Starch - Stärke, Год журнала: 2025, Номер unknown
Опубликована: Фев. 10, 2025
ABSTRACT The biocompatible and biodegradable polysaccharide starch is a great platform for the development of nanoparticles (NPs). Due to its special qualities, which include high stability, low toxicity, ease modification, it desirable option administration anticancer drugs. Targeted cancer therapy has found potential carrier in starch‐based (SNPs). SNPs can be functionalized with ligands target cells particular. These allow targeted medication delivery by identifying overexpressed receptors on tumor surfaces. have been studied relation chemotherapeutics, siRNAs, photothermal treatments, among other agents. They are also used combination therapy, where their combined targeting improves treatment outcomes. being evaluated number clinical trials. trials evaluate patient outcomes, safety, efficacy offer important information future uses. Regulatory bodies closely monitor various treatments based NPs. Clinical translation requires an understanding safety profiles, biodistribution, clearance mechanisms. In this review, we examine enhance through drug targeting.
Язык: Английский