Development and Characterization of Polylactic Acid/Chitosan Based Polymeric Bio-Nanocomposites Reinforced with Hydroxyapatite and Aluminum Oxide Bifiller for Biomedical Application

Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 27, 2025

Язык: Английский

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Calcium Phosphate Biomaterials Modified with Mg2+ or Mn2+ Ions: Structural, Chemical, and Biological Characterization

Ceramics International, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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Integrated PLA/LLDPE nanocomposites with compatibilizer and hydroxyapatite-zinc oxide: mechanical, physical, thermal, and morphological properties

South African Journal of Chemical Engineering, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Titanium alloy-based hydroxyapatite composites in sports injury repair: Preparation, Application, and Prospects

Journal of Alloys and Compounds, Год журнала: 2025, Номер unknown, С. 180416 - 180416

Опубликована: Апрель 1, 2025

Язык: Английский

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Production of hydroxyapatite coating on 3D printed PLA parts by powder bed annealing

Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Май 8, 2025

The development of effective and biocompatible coatings for polymeric implants is crucial advancing orthopedic solutions. This study investigates the feasibility employing powder bed annealing to deposit hydroxyapatite (HA) on 3D-printed polylactic acid (PLA) parts. proposed method provides a cost-effective scalable alternative conventional coating techniques. experimental process involved immersing PLA parts in submicrometric ceramic followed by thermal treatment induce adhesion diffusion HA particles into polymer surface. results demonstrated that successfully generated uniform particulate coating, significantly enhancing surface roughness, wettability, hydrophilicity substrate. Mechanical characterization revealed an increase flexural strength microhardness, while maintaining impact resistance. However, slight reduction ductility was observed. Biocompatibility tests confirmed coated samples supported cell proliferation, suggesting their potential promoting osseointegration biomedical applications. Compared existing methods, allows direct integration bioactive onto without requiring complex post-processing. Additionally, combination PLA’s biodegradability with HA’s osteoinductive properties suggests promising applications resorbable bone regeneration. contributes ongoing innovation coatings, offering practical pathway accessible personalized implants.

Язык: Английский

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Optimization of Compressive Strength Properties in Fused Deposition Modeling 3D Printed PLA/HA Composites for Bone Tissue Engineering Applications

Engineering Reports, Год журнала: 2025, Номер 7(5)

Опубликована: Май 1, 2025

ABSTRACT This study investigates the optimization of 3D‐printed polylactic acid (PLA) and hydroxyapatite (HA) composites for biomedical applications, focusing on enhancing mechanical properties through process parameter surface modification. The response methodology (RSM), along with post hoc statistical validation using Tukey's HSD test, was employed to evaluate influence nozzle temperature (200°C–240°C), layer height (0.1–0.3 mm), HA filler ratio (3–9 wt%) compressive strength both untreated chemically treated composites. Silane treatment applied improve interfacial bonding, resulting in a 5%–7% increase compared samples. optimal conditions (240°C, 9% HA, 0.3 mm thickness) yielded maximum 75.35 MPa 71.42 Statistical analysis confirmed that thickness content significantly influenced performance. Contour plots 3D surfaces were also incorporated visualize interactions. Comparison other techniques demonstrated RSM effectively minimized experimental runs while achieving superior properties. These findings suggest modified PLA/HA are promising candidates load‐bearing applications.

Язык: Английский

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The use of poly(lactic acid) (PLA) in bone tissue engineering

Open Journal of Nano, Год журнала: 2025, Номер 10(1), С. 1 - 13

Опубликована: Март 27, 2025

Bone is a tissue that can regenerate and repair itself when minor damage occurs; however, it insufficient to large defects. Today, various treatments bone defects are limited due risks such as lack of donors, genetic differences, infection, rejection. Although traditional metals used extensively in treatments, these materials have many disadvantages. In recent years, biodegradable biopolymers poly(lactic) acid (PLA), polyetheretherketone (PEEK), polycaprolactone (PCL), poly (glycolic acid) PGA attracted growing interest their properties lightweight, high mechanical strength, biocompatibility, processability. polymer been the medical field. PLA known be preferred engineering applications biomaterial supports cell processes, including migration, proliferation, distribution, differentiation. alongside methods for producing scaffolds, innovative technological approaches emerged. Traditional manufacturing methods, often precise control over scaffold porosity, prompting shift towards advanced designs rapid prototyping techniques. scaffolds produced with additive manufacturing, possible create 3D porous internal connections. addition, PLA-based composite studied improve biological pure osteogenicity, strength. This study presents review applications.

Язык: Английский

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Inclusion of modified nano-magnesium hydroxide as an adjuvant flame retardant in the development of PLA/hydroxyapatite nanocomposites

Heliyon, Год журнала: 2024, Номер 10(20), С. e39529 - e39529

Опубликована: Окт. 1, 2024

For the preparation of thermal stable and flame-retardant polylactic acid (PLA) nanocomposites two new modified nano-structures including imide-carboxylated chitosan Mg(OH)

Язык: Английский

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Nano-hydroxyapatite (n-HAP) from Pangasius bone side streams and its application as a reinforcing agent in biodegradable food packaging films

Sustainable Food Technology, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

The bone side streams from catfish ( Pangasianodon hypophthalmus ) were used to produce nano-hydroxyapatite (n-HAP) by a calcination method.

Язык: Английский

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Fabrication of SS 316L particle-infilled PLA composite filaments from cast-off bi-material extrudates for 3D printing applications

Waste Management, Год журнала: 2024, Номер 193, С. 386 - 397

Опубликована: Дек. 20, 2024

Язык: Английский

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