Effect of glyoxal concentration and nanoparticles reinforcement on the functional properties of composite hydrogel for biomedical applications

Macromolecular Research, Год журнала: 2025, Номер unknown

Опубликована: Янв. 8, 2025

Язык: Английский

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Designing and synthesis of injectable hydrogel based on carboxymethyl cellulose/carboxymethyl chitosan containing QK peptide for femoral head osteonecrosis healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 270, С. 132127 - 132127

Опубликована: Май 7, 2024

Язык: Английский

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Geranium essential oil downregulates virulence genes and mitigates MRSA wound infections through a multifunctional hydrogel

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 310, С. 143197 - 143197

Опубликована: Апрель 17, 2025

Язык: Английский

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Crosslinking gelatin with robust inherent antibacterial natural polymer for wound healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 280, С. 136144 - 136144

Опубликована: Сен. 30, 2024

Язык: Английский

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Advances in Chitosan Derivatives: Preparation, Properties and Applications in Pharmacy and Medicine

Gels, Год журнала: 2024, Номер 10(11), С. 701 - 701

Опубликована: Окт. 29, 2024

Chitosan (CS) derivatives have been extensively investigated to enhance the physicochemical and biological properties of CS, such as its solubility, biocompatibility, bioactivity, which are required in various areas pharmacy medicine. The present work emphasizes ongoing research development this field, suggesting that further exploration CS could lead innovative solutions benefit society. properties, activities, methods preparation, advantages, limitations, intended application areas, realized practical implementations particular summarized discussed herein. Despite numerous promising attributes reported paper, however, challenges like target selectivity, standardization (purity, chitosan structural variability), cost-effectiveness still need addressing for widespread implementation, especially drug delivery. Therefore, basic studies prevail delivery systems. However, specific applications wound healing tissue engineering, practice found be more frequent. To obtain a complex view topic, information from scientific papers reviewed is supplemented with actual patents clinical studies. Both advances most successful important medical concerning future perspectives.

Язык: Английский

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Carboxymethyl chitosan: Synthesis, functional properties, and applications in sustainable food packaging material

Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2024, Номер 23(6)

Опубликована: Ноя. 1, 2024

Abstract Global environmental concerns about non‐degradable packaging materials are increasing. Carboxymethyl chitosan (CMCS), a polysaccharide widely used in the food industry, has gained attention field of packaging. Due to its biodegradability, film‐forming ability, and biocompatibility, CMCS emerged as sustainable option for degradable functional materials, offering solutions plastic pollution waste issues. This review explores delivery material, detailing synthesis methods, optimal preparation conditions, properties post‐carboxymethylation, applications alongside safety assessments. It summarizes physicochemical interactions CMCS‐based composites their impact on relevant properties, highlighting CMCS's potential green strategy smart active materials. Additionally, it presents latest advancements industry over past decade. exhibits good biocompatibility antibacterial functionality films is enhanced through modification polymerization. matrix preservation or coatings carrier ingredients, thereby improving encapsulation efficiency storage stability components. comprehensively outlines filling gaps existing literature, laying theoretical foundation development technology. provides reference further research, emphasizing need investigate molecular structure chemical optimize safety, fully tapping into industry.

Язык: Английский

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Comparison of two hemostatic skin adhesive dressings, incorporating multi-metal bioactive glass

Engineered Regeneration, Год журнала: 2024, Номер unknown

Опубликована: Июль 1, 2024

Current bioadhesive dressings, though potential in wound care, often exhibit inadequate adhesion and lack essential properties for optimal healing, such as being antibacterial, hemostatic, angiogenic. While various scaffolds containing natural adhesive molecules 3,4-dihydroxyphenyl-l-alanine (DOPA) tannic acid (TA) have been individually assessed, the comparison of adhesives these are scarcely studied. This study addresses limitations by developing two innovative composite hydrogel adhesives, based on DOPA TA, which integrated with novel multi-metal bioactive glass nanoparticles (BGNs). A comprehensive their was conducted to evaluate improving healing outcomes. BGNs were synthesized using sol-gel approach, yielding an amorphous porous structure. Incorporation 10% w/w uniform distribution enhanced mechanical both hydrogels, TA-based dressings demonstrating superior performance. demonstrated biocompatibility hemocompatibility, outperformed DOPA-based cell viability antibacterial activity against Staphylococcus aureus Escherichia coli, while composites showed better vitro angiogenic hemostatic capabilities. Regarding vivo investigations, mice model full-thickness skin wounds, DOPA- incorporated dressing contained BGN exhibited slightly performance re-epithelialization, collagen formation blood vessel density, indicating its acute applications.

Язык: Английский

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Rheological study of pullulan-pectin mixtures to prepare gel beads using the drip method and evaluation as gallic acid release systems

Food Hydrocolloids, Год журнала: 2024, Номер 160, С. 110747 - 110747

Опубликована: Окт. 18, 2024

Язык: Английский

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