Green Synthesis of Metal and Metal Oxide Nanoparticles: A Review of the Principles and Biomedical Applications

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(20), С. 15397 - 15397

Опубликована: Окт. 20, 2023

In recent years, interest in nanotechnology has increased exponentially due to enhanced progress and technological innovation. tissue engineering, the development of metallic nanoparticles been amplified, especially their antibacterial properties. Another important characteristic metal NPs is that they enable high control over features developed scaffolds (optimizing mechanical strength offering controlled release bioactive agents). Currently, main concern related method synthesis oxide environmental impact. The physical chemical uses toxic agents could generate hazards or exert carcinogenicity/environmental toxicity. Therefore, a greener, cleaner, more reliable approach needed. Green synthetic come as solution counter aforementioned limitations. Nowadays, green preferred because it leads prevention/minimization waste, reduction derivatives/pollution, use non-toxic (safer) solvents. This not only biomass sources reducing for salts. biomolecules also cover synthesized act situ capping agents. Further, involvement formation process reduces toxicity, prevents nanoparticle agglomeration, improves antimicrobial activity nanomaterial, leading possible synergistic effect. study aims provide comprehensive review nanoparticles, from routes, selected solvents, parameters latest application biomedical field.

Язык: Английский

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A Mechanistic Overview on Green Assisted Formulation of Nanocomposites and Their Multifunctional Role in Biomedical Applications

Heliyon, Год журнала: 2025, Номер 11(3), С. e41654 - e41654

Опубликована: Янв. 8, 2025

The importance of nanocomposites constantly attains attention because their unique properties all across the fields especially in medical perspectives. study green-synthesized has grown to be extremely fascinating field research. Nanocomposites are more promising than mono-metallic nanoparticles they exhibit synergistic effects. This review encapsulates current development formulation plant-mediated by using several plant species and impact secondary metabolites on biocompatible functioning. Phyto-synthesis produces diverse nanomaterials with biocompatibility, environment-friendliness, vivo actions, characterized varying sizes, shapes, biochemical nature. process is advantageous conventional physical chemical procedures. New studies have been conducted determine biomedical efficacy against various diseases. Unfortunately, there inadequate investigation into green-assisted nanocomposites. Incorporating phytosynthesized therapeutic interventions not only enhances healing processes but also augments host's immune defenses infections. highlights phytosynthesis applications, including antibacterial, antidiabetic, antiviral, antioxidant, antifungal, anti-cancer, other as well toxicity. explores mechanistic action achieve designated tasks. Biogenic for multimodal imaging potential exchange methods materials Well-designed utilized innovative theranostic agents subsequent objective efficiently diagnosing treating a variety human disorders.

Язык: Английский

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Multifunctional chitosan/carbon dots/sodium alginate/zinc oxide double-layer sponge hydrogel with high antibacterial, mechanical and hemostatic properties

OpenNano, Год журнала: 2023, Номер 12, С. 100162 - 100162

Опубликована: Май 10, 2023

Due to the fact that bacterial contamination of wounds is cause increased morbidity and mortality today, various antimicrobial wound dressings are developing prevent contamination. In addition, an ideal dressing should have proper mechanical hemostatic properties maintain healing conditions. Here, a double-layer sponge hydrogel nanocomposite was designed manufactured by combining zinc oxide nanoparticles (ZnONPs) with different concentrations in layer green carbon dots layer. The surface morphology two layers investigated using scanning electron microscope. X-ray diffraction proved presence ZnONPs. Physical tests showed decrease water absorption vapor transmission rate increase blood ZnO. suitable support dots. By both layers, were greatly enhanced. highest concentration ZnO excellent inhibition 41 mm against Pseudomonas aeruginosa bacteria 25 Staphylococcus aureus. Finally, vitro clotting animal confirmed power maximum

Язык: Английский

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Silk fibroin-based scaffolds for wound healing applications with metal oxide nanoparticles

Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 96, С. 105689 - 105689

Опубликована: Апрель 21, 2024

In the last few years, wound healing and development of "ideal" biomaterials that provide quick recovery minimize scarring have represented one most important priorities researchers. this direction, silk fibroin (SF) scaffolds gained substantial awareness, as a promising polymer owing to their increased biocompatibility, outstanding mechanical properties, biodegradability, especially tensile strength. Furthermore, SF is acknowledged accelerate process by encouraging cell growth proliferation, also migration different types cells are included in stages process. Therefore, metal oxide nanoparticles (NPs), such iron (FeO), copper (CuO), zinc (ZnO), or magnesium (MgO) NPs, been extensively researched for antimicrobial properties ability enhance tissue regeneration addition SF. When introduced within scaffolds, these NPs impart enhanced including improved scaffold stability durability. Moreover, presence could increase biocompatibility facilitating adhesion, migration, ultimately promoting processes. The incorporation other natural polymers into has thus emerged favorable method therapeutic potential developed biomaterial. This review aims an overview advancements containing applications.

Язык: Английский

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Investigating the absorbent properties of carboxymethyl cellulose-chitosan‑carbon dots nanocomposite sponge using photoacoustic microscopy

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142517 - 142517

Опубликована: Март 1, 2025

Язык: Английский

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Green Nanomaterials for Smart Textiles Dedicated to Environmental and Biomedical Applications

Materials, Год журнала: 2023, Номер 16(11), С. 4075 - 4075

Опубликована: Май 30, 2023

Smart textiles recently reaped significant attention owing to their potential applications in various fields, such as environmental and biomedical monitoring. Integrating green nanomaterials into smart can enhance functionality sustainability. This review will outline recent advancements incorporating for applications. The article highlights nanomaterials’ synthesis, characterization, textile development. We discuss the challenges limitations of using future perspectives developing environmentally friendly biocompatible textiles.

Язык: Английский

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Multifunctional polyvinyl alcohol/poly-dopamine hydrogels loaded with bio-nano composites promote wound healing by repairing endogenous electric fields

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 272, С. 132763 - 132763

Опубликована: Май 29, 2024

Язык: Английский

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Plant-Based nanostructure for wound healing – An emerging paradigm for effective therapy

Inorganic Chemistry Communications, Год журнала: 2024, Номер 162, С. 112162 - 112162

Опубликована: Фев. 6, 2024

Язык: Английский

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Effective antibacterial agents in modern wound dressings: a review

Biofouling, Год журнала: 2024, Номер 40(5-6), С. 305 - 332

Опубликована: Июнь 5, 2024

Wound infections are a significant concern in healthcare, leading to long healing times. Traditional approaches for managing wound rely heavily on systemic antibiotics, which associated with the emergence of antibiotic-resistant bacteria. Therefore, development alternative antibacterial materials care has gained considerable attention. In today's world, new generations dressing commonly used heal wounds. These dressings keep and area around it moist improve healing. However, this environment can also foster an that is favorable growth Excessive antibiotic use poses threat human health causes bacterial resistance, so new-generation must be designed developed reduce risk infection. using antimicrobial compounds minimize colonization, making them best way avoid open We aim provide readers comprehensive understanding latest advancements management.

Язык: Английский

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Synthesis of rice husk-zinc oxide-chitosan-based sponge: a green and eco-friendly nanocomposite for enhanced antibacterial, hemostasis, and wound healing applications

Journal of environmental chemical engineering, Год журнала: 2024, Номер 12(6), С. 114705 - 114705

Опубликована: Ноя. 6, 2024

Язык: Английский

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