Exploring structure, molecular interactions, optical and thermal properties of Bis(2-Aminopyrimidinium) selenate monohydrate: A combined experimental and theoretical study
V. Vijayalakshmi,
N. Sivakumar,
V. Ali Alsulmi
и другие.
Optical Materials,
Год журнала:
2024,
Номер
152, С. 115539 - 115539
Опубликована: Май 21, 2024
Язык: Английский
Current strategies in design and synthesis of antifungals hybrid and chimeric diazine derivatives
Bioorganic & Medicinal Chemistry,
Год журнала:
2025,
Номер
119, С. 118069 - 118069
Опубликована: Янв. 13, 2025
Язык: Английский
Pyrimidines: A New Versatile Molecule in the Drug Development Field, Scope, and Future Aspects
Pharmaceuticals,
Год журнала:
2024,
Номер
17(10), С. 1258 - 1258
Опубликована: Сен. 24, 2024
Pyrimidine
is
a
moiety
that
occurs
in
living
organisms
and
has
variety
of
significant
biological
properties
pharmacology.
Due
to
the
easy
handling
synthesis,
easily
available
precursor,
less
duration
for
reaction,
not
many
technical
skills
are
needed.
All
these
factors
attract
chemists
focus
more
on
pyrimidines.
Apart
from
synthesis
applications
pyrimidines,
medicinal
have
gathered
explore
pyrimidine
scaffolds
due
their
interesting
targeting
various
binding
sites.
This
review
delves
into
diverse
activities
compounds
derived
during
year
2024.
We
attempted
growing
significance
derivatives
provide
new
path
designing
potent
molecules.
Язык: Английский
Recent advancements of pyrimidine chemistry thriving deeper into drug discovery
Synthetic Communications,
Год журнала:
2025,
Номер
unknown, С. 1 - 29
Опубликована: Апрель 3, 2025
Язык: Английский
Evaluation of anticancer potential of diorganotin(IV) complexes derived from 4-nitro-3-methylbenzhydrazide: Synthesis, spectral and single crystal analysis
Journal of Molecular Structure,
Год журнала:
2025,
Номер
unknown, С. 142361 - 142361
Опубликована: Апрель 1, 2025
Язык: Английский
The futuristic applications of transition metal dichalcogenides for cancer therapy
Luminescence,
Год журнала:
2024,
Номер
39(5)
Опубликована: Май 1, 2024
Abstract
The
second‐most
common
cause
of
death
resulting
from
genetic
mutations
in
DNA
sequences
is
cancer.
difficulty
the
field
anticancer
research
application
traditional
methods,
which
also
affects
normal
cells.
Mutations,
replication
alterations,
and
chromosomal
abnormalities
have
a
direct
impact
on
effectiveness
drugs
at
different
stages.
Presently,
therapeutic
techniques
utilize
nanotechnology,
transition
metal
dichalcogenides
(TMDCs),
robotics.
TMDCs
are
being
increasingly
employed
tumor
therapy
biosensing
applications
due
to
their
biocompatibility,
adjustable
bandgap,
versatile
functionality,
exceptional
photoelectric
properties,
wide
range
applications.
This
study
reports
advancement
nanoplatforms
based
that
specifically
engineered
for
responsive
intelligent
cancer
therapy.
article
offers
thorough
examination
current
challenges,
future
possibilities
theranostic
using
TMDCs,
recent
progress
employing
Currently,
there
significant
interest
two‐dimensional
(2D)
nanomaterials
as
ultrathin
unique
physicochemical
properties.
These
materials
attracted
attention
various
fields,
including
biomedicine.
Due
inherent
ability
absorb
near‐infrared
light
exceptionally
large
surface
area,
efforts
made
prepare
multifunctional
2D
TMDCs.
Язык: Английский
New thiadiazolopyrimidine-ornamented pyrazoles as prospective anticancer candidates via suppressing VEGFR-2/PI3K/Akt signaling pathway: Synthesis, characterization, in-silico, and in-vitro studies
International Journal of Biological Macromolecules,
Год журнала:
2024,
Номер
unknown, С. 138735 - 138735
Опубликована: Дек. 1, 2024
Язык: Английский
Design, synthesis, α-amylase and glucose diffusion inhibition, and molecular docking studies of new indenopyrazolones bearing benzothiazole derivatives
Bioorganic & Medicinal Chemistry Letters,
Год журнала:
2024,
Номер
103, С. 129692 - 129692
Опубликована: Март 5, 2024
Язык: Английский
Continuous Flow Synthesis of Five‐Membered N‐Heterocycles by Ynone System
Asian Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 18, 2024
Abstract
In
this
study,
we
devised
a
practical
and
effective
method
for
synthesizing
ynones
from
terminal
alkynes
anhydride
utilizing
continuous
flow
apparatus
at
ambient
temperature.
Moreover,
coupled
the
with
hydrazines,
hydroxylamine
hydrochloride
to
synthesize
pyrazole
isoxazole
derivatives.
This
protocol's
unique
characteristics
include
metal‐free
approach,
mild
reaction
conditions,
short
residence
time,
wide
range
of
functional
group
tolerance.
Sustainable
strategies
are
most
useful
affordable
than
conventional
benchtop
approaches.
Язык: Английский