Inhibition of DRP-1 mitochondrial mitophagy and fission by novel α-aminophosphonates bearing pyridine: synthesis, biological evaluations, and computer-aided design DOI Creative Commons
Hend A. Hekal, Maha M. Salem,

Hayam A. Abd El Salam

и другие.

BMC Chemistry, Год журнала: 2024, Номер 18(1)

Опубликована: Сен. 18, 2024

Язык: Английский

An updated review on 1,2,3-/1,2,4-triazoles: synthesis and diverse range of biological potential DOI

Anirudh Pratap Singh Raman,

M. Aslam, Amardeep Awasthi

и другие.

Molecular Diversity, Год журнала: 2024, Номер unknown

Опубликована: Июль 27, 2024

Язык: Английский

Процитировано

5
4-amino-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol as potent antimicrobial agent: Synthesis, X-ray, antimicrobial activity and computational studies DOI

Khouloud Rouzi,

Silvia Antonia Brandán,

Imane El Houssni

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1320, С. 139613 - 139613

Опубликована: Авг. 22, 2024

Язык: Английский

Процитировано

4
New Quinazolinone-1,2,4-Triazole Analogues: Synthesis, Anticancer Evaluation, Molecular Docking, and In Silico ADMET Prediction DOI

Anjanareddy Basava Reddy,

Tejeswara Rao Allaka, Vidya Sagar Reddy Avuthu

и другие.

Journal of Molecular Structure, Год журнала: 2025, Номер 1334, С. 141850 - 141850

Опубликована: Фев. 23, 2025

Язык: Английский

Процитировано

0
DHA-Indole-Triazole Hybrids: Click Mediated Synthesis, Antimicrobial, Antibiofilm and In Silico Studies DOI

Anshul Grover,

Aman Kumar, Priya Kumari

и другие.

Journal of Molecular Structure, Год журнала: 2025, Номер unknown, С. 141953 - 141953

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Recent Report on Indoles as a Privileged anti-viral Scaffold in Drug Discovery DOI

Asmita Singh,

Charu Bhutani,

Pankaj Khanna

и другие.

European Journal of Medicinal Chemistry, Год журнала: 2024, Номер 281, С. 117017 - 117017

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

1
Study on Preparation of Regenerated Cellulose Fiber from Biomass Based on Mixed Solvents DOI Open Access

Junjiang Xiao,

Pengcheng Li, Xiaotao Zhang

и другие.

Materials, Год журнала: 2024, Номер 17(4), С. 819 - 819

Опубликована: Фев. 8, 2024

In this study, Arundo donax Linnaeus was utilized as the biomass and a TH/DS (Tetra-n-butylammonium hydroxide/Dimethyl sulfoxide, C16H37NO/C2H6OS) system employed to dissolve cellulose. The optimal process for preparation of L. regenerated cellulose fiber determined through optimization. physical properties antimicrobial performance resulting products were analyzed. results demonstrated that indicators fiber, prepared from cellulose, met requirements standard Viscose Filament (Dry breaking strength ≥ 1.65 CN/dtex, Elongation at dry 15.5–26.0%, Dry elongation CV value ≤ 10.0%). Additionally, excellent exhibited by developed in with antibacterial rates against Staphylococcus aureus other three strain indexes meeting standards. Furthermore, high antiviral activity 99.99% H1N1 H3N2 strains influenza A virus observed experimental samples, indicating remarkable effect. Valuable references comprehensive utilization resources are provided research.

Язык: Английский

Процитировано

0
Natural products Compound Nutritional Value from Pelargonium graveolens DOI Creative Commons

Neveen A. El-wardany,

Mariam Ahmed Ali Abdel-Kader,

Eslam R. El‐Sawy

и другие.

Deleted Journal, Год журнала: 2024, Номер 10(2), С. 814 - 838

Опубликована: Апрель 15, 2024

Pelargonium graveolens (Family: Geraniaceae) was considered a medicinal with various medicinal, pharmaceutical and food applications. The ethanolic extract from this plant exhibited antimicrobial activities against different groups of test strains including Staphylococcus aureus (Gram-positive bacterium), Escherichia coli (Gram-negative Methicillin-resistant (MRSA) Candida albicans (yeast) as well the food-borne bacterial Salmonella typhimurium Listeria monocytogenes. minimum inhibitory concentration (MIC) bactericidal (MBC) were evaluated all microbes results indicated that MIC values between 19.53 78.125µg/ml. also had antibiofilm especially E. S. (78.125 µg/ml). Antioxidant phenolic content investigated revealing it high level (1160.62µgAAE/g dry extract) leading to total antioxidant activity (1104.46 µgGAE/g extract). GC/MS analysis revealed compounds Tartaric acid, bis-O-(trimethylsilyl)-, bis (trimethylsilyl) ester (15.52%), Spiro[cyclopropane-3-(3,4-dihydro-1h-2-thianaphthalene)] (10.60%), Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-(methoxymethyl)- (10.34%), Myo-inositol, 1,2,3,4,5,6-hexakis-o-(trimethylsilyl)- (8.21%), 8,9-Di(p-methoxyphenyl)-7,10-dimethyltricyclo[4.2.0.2(2,5)] deca-7,9-diene (6.05%), Butanedioic [(trimethylsilyl)oxy]-, bis(trimethylsilyl) (5.08%) dominant components in extract. HPLC contents showed gallic catechin, Naringenin chlorogenic major constituents Cytotoxic studies normal cell line IC50 value (179.55 µg/ml) concept is safe be used additive. addition P. affected sensory characteristics ice cream. It makes difference control's overall acceptability or appearance, flavor, texture, color. Ice cream supplemented 10% 15% scored excellent attributes. In addition, color acceptance over control 5%.

Язык: Английский

Процитировано

0
Inhibition of DRP-1 mitochondrial mitophagy and fission by novel α-aminophosphonates bearing pyridine: synthesis, biological evaluations, and computer-aided design DOI Creative Commons
Hend A. Hekal, Maha M. Salem,

Hayam A. Abd El Salam

и другие.

BMC Chemistry, Год журнала: 2024, Номер 18(1)

Опубликована: Сен. 18, 2024

Язык: Английский

Процитировано

0