more than distant site type sites, sets αG βG needed, as in any solvent same solute. Descriptors reported number common but they may be obtained other interest from its surface charge distribution already available easily via relatively cheap DFT/basis-set QC calculations. The new predictive scheme validated against corresponding estimations widely used Abraham’s LSER model. developments previous useful solvation studies biochemical systems and, particularly, equation-of-state thermodynamics. strengths limitations critically discussed.

Язык: Английский

Процитировано

0

A novel quantitative structure–property relationship model for predicting the maximum volumetric heating capacity and the corresponding working temperature of heat pump refrigerants DOI
Na Deng, Yuhang Wu, Baolian Niu

и другие.

Chemical Engineering Science, Год журнала: 2025, Номер unknown, С. 121703 - 121703

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Quantum Chemical (QC) Calculations and Linear Solvation Energy Relationships (LSER)-Hydrogen-Bonding Calculations with New QC-LSER Molecular Descriptors DOI Open Access
Costas Panayiotou

Опубликована: Июль 15, 2024

A new method, based on quantum chemical calculations, is proposed for the thermodynamically consistent reformulation of QSPR-type Linear Free-Energy Relationship (LFER) models. This permits extraction valuable information intermolecular interactions and its transfer in other LFER-type models, acidity / basicity scales or even equation-of-state New molecular descriptors electrostatic are derived from distribution surface charges obtained COSMO-type calculations. The widely used very successful Abraham’s Solvation Energy (LSER) model selected as reference LSER calculations solute – solvent systems well self-solvation. Hydrogen-bonding free energies, enthalpies entropies now a variety common solutes. capacity method to address role conformational changes solvation quantities discussed. perspectives with implementation also

Язык: Английский

Процитировано

2

Effect of Intramolecular Hydrogen Bond Formation on the Abraham Model Solute Descriptors for Oxybenzone DOI Creative Commons

Jocelyn Chen,

Audrey Chen,

Yixuan Yang

и другие.

Liquids, Год журнала: 2024, Номер 4(3), С. 647 - 662

Опубликована: Сен. 16, 2024

Solute descriptors derived from experimental solubility data for oxybenzone dissolved in 21 different organic solvents indicate that the hydrogen atom on hydroxyl functional group forms an intramolecular bond with lone electron pair oxygen of neighboring >C=O group. Group contribution methods developed estimating Abraham model solute molecule’s Canonical SMILES code significantly over-estimate model’s acidity descriptor oxybenzone. An informed user-modified is proposed to identify which atoms are involved H-bond formation. The identified atom(s) can be used define a new functional/fragment and numerical value.

Язык: Английский

Процитировано

2

Standard partial molar volumes of single aqueous ions composing ionic liquids measurement and evaluation of temperature dependent values. Parsing and LSER correlation with molecular descriptors based on DFT/COSMO approach DOI
Markéta Havlová, Vladimı́r Dohnal

Journal of Molecular Liquids, Год журнала: 2024, Номер 410, С. 125480 - 125480

Опубликована: Июль 14, 2024

Язык: Английский

Процитировано

1

Quantum Chemical (QC) Calculations and Linear Solvation Energy Relationships (LSER): Hydrogen-Bonding Calculations with New QC-LSER Molecular Descriptors DOI Creative Commons
Costas Panayiotou

Liquids, Год журнала: 2024, Номер 4(4), С. 663 - 688

Опубликована: Окт. 4, 2024

A new method, based on quantum chemical calculations, is proposed for the thermodynamically consistent reformulation of QSPR-type Linear Free-Energy Relationship (LFER) models. This permits extraction valuable information intermolecular interactions and its transfer in other LFER-type models, acidity/basicity scales, or even equation-of-state New molecular descriptors electrostatic are derived from distribution surface charges obtained COSMO-type calculations. The widely used very successful Abraham’s Solvation Energy (LSER) model selected as reference LSER calculations solute–solvent systems well solute self-solvation. Hydrogen-bonding free energies, enthalpies, entropies now a variety common solutes. capacity method to address role conformational changes solvation quantities discussed. perspectives with implementation also

Язык: Английский

Процитировано

1