A convenient method for synthesis of Morita-Baylis-Hillman (MBH) 1,3-diene adducts and their in silico physicochemical, pharmacokinetics, and molecular docking evaluation studies
Phosphorus, sulfur, and silicon and the related elements,
Год журнала:
2025,
Номер
unknown, С. 1 - 16
Опубликована: Март 7, 2025
Язык: Английский
An efficient one-pot synthesis of benzofurans from functionalized tetrahydronaphtalenes
Tetrahedron,
Год журнала:
2024,
Номер
162, С. 134074 - 134074
Опубликована: Май 29, 2024
Язык: Английский
Al(OiPr)3 as an Effective Catalyst for the Enhancement of Meerwein−Ponndorf−Verley (MPV) Reductions of Morita-Baylis-Hillman (MBH) cyclic alcohols
Journal of Molecular Structure,
Год журнала:
2024,
Номер
1315, С. 138950 - 138950
Опубликована: Июнь 12, 2024
Язык: Английский
Regioselective Oxidation of Tetrahydronaphthalenes to α-Tetralone Derivatives Using DDQ as Oxidizing Agent: Synthesis and Evaluation of Antibacterial and Antifungal Activities
ACS Omega,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 11, 2024
An
easy
and
efficient
approach
for
the
synthesis
of
highly
regioselective
functionalized
dihydronaphthalen-1(2
Язык: Английский
Multigram synthesis of 2-vinylpyridine using bio-renewable 2-methyl tetrahydrofuran solvent
Phosphorus, sulfur, and silicon and the related elements,
Год журнала:
2024,
Номер
unknown, С. 1 - 4
Опубликована: Окт. 25, 2024
The
present
work
reports
the
synthesis
of
2-vinylpyridine
in
multigram
synthetic
approach
as
it
has
tremendous
application
pharmaceutical
science
well
material
and
industries.
This
method
emphasizes
usage
commercially
available
inexpensive
raw
materials
bio
renewable
solvents.
Nontoxic
TCCA
was
used
green
chlorinating
reagent
its
corresponding
bi-product
obtained
course
reaction
is
biodegradable
nature.
entire
three
step
procedure
does
not
require
any
chromatographic
techniques
product
95%
yield
with
>
98%
purity.
Язык: Английский
Novel nucleophilic addition SN2'–SN2' pathway: utilizing phosphonium salts as electrophilic agents for synthesizing new phosphine oxides of Morita–Baylis–Hillman (MBH) adducts
Comptes Rendus Chimie,
Год журнала:
2024,
Номер
27(G1), С. 269 - 279
Опубликована: Дек. 23, 2024
An
efficient
and
practical
approach
has
been
developed
for
synthesizing
phosphonates
phosphine
oxides
from
Morita–Baylis–Hillman
(MBH)
adducts
through
the
alkylation
of
trialkylphosphites
ethoxydiphenylphosphine
using
phosphonium
salts
derived
MBH
as
powerful
alkylating
agents.The
proceeds
via
a
Michaelis–Arbuzov
mechanism.
This
regiospecific
reaction
combining
SN2'
+
=
SN2
pathway
was
conducted
under
refluxing
in
CHCl3,
resulting
isolation
products
good
yields.
Une
approche
efficace
et
pratique
été
développée
pour
synthétiser
des
oxydes
de
à
partir
d'adduits
(MBH),
par
d'éthoxydiphénylphosphine
en
utilisant
sels
dérivés
comme
puissants
agents
alkylants.L'alkylation
se
déroule
le
mécanisme
Michaelis–Arbuzov.
Cette
réaction
régiospécifique
combinant
les
voies
réalisée
dans
conditions
reflux
ce
qui
permis
d'isoler
produits
avec
bons
rendements.