Multifunctional Ultra‐Bright Plasmonic Gold@Fluorescence Nanoprobe for Biomedical Applications

Aggregate, Год журнала: 2025, Номер unknown

Опубликована: Фев. 6, 2025

ABSTRACT Metal‐enhanced fluorescence (MEF) represents a captivating phenomenon that transpires when fluorophores are situated in close vicinity to the surface of metallic nanostructures, leading nuanced augmentation their fluorescent characteristics. Given its efficacy enhancing excitation rates, quantum yield, and photostability, MEF has firmly established itself as highly valuable tool for augmenting biosensor sensitivity, bioimaging clarity, intensifying therapeutic responses. Notably, plasmonic gold inherently advantageous MEF, have been widely utilized signal amplification, labeling, theranostics. In this endeavor, we undertake comprehensive examination MEF‐enabled meticulously analyzing fundamental enhancement mechanisms, crucial influencing factors, diverse modes enhancement. Furthermore, spotlight exemplary applications these nanostructures biosensing, bioimaging, theranostics, underscoring revolutionary potential. Ultimately, offer glimpse into future prospects improvement challenges beset gold‐based MEF. Our attention is steadfastly directed toward essential scientific questions technical hurdles remain be surmounted, inviting readers partake an exciting exploration dynamic promising field.

Язык: Английский

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Electron Transfer-Driven Nanozymes Boost Biosensor Sensitivity via a Synergistic Signal Amplification Strategy

ACS Nano, Год журнала: 2025, Номер unknown

Опубликована: Март 3, 2025

The conventional gold nanoparticles (AuNPs) with insufficient brightness face substantial challenges in developing a sensitive lateral flow immunoassay (LFIA). Herein, multibranched manganese–gold (Mn–Au) (MnAuNPs) Au core–Mn shell nanostructure were synthesized by one-pot method. Mn of valence-rich and core high electron transfer efficiency endowed MnAuNPs oxidase-like activity, which oxidized 3,3′,5,5′-tetramethylbenzidine (TMB) only transfer. Ox-TMB, was the oxidation product TMB, is an excellent photothermal agent. Furthermore, synergistic effect ox-TMB significantly enhanced conversion efficiency. has enabled highly quantitative detection. LFIA based on (cascade LFIA) achieved detection Escherichia coli O157:H7. entire process completed 25 min. limit cascade 239 CFU mL–1, 37.21-fold lower than that AuNPs-LFIA (8892 mL–1). recoveries 82.63–111.67%, coefficients variation 4.28–14.19%. Overall, this work suggests potential development broadens biosensing strategies for point-of-care testing.

Язык: Английский

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Bidirectional “Win–Win”: Asymmetrical Nanobowl-Coupled Aggregation-Induced Emissive Nanosilicon-Enhanced Immunochromatographic Strips for the Ultrasensitive Detection of Salmonella typhimurium

Analytical Chemistry, Год журнала: 2024, Номер 96(45), С. 18204 - 18213

Опубликована: Ноя. 1, 2024

The lack of nanoprobes with an efficient signal response and overlook cooperation between can be responsible for the unsatisfactory analytical performance immunochromatographic strips (ITSs). Herein, asymmetrical nanobowl-confined innumerable gold nanoparticles (AuNPs) (AuNPs@AFRNBs) to enhance light absorption are developed quenching fluorescence aggregation-induced emissive (AIE) nanosilicons, which is used construction a bidirectional complementary-enhanced ITS (BC-ITS) ultrasensitively detect

Язык: Английский

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Triple-readout immunoassay based on copper ion trigger for the detection of Ochratoxin A

Analytica Chimica Acta, Год журнала: 2025, Номер unknown, С. 343750 - 343750

Опубликована: Янв. 1, 2025

Язык: Английский

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Ru nanoclusters engineer Prussian blue analog nanocubes for multiple active sites synergistic catalysis enabling high-performance bacterial detection

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160553 - 160553

Опубликована: Фев. 1, 2025

Язык: Английский

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The Anisotropic and Isotropic Gold Nanomaterials Continue to Heat Up: From Properties to Food Safety Monitoring

Trends in Food Science & Technology, Год журнала: 2025, Номер unknown, С. 104941 - 104941

Опубликована: Фев. 1, 2025

Язык: Английский

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Recent Advances in Nanomaterials for Enhanced Colorimetric Detection of Viruses and Bacteria

Chemosensors, Год журнала: 2025, Номер 13(3), С. 112 - 112

Опубликована: Март 19, 2025

The increasing prevalence of pathogen outbreaks underscores the urgent need for rapid, accurate, and cost-effective diagnostic tools. Colorimetric detection has gained significant attention among available techniques due to its simplicity, portability, potential point-of-care applications. nanomaterial-based colorimetric field continues evolve, with innovations focusing on improving sensitivity, specificity, robustness, cost-effectiveness, friendly analysis. Additionally, efforts address limitations, such as stability environmental impact, pave way more sustainable reliable solutions. This review highlights recent advances in nanomaterials last five years.

Язык: Английский

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Silver amplified immunosensor via effective fluorogenic Ag+-imidazole aggregation for detection of AFB1

Analytica Chimica Acta, Год журнала: 2024, Номер 1330, С. 343297 - 343297

Опубликована: Окт. 2, 2024

Язык: Английский

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