Advances in chemical and materials engineering book series,
Год журнала:
2024,
Номер
unknown, С. 349 - 392
Опубликована: Ноя. 22, 2024
This
chapter
is
focused
on
describing
the
latest
advances
related
to
development
of
bio-piezoelectric
coatings
for
bone
regeneration
applications.
It
starts
with
description
main
concepts
about
bioelectrical
phenomena
in
human
body
and
its
role
bone.
explains
such
as
dielectric
electrical
responses
that
includes
piezoelectricity,
pyroelectricity,
ferroelectricity
how
can
present
these
types
phenomena.
The
also
definition
bio-ceramic
materials
bioactive
coatings,
a
summary
employed
nowadays
applications
tissue
regeneration.
Also,
this
review
engineering
future
perspectives
topic.
Overall,
reviewing
comprehensively
response
natural
tissues
relevance
ceramics
International Journal of Extreme Manufacturing,
Год журнала:
2024,
Номер
7(2), С. 022002 - 022002
Опубликована: Ноя. 14, 2024
Highlights
Exploring
personalized
biomedical
metal
implants
through
additive
manufacturing
(AM).
Presenting
new
load-bearing
and
biodegradable
alloys
for
implants.
Showcasing
AI
4D
printing
advancements
in
material
properties.
AM’s
roles
various
medical
fields.
Highlighting
perspectives
of
implant
technology
improved
patient
care.
The
rapid
corrosion
rate
of
biodegradable
Magnesium
(Mg)
implants
in
physiological
environments
compromises
their
mechanical
integrity
and
inhibit
bone
healing.
To
improve
the
magnesium
alloy
AZ31's
resistance
bioactivity,
this
study
applies
bi-layered
coatings
hydroxyapatite
(HA)
beta-tricalcium
phosphate
(β-TCP).
high-velocity
oxygen
fuel
(HVOF)
spraying
technique
has
developed
HA/TCP
with
superior
adhesion,
low
porosity,
high
density.
These
form
a
protective
barrier
against
simulated
body
fluid
(SBF),
significantly
enhancing
resistance.
on
AZ31
substrates,
thickness
42.6
µm
crystallinity
(>70%),
reduced
current
density
(Icorr)
from
174.03
µA/cm2
to
30.25
µA/cm2,
decreasing
3.98
mm/year
0.69
mm/year.
According
EIS
testing,
coated
sample's
charge
transfer
(Rct)
increased
147.47
Ω·cm2
1539.38
Ω·cm2.
SEM
EDS
analysis
revealed
that
after
ten
days
immersion,
there
was
reduction
Ca/P
ratio
1.51
1.27,
indicating
dissolution
coating.
examination
confirmed
formation
an
apatite
layer,
which
validated
surface
bioactivity.
results
suggest
substantially
Mg
implants'
activity
biodegradation
capabilities,
making
them
promising
candidates
for
advanced
biomedical
applications.
Journal of Biomaterials Science Polymer Edition,
Год журнала:
2025,
Номер
unknown, С. 1 - 27
Опубликована: Фев. 7, 2025
In
orthopaedic
clinical
applications,
creating
biocomposite
bone
substitutes
to
take
the
place
of
autologous
transplants
is
still
difficult.
Studies
have
demonstrated
for
decades
that
poly
(lactic-co-glycolic
acid)
[PLGA],
a
common
polymer,
has
many
benefits
make
it
strong
contender
replacement.
These
include
biodegradability,
good
mechanical
qualities,
and
ability
induce
new
production.
Although
calcium-based
materials
are
frequently
used
as
fillers
in
implantation,
efficiency
ceramic
containing
calcium
may
be
hampered
by
number
issues,
including
low
microporosity
quick
rates
degradation.
order
overcome
these
obstacles,
scientists
investigating
ways
improve
implant
performance
combining
PLGA
with
other
materials,
especially
terms
encouraging
improved
connections
nearby
cells.
An
overview
chemical
properties
different
PLGA-based
scaffold
composites,
well
drawbacks
PLGA-Calcium
implants
tissue
engineering
goals
this
review.
It
also
highlights
possible
advantages
consequences
using
3D
printing
technology
outcomes.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 28, 2025
Abstract
Calcium
phosphates
(CaPs)
are
ubiquitous
in
biological
structures,
such
as
vertebrate
bones
and
teeth,
have
been
widely
used
biomedical
applications.
However,
fabricating
CaPs
at
the
nanoscale
3D
has
remained
a
significant
challenge,
particularly
due
to
limitations
current
nanofabrication
techniques,
two‐photon
polymerization
(2pp),
which
not
applicable
for
creating
CaP
nanostructures.
In
this
study,
novel
approach
is
presented
print
structures
with
unprecedented
resolution
of
≈300
nm
precision,
achieving
level
detail
three
orders
magnitude
finer
than
any
existing
additive
manufacturing
techniques
CaPs.
This
advancement
achieved
by
leveraging
bioinspired
chemistry,
utilizing
bone
prenucleation
nanoclusters
(PNCs,
average
size
5
nm),
within
photosensitive
resin.
These
form
highly
transparent
photoresist,
overcoming
light‐scattering
typically
associated
larger
calcium
phosphate‐based
nanoparticles.
method
only
allows
nanopatterning
on
diverse
substrates,
but
also
enables
precise
control
microstructure
down
submicron
grains.
The
paves
way
developing
metamaterials,
lightweight
damage‐tolerant
materials,
cell‐modulating
interfaces,
precision‐engineered
coatings.
Polymers,
Год журнала:
2025,
Номер
17(7), С. 935 - 935
Опубликована: Март 29, 2025
Bone
tissue
engineering
aims
to
restore
lost
bone
and
create
an
environment
conducive
new
formation.
To
address
this
challenge,
we
developed
a
novel
biomimetic
hydrogel
that
combines
maleic
anhydride-modified
type
I
collagen
(ColME)
with
demineralized
decellularized
porcine
matrix
particles
(mDBMp),
forming
composite
ColME-mDBMp
(CMB)
hydrogel.
Chemical
modification
of
resulted
in
high
degree
substitution,
thereby
enhancing
its
photocrosslinkability.
Integration
mDBMp
into
the
ColME
via
photocrosslinking
enhanced
physiological
stability,
reduced
shrinkage,
improved
mechanical
strength
compared
gelatin
methacrylate
(GelMA)-based
hydrogels.
Moreover,
mineralization
CMB
promoted
formation
pure
hydroxyapatite
(HAp)
crystals,
providing
superior
stiffness
while
maintaining
ductility
relative
GelMA-based
In
vitro,
human
marrow
mesenchymal
stem
cells
(hBMSCs)
encapsulated
hydrogels
exhibited
proliferation,
cell-matrix
interactions,
osteogenic
differentiation,
as
evidenced
by
increased
calcium
deposition
histological
analysis.
These
results
demonstrate
hydrogel,
enriched
extracellular
(ECM)
components,
shows
considerable
promise
over
current
for
engineering.
