Gelatin/PLA-loaded gold nanocomposites synthesis using Syzygium cumini fruit extract and their antioxidant, antibacterial, anti-inflammatory, antidiabetic and anti-Alzheimer’s activities

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 15, 2025

Nanotechnology has experienced significant advancements, attracting considerable attention in various biomedical applications. This innovative study synthesizes and characterizes Ge/PLA/AuNCs (gelatin/PLA/gold nanocomposites) using Syzygium cumini extract to evaluate their The UV–Visible spectroscopy results an absorption peak at 534 nm were primarily confirmed by synthesis. FTIR spectrum showed functional groups the XRD patterns crystalline shape structure of nanocomposites. FESEM HRTEM a oval with average particle size 21 nm. Ge/PLA/AuNC's remarkable antioxidant activity, as evidenced DPPH (70.84 ± 1.64%), ABTS activity (86.17 1.96%), reducing power (78.42 1.48%) concentration 100 μg/mL was observed. zone inhibition against Staphylococcus aureus (19.45 0.89 mm) Echericia coli (20.83 0.97 revealed excellent antibacterial Ge/PLA/AuNCs. anti-diabetic supported α-amylase (82.56 1.49%) α-glucosidase (80.27 1.57%). anti-Alzheimer AChE (76.37 1.18%) BChE (85.94 1.38%) enzymes. In vivo studies zebrafish embryos that have biocompatibility nontoxicity. SH-SY5Y cell line demonstrated improved viability (95.27 1.62%) enhanced neuronal growth following treatment. conclusion, present highlights cost-effective non-toxic properties Furthermore, it presents attractive promising approach for future

Язык: Английский

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Phytofabrication of copper nanoparticles using Momordica cymbalaria fruit extract and their antibacterial, antioxidant and anti-inflammatory properties

Hybrid Advances, Год журнала: 2025, Номер unknown, С. 100421 - 100421

Опубликована: Фев. 1, 2025

Язык: Английский

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Synergistic Synthesis of Copper Nanoparticles via Bioactive Compounds from Acacia auriculiformis: Embryonic Toxicology and In Vitro Antioxidant Evaluation

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

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Green Approach for the Purification of the Bioactive Compound Saponin from the Root Extract of Argemone mexicana and the Evaluation of Antioxidant, Antimicrobial, Anti-inflammatory and Anticancer Activities

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Фев. 24, 2025

Язык: Английский

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Biosynthesis of Cerium Oxide Nanoparticles Using Alternanthera sessilis Leaf Extract and Evaluation of their Antioxidant, Antibacterial, Anti-Inflammatory, Antidiabetic and Cytotoxic Activities

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Март 4, 2025

Язык: Английский

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Utilization of mistletoe for the synthesis of copper nanoparticles and its clinical applications

European Journal of Chemistry, Год журнала: 2025, Номер 16(1), С. 53 - 63

Опубликована: Март 31, 2025

Nanoparticles are substances with dimensions smaller than 100 nm. Nowadays, nanoparticles can be synthesized by many methods. Copper (CuNPs) were made using the green synthesis approach, aqueous extracts of pine mistletoe plant (Viscum album ssp. austriacum) and CuSO₄ metal salt. The formation CuNPs was determined both observing color change UV-vis method. Especially peaks observed around leaf (567 nm), fruit (560 branch (565 nm). Specific functional groups involved in reduction Cu0 FT-IR spectroscopy. In addition, SEM EDS analyses show that they nanosized their average size is less particular, it fruit-derived smallest (between 23.21 54.63 all spherical shape. antioxidant capacities these from them investigated. For this purpose, DPPH• ABTS•+ radical scavenging activities samples determined. IC50 value obtained extract as 151.41 µg/mL, 160.43 µg/mL. results compared standard ascorbic acid results. Furthermore, copper found to have highest activity. antimicrobial examined. antiquorum activity parts V. for first time. As a result, had superior properties.

Язык: Английский

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Biosynthesis and Characterization of Cymodocea serrulata-aided Copper Oxide Nanoparticles and an Evaluation of its Antibacterial Properties

Thalassas An International Journal of Marine Sciences, Год журнала: 2025, Номер 41(2)

Опубликована: Май 10, 2025

Язык: Английский

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Phenylboronic acid-functionalized copper nanoclusters with sensitivity and selectivity for the ratiometric detection of luteolin

Bioorganic Chemistry, Год журнала: 2024, Номер 153, С. 107946 - 107946

Опубликована: Ноя. 7, 2024

Язык: Английский

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