A tandem approach for the synthesis of 1-phenyl-pyrazolo-quinolinones by Fe ₃ O ₄ @MWCNT nanocomposite as heterogeneous catalyst

Green Chemistry Letters and Reviews, Год журнала: 2025, Номер 18(1)

Опубликована: Янв. 10, 2025

A simple, facile, efficient and highly promising protocol for the synthesis of 1-phenyl-pyrazolo-quinolinone analogs using Fe3O4@MWCNT nano-composite as a catalyst via Knoevenagel–Michael reaction has been developed. The use several advantages, like simple preparation, inexpensive, handling, high stability. It was synthesized from MWCNT iron oxide thoroughly characterized BET, PXRD, SEM, TEM, TGA analysis. All target molecules were confirmed by various spectroscopic techniques such 1H-NMR, 15N-NMR, 13C-NMR, HRMS. present work unveils environmentally friendly approach synthesizing phenyl-pyrazolo-quinolinone scaffolds with higher yields (93–97%), selectivity, efficiency, mild conditions, no need chromatographic separation, short times, recovery reuse minimum seven cycles is possible without causing notable reduction in product yields. method complies green chemistry principles presents feasible alternative to previously documented techniques.

Язык: Английский

1,4-Naphthoquinone thiazoles: Synthesis, crystal structure, anti-proliferative activity, and inverse molecular docking study

Journal of Molecular Structure, Год журнала: 2024, Номер 1322, С. 140330 - 140330

Опубликована: Окт. 9, 2024

Язык: Английский

Design, synthesis, characterization and biological evaluation of coumarin bound 1,2,3-triazoles using click chemistry

Synthetic Communications, Год журнала: 2024, Номер unknown, С. 1 - 20

Опубликована: Сен. 26, 2024

Язык: Английский