The Most Up-to-Date Advancements in the Design and Development of Urease Inhibitors (January 2020–March 2024) DOI

Danial Babaei,

Ebrahim Saeedian Moghadam, Latifeh Navidpour

и другие.

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 9, 2025

The aim of this review is to address the most up-to-date information on design and development, structure–activity relationship (SAR), molecular docking study novel effective urease inhibitors between January 2020 March 2024. Herein, importance substituents their effect bioactivity reported compounds have been investigated. Besides, relation important residues inside active site enzyme for interactions has also reviewed. This classified into main scaffolds, namely, barbiturates, thiobarbiturates, Schiff bases, semicarbazides, thiosemcarbazides, benzimidazoles, 1,3,4-thiadiazoles, 1,3,4-oxadiazoles, provide better insight newly developed inhibitors.

Язык: Английский

Design, synthesis, and in-Silco ADME prediction of some novel bis(1,3,4-thiadiazoles) encapsulated lipid chitosan nano capsule decorative with magnetic nanoparticles and their potential anti-helicobacter pylori activity DOI
Mostafa E. Salem, Ahmed H. M. Elwahy, Hamdi M. Hassaneen

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 139746 - 139746

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

1
The Most Up-to-Date Advancements in the Design and Development of Urease Inhibitors (January 2020–March 2024) DOI

Danial Babaei,

Ebrahim Saeedian Moghadam, Latifeh Navidpour

и другие.

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 9, 2025

The aim of this review is to address the most up-to-date information on design and development, structure–activity relationship (SAR), molecular docking study novel effective urease inhibitors between January 2020 March 2024. Herein, importance substituents their effect bioactivity reported compounds have been investigated. Besides, relation important residues inside active site enzyme for interactions has also reviewed. This classified into main scaffolds, namely, barbiturates, thiobarbiturates, Schiff bases, semicarbazides, thiosemcarbazides, benzimidazoles, 1,3,4-thiadiazoles, 1,3,4-oxadiazoles, provide better insight newly developed inhibitors.

Язык: Английский

Процитировано

0