Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical Applications
Gels,
Год журнала:
2025,
Номер
11(4), С. 271 - 271
Опубликована: Апрель 5, 2025
Collagen-based
wound
dressings
have
developed
as
an
essential
component
of
contemporary
care,
utilizing
collagen’s
inherent
properties
to
promote
healing.
This
review
thoroughly
analyzes
collagen
dressing
advances,
examining
different
formulations
such
hydrogels,
films,
and
foams
that
enhance
care.
The
important
processes
by
which
promotes
healing
(e.g.,
promoting
angiogenesis,
encouraging
cell
proliferation,
offering
structural
support)
are
discussed
clarify
its
function
in
tissue
regeneration.
effectiveness
adaptability
demonstrated
via
clinical
applications
investigated
acute
chronic
wounds.
Additionally,
commercially
accessible
collagen-based
skin
treatments
discussed,
demonstrating
their
practical
use
healthcare
settings.
Despite
the
progress,
study
discusses
obstacles
restrictions
encountered
producing
adopting
dressings,
difficulties
manufacturing
financial
concerns.
Finally,
current
landscape’s
insights
indicate
future
research
possibilities
for
optimization,
bioactive
agent
integration,
overcoming
existing
constraints.
analysis
highlights
potential
innovations
improve
treatment
methods
patient
Язык: Английский
The potential of collagen-based materials for wound management – An example of a larger problem
Materials Today Chemistry,
Год журнала:
2025,
Номер
44, С. 102561 - 102561
Опубликована: Фев. 18, 2025
Язык: Английский
Valorization of hazardous leather shaving dust for the fabrication of electrospun collagen/PVA/chitosan nanomats in wound care
Carbohydrate Polymer Technologies and Applications,
Год журнала:
2025,
Номер
unknown, С. 100748 - 100748
Опубликована: Март 1, 2025
Язык: Английский
Fluorene-bridged viologen derivatives exhibiting strong fluorescence and electrochromic properties
Materials Today Chemistry,
Год журнала:
2025,
Номер
45, С. 102697 - 102697
Опубликована: Апрель 1, 2025
Язык: Английский
Recent Advances in the Development and Application of Cell-Loaded Collagen Scaffolds
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(9), С. 4009 - 4009
Опубликована: Апрель 24, 2025
Tissue
engineering
techniques
aim
to
improve
or
replace
biological
tissues
organs
by
utilizing
the
extracellular
matrix
facilitate
repair
of
damaged
organs.
Collagen-based
scaffolds
offer
numerous
advantages,
including
excellent
biocompatibility,
low
immunogenicity,
biodegradability,
hemostatic
properties,
and
mechanical
strength.
Collagen
can
reconstruct
microenvironment,
promote
cell
adhesion,
migration,
proliferation,
differentiation,
play
a
critical
role
in
cell-to-cell
cell-to-matrix
interactions.
has
been
extensively
utilized
tissue
organ
reconstruction.
This
review
examines
properties
collagen,
its
composition,
structure,
characteristics,
regulating
various
cellular
behaviors.
Additionally,
preparation
cell-loaded
collagen
is
discussed,
along
with
comprehensive
overview
their
applications
tissues,
skin,
nerve,
bone/cartilage,
heart,
liver,
others.
Emerging
strategies
future
perspectives
for
clinical
are
also
presented.
provides
synthesis
mechanisms
underlying
use
as
advanced
biomaterials,
emphasizing
potential
expand
collagen.
Язык: Английский
Two Novel Membranes Based on Collagen and Polyphenols for Enhanced Wound Healing
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(22), С. 12353 - 12353
Опубликована: Ноя. 18, 2024
Two
novel
membranes
based
on
collagen
and
two
polyphenols,
taxifolin
pentaglutarate
(TfG5)
a
conjugate
of
with
glyoxylic
acid
(DfTf),
were
prepared.
Fourier
transform
infrared
spectroscopy
examination
confirmed
the
preservation
triple
helical
structure
collagen.
A
scanning
electron
microscopy
study
showed
that
both
materials
had
porous
structure.
The
incorporation
DfTf
into
freeze-dried
matrix
increased
aggregation
fibers
to
higher
extent
than
TfG5,
resulting
in
more
compact
material
containing
DfTf.
It
was
found
NIH/3T3
mouse
fibroblasts
attached
to,
relatively
evenly
spread
out
on,
surface
newly
obtained
membranes.
In
addition,
it
shown
enhanced
skin
wound
healing
rats
chemical
burn
induced
by
acetic
acid.
treatment
led
faster
reepithelization
granulation
tissue
formation
compared
use
other
agents
(collagen
without
polyphenols
buffer
saline).
also
that,
tissue,
level
thiobarbituric
reactive
substances
(TBARS)
significantly
low-molecular-weight
SH-containing
compounds
(RSH)
lower
those
healthy
skin,
indicating
rise
oxidative
stress
at
site
injury.
decreased
TBARS
RSH
level,
suggesting
antioxidant/anti-inflammatory
effect
materials.
membrane
TfG5
effective
ones
(the
polyphenols).
On
whole,
data
indicate
have
potential
as
powerful
therapeutic
for
wounds.
Язык: Английский