Heat shock proteins in hypothermia: a review DOI Creative Commons

Shuang-Feng Song,

Guo–Cheng Wu, Yi Li

и другие.

Frontiers in Molecular Biosciences, Год журнала: 2025, Номер 12

Опубликована: Май 9, 2025

Hypothermia is a serious condition marked by significant decrease in core body temperature, posing considerable risks to biological systems. In response thermal stress, cells activate protective mechanisms, often synthesizing heat shock proteins (HSPs). These highly conserved are crucial cellular stress responses, primarily functioning as chaperones. HSPs facilitate correct protein folding and prevent misfolding aggregation, thereby protecting integrity during adverse conditions. This paper explains how alleviate responses related low focusing on energy metabolism, apoptosis, membrane fluidity stability, signaling pathways. By enhancing repair help maintain balance further harm the organism. Ultimately, review emphasizes complex relationship between hypothermia, highlighting their potential therapeutic targets for resistance harmful effects of extreme cold exposure. A deeper understanding these mechanisms could lead strategies that improve survival rates hypothermic patients. It may also reveal ways modulate HSPs’ activity enhanced protection.

Язык: Английский

Cotton under heat stress: a comprehensive review of molecular breeding, genomics, and multi-omics strategies DOI Creative Commons

Tahira Luqman,

Manzoor Hussain,

Syed Riaz Ahmed

и другие.

Frontiers in Genetics, Год журнала: 2025, Номер 16

Опубликована: Март 18, 2025

Cotton is a vital fiber crop for the global textile industry, but rising temperatures due to climate change threaten its growth, quality and yields. Heat stress disrupts key physiological biochemical processes, affecting carbohydrate metabolism, hormone signaling, calcium gene regulation expression. This review article explores cotton's defense mechanism against heat stress, including epigenetic regulations transgenic approaches, with focus on genome editing tools. Given limitations of traditional breeding, advanced omics technologies such as GWAS, transcriptomics, proteomics, ionomics, metabolomics, phenomics CRISPR-Cas9 offer promising solutions developing heat-resistant cotton varieties. highlights need innovative strategies ensure sustainable production under change.

Язык: Английский

Процитировано

2

Interaction and regulation of the mitochondrial proteome – in health and disease DOI Creative Commons
Johan Palmfeldt

Expert Review of Proteomics, Год журнала: 2025, Номер 22(1), С. 19 - 33

Опубликована: Янв. 2, 2025

Introduction Mitochondria contain multiple pathways including energy metabolism and several signaling synthetic pathways. Mitochondrial proteomics is highly valuable for studying diseases inherited metabolic disorders, complex common disorders like neurodegeneration, diabetes cancer, since they all to some degree have mitochondrial underpinnings.

Язык: Английский

Процитировано

0

The heat shock matters with specific attention to the expression of Hsp60 under thermal stress in fish: A critical review DOI

Md. Toasin Hossain Aunkor,

MMH Khan, Muhammad Anamul Kabir

и другие.

Ecological Genetics and Genomics, Год журнала: 2025, Номер unknown, С. 100337 - 100337

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Heat shock proteins in hypothermia: a review DOI Creative Commons

Shuang-Feng Song,

Guo–Cheng Wu, Yi Li

и другие.

Frontiers in Molecular Biosciences, Год журнала: 2025, Номер 12

Опубликована: Май 9, 2025

Hypothermia is a serious condition marked by significant decrease in core body temperature, posing considerable risks to biological systems. In response thermal stress, cells activate protective mechanisms, often synthesizing heat shock proteins (HSPs). These highly conserved are crucial cellular stress responses, primarily functioning as chaperones. HSPs facilitate correct protein folding and prevent misfolding aggregation, thereby protecting integrity during adverse conditions. This paper explains how alleviate responses related low focusing on energy metabolism, apoptosis, membrane fluidity stability, signaling pathways. By enhancing repair help maintain balance further harm the organism. Ultimately, review emphasizes complex relationship between hypothermia, highlighting their potential therapeutic targets for resistance harmful effects of extreme cold exposure. A deeper understanding these mechanisms could lead strategies that improve survival rates hypothermic patients. It may also reveal ways modulate HSPs’ activity enhanced protection.

Язык: Английский

Процитировано

0