Core-shell structured BN/SiO2 nanofiber membrane featuring with dual-effect thermal management and flame retardancy for extreme space thermal protection

Science Bulletin, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Nanozymes meet hydrogels: Fabrication, progressive applications, and perspectives

Advances in Colloid and Interface Science, Год журнала: 2025, Номер 338, С. 103404 - 103404

Опубликована: Янв. 23, 2025

Язык: Английский

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Ag quantum dots doped poly (vinyl alcohol)/chitosan hydrogel coatings to prevent catheter-associated urinary tract infections

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136405 - 136405

Опубликована: Окт. 16, 2024

Язык: Английский

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Preparation of Antibacterial and Antiadhesive Urinary Catheters with Robust Double-Network Gelatin-Polyacrylamide-Ag Nanoparticle Hydrogel Coatings

ACS Applied Polymer Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 13, 2025

Urinary catheter surfaces are susceptible to bacterial contamination, contributing catheter-associated urinary tract infections (CAUTIs). Although hydrogel coatings have exhibited potential in preventing bacteria adhesion and biofilm, they frequently experience poor bond strength with substrates weak mechanical properties, leading delamination or fracture during clinical use. In this paper, we developed a robust double network gelatin-polyacrylamide (PAAm)-Ag nanoparticle (GPA-0.01) coating on Foley-type double-lumen medical latex catheters (UCs). The study revealed that the GPA-0.01 slow swelling ratio, strong structural stability, excellent rheological ensuring durability of hydrogel-coated UCs even under harsh conditions. Furthermore, displayed exceptional hydrophilic lubricating along various substrates. More importantly, demonstrated significant antibacterial effects against Gram-negative Escherichia coli both outer lumen (inner) surfaces, as well antiadhesion properties could potentially reduce CAUTIs. Additionally, showed cytocompatibility blood compatibility vitro. proposed antibiofouling property was attributed synergistic effect PAAm gelatin long-lasting linked gradual release silver nanoparticles. Overall, demonstrates addressing resistance CAUTIs, promising applications for sustained biomedical devices.

Язык: Английский

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A feasible strategy of Ag nanoparticles-sodium alginate-polyacrylamide-polyvinyl alcohol hydrogel coatings for preventing catheter-associated urinary tract infections

Progress in Organic Coatings, Год журнала: 2024, Номер 196, С. 108706 - 108706

Опубликована: Авг. 5, 2024

Язык: Английский

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Mucus Mimic Hydrogel Coating for Lubricous, Antibiofouling, and Anti-Inflammatory Urinary Catheters

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(35), С. 46177 - 46190

Опубликована: Авг. 22, 2024

Silicone is a common elastomer used in indwelling urinary catheters, and catheters are widely various medical applications due to their exceptional biocompatibility, hypoallergenic properties, flexibility. However, silicones exhibit hydrophobic characteristics, lack inherent biolubrication, susceptible nonspecific biosubstance adsorption, resulting complications including but not limited tissue trauma, postoperative pain, tract infections (UTIs). The development of effective surface designs for biomedical mitigate invasive damage UITs has been longstanding challenge. Herein, we present novel approach prepare mucus mimic hydrogel coating. A thin layer containing xylitol fabricated via photopolymerization. modification technique the interface-initiated polymerization method ensure robust interfacial coherence. resultant coating exhibits low friction coefficient (CoF ≈ 0.1) catheter applications. Benefiting from hydration antifouling unit, hydrogel-coated surfaces (pAAAMXA) demonstrate outstanding antibiofouling properties against proteins (98.9% reduction relative pristine polydimethylsiloxane (PDMS)). Furthermore, pAAAMXA shows general adhesion resistance bacteria primarily responsible (Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Methicillin-resistant strains (MRSA), epidermidis epidermidis)) without compromising biotoxicity (cell viability 98%). In vivo, coated with displayed excellent bio substance, anti-inflammatory characteristics. This work describes promising alternative conventional silicone offering potential clinical interventional procedures minimized complications.

Язык: Английский

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Bioinspired Nanomaterials to Combat Microbial Biofilm and Pathogen Challenges: A Review

ACS Applied Nano Materials, Год журнала: 2024, Номер 7(22), С. 25287 - 25313

Опубликована: Ноя. 12, 2024

The emergence of antibiotic-resistant biofilms poses a significant challenge in healthcare, as these complex microbial communities demonstrate an increased resistance to conventional treatment methods. Traditional antibiotics often fail against biofilms, resulting persistent infections and failures. To address this urgent issue, innovative strategies such bioinspired nanomaterials, antimicrobial peptides, quorum sensing inhibitors, combination therapies show promise disrupting biofilm structures, enhancing activity, overcoming mechanisms. Bioinspired nanomaterials have emerged pivotal approach for tackling the challenges presented by pathogens across various sectors, including industry, environmental protection. Their advantages include enhanced biocompatibility, targeted delivery, improved efficacy formation threats. Recent advancements highlight potential solutions, nanoparticles, smart nanocarriers, surface modifications, nanozymes, combating biofilm-related issues. Despite progress nanomaterial research, remain. intricate interactions within evolving nature necessitate multidisciplinary approaches. Furthermore, translating laboratory findings into practical applications faces obstacles related scalability, stability, regulatory compliance. Future are expected focus on multifunctional nanoparticles that disrupt advanced modifications better interaction, nanocarriers nanozymes dismantle structures. This review focuses development application pathogen challenges. It emphasizes roles targeting capabilities. Additionally, explores formulating management practices, providing insights advantages, limitations, future perspectives

Язык: Английский

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Efficiently selective inactivation of Gram-positive bacteria by MCM-41 molecular sieve-supported copper-based self-cascading nanozymes

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160948 - 160948

Опубликована: Фев. 1, 2025

Язык: Английский

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Group IB Metal‐Based Nanomaterials for Antibacterial Applications

Small Science, Год журнала: 2025, Номер unknown

Опубликована: Март 9, 2025

Pathogenic bacteria pose significant threats to human health. In recent years, escalating bacterial resistance against antibiotics has diminished their efficacy in treating infections like pneumonia, tuberculosis, and sepsis, making some cases virtually untreatable. Hence, there is an urgent demand for novel approaches combat threats. Group IB metal‐based nanomaterials including copper, silver, gold have attracted considerable attention the field of antibacterial research owing remarkable broad‐spectrum bactericidal properties. Their high efficacy, ease synthesis, amenability functionalization render group highly promising diverse applications domain. This review comprehensively elucidates on mechanisms IB‐group addressing infections. Additionally, insights into challenges associated with utilizing such purposes while outlining future directions are provided.

Язык: Английский

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Research progress of hydrogels in the prevention of pelvic inflammatory disease

MedComm – Biomaterials and Applications, Год журнала: 2024, Номер 3(4)

Опубликована: Сен. 30, 2024

Abstract Pelvic inflammatory disease (PID) is a critical global health concern with the potential to lead adverse outcomes, including infertility and chronic pelvic pain. Since PID often caused by ascending vaginal infections or urinary tract infections, understanding treatment of both preventing PID. Meanwhile, emergence drug‐resistant persistently infected strains poses growing challenge. This review discusses current clinical treatments for prevention from physiologic basis PID, as well summarizes advantages research progress hydrogels in In contrast conventional treatments, serve excellent vehicles drug delivery, maintaining presence at target site controlling its release. context (UTIs), are employed primarily coatings on catheters prevent treat catheter‐associated UTIs. Finally, this limitations future directions development aim elucidating avenues informing further research.

Язык: Английский

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