Sustainable materials and technologies, Год журнала: 2025, Номер unknown, С. e01395 - e01395
Опубликована: Апрель 1, 2025
Язык: Английский
Environmental Nanotechnology Monitoring & Management, Год журнала: 2025, Номер unknown, С. 101062 - 101062
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown
Опубликована: Март 21, 2025
Orthopedic implants play a vital role in restoring function patients with bone and joint disorders, yet improving their biocompatibility mechanical strength remains challenge. This study evaluates the vivo performance of 3D-printed poly L-lactic acid (PLA) AZ31 magnesium (Mg) alloy coated titanium-zirconium (Ti-Zr) titanium hydroxyapatite (Ti-HA) nanocomposites using Wistar rat model. The implants' degradation rates over 60 days were observed, Mg showing reduced (25 32%, respectively) compared to uncoated materials. Nano-CT analysis confirmed progressive regeneration, healing from 10-15% at day 30 60-70% 60. Histological revealed osteoblast osteoclast activity, indicating effective remodeling. These findings suggest that Ti-Zr Ti-HA nanocomposite-coated offer enhanced corrosion resistance, stability, biocompatibility. study's potential enhance efficacy orthopedic therapies advance creation functional fulfill patient requirements superior performance, durability, compliance. Further optimization may establish these coatings as promising candidates for clinical applications.
Язык: Английский
Процитировано
0
Journal of Materials Research and Technology, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Journal of Applied Polymer Science, Год журнала: 2025, Номер unknown
Опубликована: Апрель 8, 2025
ABSTRACT This study presents the development of a biodegradable composite scaffold designed to address limitations associated with conventional bone repair materials. 3D‐printing filaments were developed using fish scale powder (FSP) or scale‐derived hydroxyapatite (HAP), polylactic acid (PLA), and polycaprolactone (PCL), focus on optimal effect 5 wt% HAP mechanical properties PLA. Composite scaffolds further prepared by integrating 3D‐printed grid chitosan/gelatin hydrogels through vacuum freeze‐drying. The evaluated property tests, thermal analysis (including DSC TGA), absorption rate assessments (conducted via immersion experiments in various solutions), surface morphology analyses (utilizing SEM EDS). results show that addition significantly improves filaments. high exhibited HAP/PLA suggests improved biocompatibility its potential for vivo tissue fluid absorption. showed visible mineralization degradation after 10 days simulated body (SBF), highlighting regeneration.
Язык: Английский
Процитировано
0
Sustainable materials and technologies, Год журнала: 2025, Номер unknown, С. e01395 - e01395
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0