Microwave-assisted synthesis of 2,5-dioxo-pyrano[3,2-c]quinoline-3-carboxylates and their investigation as antiproliferative agents targeting EGFR and/or BRAFV600E DOI
Ashraf A. Aly,

Hisham A. Abd El-Naby,

Essam Kh. Ahmed

и другие.

Chemical Papers, Год журнала: 2024, Номер 78(12), С. 7187 - 7199

Опубликована: Июль 29, 2024

Язык: Английский

Isolation, vibrational analysis, quantum chemical studies, nature of bonding, and molecular docking studies of triterpenoid isolates from Ganoderma lucidum as potent typhoid fever agent DOI
Emmanuel Orok Duke, Daniel Oche, Ini Ubi Bassey

и другие.

Journal of the Indian Chemical Society, Год журнала: 2023, Номер 100(8), С. 101065 - 101065

Опубликована: Июль 15, 2023

Язык: Английский

Процитировано

6
An efficient, catalyst-free and aqueous ethanol-mediated synthesis of 5-((2-aminothiazol-5-yl)(phenyl)methyl)-6-hydroxypyrimidine-2,4(1H,3H)-dione derivatives and their antioxidant activity DOI Creative Commons
Paras J. Patel, Subham G. Patel, Dipti B. Upadhyay

и другие.

RSC Advances, Год журнала: 2023, Номер 13(35), С. 24466 - 24473

Опубликована: Янв. 1, 2023

In this study, we effectively developed a catalyst-free multicomponent synthesis of 5-((2-aminothiazol-5-yl)(phenyl)methyl)-6-hydroxypyrimidine-2,4(1H,3H)-dione derivatives employing 2-aminothiazole, N',N'-dimethyl barbituric acid/barbituric acid and different aldehydes at 80 °C in an aqueous ethanol medium (1 : 1) using group-assisted purification (GAP) chemistry. The essential characteristics methodology include superior green credential parameters, metal-free synthesis, faster reaction times, greater product yields, simple without column chromatography higher yields. All the synthesized compounds were analyzed against HepG2 cell line. Compounds 4j 4k shows good anti-proliferative effects on cells. Furthermore, ABTS DPPH scavenging assays used to determine antioxidant activity all (4a-r). both radical assays, 4e, 4i, 4j, 4o 4r exhibit excellent potency compared standard ascorbic acid.

Язык: Английский

Процитировано

6
Novel MCRs of Isatins: Green Synthesis and Theoretical Study of Novel Thiazinoazepines DOI
Fahimeh Alirezapour, Fatemeh Sheikholeslami‐Farahani, Majid Moradian

и другие.

Polycyclic aromatic compounds, Год журнала: 2024, Номер unknown, С. 1 - 22

Опубликована: Окт. 2, 2024

Язык: Английский

Процитировано

2
One-pot domino synthesis of 1H-isochromene and pyran carbonitrile from pyrazole aldehyde derivatives as potential anti-diabetic and antioxidant targets DOI
Periyasamy Monisha, Singamoorthy Amalraj,

Peramaiyan Gangapriya

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1311, С. 138308 - 138308

Опубликована: Апрель 10, 2024

Язык: Английский

Процитировано

1
Microwave-assisted synthesis of 2,5-dioxo-pyrano[3,2-c]quinoline-3-carboxylates and their investigation as antiproliferative agents targeting EGFR and/or BRAFV600E DOI
Ashraf A. Aly,

Hisham A. Abd El-Naby,

Essam Kh. Ahmed

и другие.

Chemical Papers, Год журнала: 2024, Номер 78(12), С. 7187 - 7199

Опубликована: Июль 29, 2024

Язык: Английский

Процитировано

1