Biomimetic Structural Design in 3D-Printed Scaffolds for Bone Tissue Engineering

Materials Today Bio, Год журнала: 2025, Номер 32, С. 101664 - 101664

Опубликована: Март 14, 2025

Язык: Английский

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Smart biomaterials in healthcare: Breakthroughs in tissue engineering, immunomodulation, patient-specific therapies, and biosensor applications

Applied Physics Reviews, Год журнала: 2025, Номер 12(1)

Опубликована: Март 1, 2025

Smart biomaterials have significantly impacted human healthcare by advancing the development of medical devices designed to function within tissue, mimicking behavior natural tissues. While intelligence has evolved from inert active over past few decades, smart take this a step further making their surfaces or bulk respond based on interactions with surrounding tissues, imparting outcomes similar tissue functions. This interaction helps in creating stimuli-responsive biomaterials, which can be useful engineering, regenerative medicine, autonomous drug delivery, orthopedics, and much more. Traditionally, material engineering focused refining static properties accommodate them body without evoking an immune response, was major obstacle unrestricted operation. review highlights explains various approaches currently under research for developing that tune responses bodily factors like temperature, pH, ion concentration external magnetism, light, conductivity. Applications soft hard 4D printing, scaffold design are also discussed. The advanced application microfluidics, organ-on-a-chip models, extensively benefits intrinsic discussed below. elaborates how biomaterial could revolutionize biosensor applications, thereby improving patient care quality. We delineate limitations key challenges associated providing insights into path forward outlining future directions next-generation will facilitate clinical translation.

Язык: Английский

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Plant Polyphenol‐Based Injectable Hydrogels: Advances and Biomedical Applications

Advanced Healthcare Materials, Год журнала: 2025, Номер unknown

Опубликована: Март 27, 2025

Plant polyphenol-based hydrogels, known for their biocompatibility and adhesive properties, have emerged as promising materials in biomedical applications. These hydrogels leverage the catechol group's ability to form stable bonds moist environments, similar mussel proteins. This review provides a comprehensive overview of synthesis, adhesion mechanisms, applications, particularly wound healing, tissue regeneration, drug delivery. However, challenges related vivo stability long-term remain critical barriers clinical translation. Future research should focus on enhancing bioactivity, biocompatibility, scalability these while addressing concerns toxicity, immune responses, large-scale manufacturing. Advances artificial intelligence-assisted screening 3D/4D bioprinting are expected accelerate development Furthermore, integration biomimetic designs responsive functionalities, such pH or temperature sensitivity, holds promise further improving therapeutic efficacy. In conclusion, multifunctional plant represents frontier advancing personalized medicine minimally invasive treatments.

Язык: Английский

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Additive Manufacturing in Biomedical: Applications, Challenges, and Prospects

Hybrid Advances, Год журнала: 2025, Номер unknown, С. 100467 - 100467

Опубликована: Март 1, 2025

Язык: Английский

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Tough, Wide-Temperature-Resistant, and Water-Retentive Conductive Hydrogel for Human Motion Sensing

ACS Applied Polymer Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 3, 2025

Язык: Английский

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